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Center Core
Microbiome Core

Center University of Massachusetts Medical School
Description The human gut microbiome consists of trillions of bacteria that have been shown
to affect multiple organ systems including the brain, immune system, endocrine
system, and metabolism, and may play an important role in the pathogenesis of
major human diseases including type 2 diabetes. Our new Microbiome Core is
directed by Dr. Beth McCormick (Professor and Vice Chair of Microbiology and
Physiological Systems), who is a leading scientist in microbiome research, and
provides expert knowledge and state-of-the-art tools for researchers to study
gut microbiota in mouse models of human diseases to advance our understanding of
this critical interplay.

The Microbiome Core offers:
• Consultation service for the design and implementation of gut microbiome
studies
• Sample preparation and quality control tests
• Metagenomic 16S rRNA NextGen sequencing methodologies
• Post-sequencing consultation for data analysis, interpretation, upload, and
presentation
• Fecal Microbiota Transplant (FMT) procedure to selectively alter gut
microbiota in mice
• Chronic and acute antibiotic treatment to induce altered gut microbiota in
mice


 Members
NameInstitutionEmailTitle
Beth McCormickUniversity of Massachusetts Medical Schoolbeth.mccormick@umassmed.eduDirector

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