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Experiment

Comprehensive Metabolic Clamp and Cage Study to Assess Energy Balance and
Insulin Sesitivity in Muscle-Specific BDNF KO Mice Fed High-Fat Diet for 12
weeks
Summary Data Summary
Investigator Chan, Chi
Description MCK-Cre expressing BDNF (brain-derived neurotrophin) KO mice

Applicable research area(s): Diabetes, Obesity, Metabolism
Status Completed
Public Release 10/21/2020
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals17
Experimental Conditions3
Catalog Items5
Curation Info (# flags)1
Phenotype Assays19
Phenotype Measurements475
Histology Images0
Publications0
Phenotypes6


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
7
0
0
C57BL/6-Bdnfflox/flox Tg(Ckm-Cre)
7
0
0
Bdnf fl/fl
3
0
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 LabDiet 5P75/5P76
Prolab 5P75 and 5P76 Isopro 3000 are the irradiated forms of RMH 3000 (5P00). The product has been irradiated to virtually bacteria-free dietary control. Protien 22.5%, Fat 5.4% Cholesterol 195 ppm
 Research Diets - D12492i
Irradiated form of D12492, Rodent Diet with 60% kcal% fat.

Experimental Factor: Time Since Baseline (day)

 Time Since Baseline
Number of days since the baseline measurement was taken.



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