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Experiment

Metabolic Clamp Study in HFD-fed p5.4-TNMD-Flag Mice (Batch 2)
Summary Data Summary
Investigator Czech, Michael
Description 5 HFD-fed p5.4-TNMD-Flag mice for body composition, metabolic cage analysis, and
a 2-hr hyperinsulinemic-euglycemic clamp study after a 4-hr fasting (NO
overnight fasting).

~Metabolic cages for a week (Activity, food intake, RER)
~Surgery for hyperinsulinemic-euglycemic clamp
~Measurement of weight before and after surgery, wait until regain pre surgery
weight.
~Glucose uptake in Sq FAT, Visceral FAT, Brown FAT, Muscle, Liver and liver
glucose output.

Applicable research area(s): Diabetes, Metabolism, Obesity
Status Completed
Public Release 12/10/2017
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals8
Experimental Conditions1
Catalog Items6
Curation Info (# flags)2
Phenotype Assays20
Phenotype Measurements158
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J +/+
0
5
0
p5.4-TNMD-Flag Mice
0
3
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor (Units)
Experimental Group


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