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Experiment

Analytical Study in Female FVB/N Mice Treated with hsiRNA-Targeted Knockdown of
Peptidyl-prolyl cis-trans isomerase B
Summary Data Summary
Investigator Khvorova, Anastasia
Description Treatment of cholesterol conjugated fully-modified hsiRNA
Hydrophobically modified, double stranded, small interfering RNA targeting PPIB
Cholesterol conjugate on the 5' end of the sense strand
Peptidyl-prolyl cis-trans isomerase B (PP1B)
Status Completed
Public Release 6/20/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals26
Experimental Conditions3
Catalog Items2
Curation Info (# flags)2
Phenotype Assays2
Phenotype Measurements36
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
FVB/N
26
0
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Cholesterol conjugated hsiRNA
Cholesterol was conjugated to hsiRNA (heterochromatic short interfering RNA).
 PBS
Phosphate-buffered saline is a buffer salt solution containing disodium hydrogen phosphate and sodium chloride.

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Time Since Drug Administered (hr)

 Time Since Drug Admi
The time, in hours, since the drug was administered to the subject.


Phenotype Assays Add / Edit



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