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Experiment

Metabolic Clamp Study in Sclerostin KO Mice
Summary Data Summary
Investigator Riddle, Ryan
Description Models Sclerosteosis, Van Buchem disease

In addition to high bone mass, KO mice exhibit a reduction in fat mass with
improved glucose tolerance and insulin sensitivity

Applicable research area(s): Metabolism, Diabetes
Status Completed
Public Release 3/23/2019
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainAnimal CountExperiment Description
Data Analysis
TypeCount
Animals14
Experimental Conditions1
Catalog Items4
Curation Info (# flags)3
Phenotype Assays14
Phenotype Measurements196
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J +/+
0
7
0
C57BL/6-Sosttm1(KOMP)Vlcg
0
7
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.



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