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Experiment

Metabolic Cage Study to Assess Energy Balance in BAT-Rictor KO mice Fed Chow and
High-Fat Diet
Summary Data Summary
Investigator Guertin, David
Description The interplay between signal transduction pathways and metabolism in the control
of BAT thermogenesis is not well understood. Moreover, BAT-specific genetic
models of the mammalian target of rapamycin (mTOR) signaling pathways have not
been investigated. Thus studying the in vivo tissue specific role of mTOR
complex pathway with using their appropriate genetic models, is valuable in mTOR
biology field.

Applicable research area(s): Diabetes, Obesity, Metabolism, Cardiovascular
Status Completed
Public Release 11/2/2019
Animal Age Measured In: week(s) post-natal (w)
Data Analysis
TypeCount
Animals23
Experimental Conditions2
Catalog Items2
Curation Info (# flags)0
Phenotype Assays9
Phenotype Measurements207
Histology Images0
Publications0


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6J +/+
0
12
0
BAT-specific Rictor KO
0
11
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 LabDiet 5P75/5P76
Prolab 5P75 and 5P76 Isopro 3000 are the irradiated forms of RMH 3000 (5P00). The product has been irradiated to virtually bacteria-free dietary control. Protien 22.5%, Fat 5.4% Cholesterol 195 ppm
 Research Diets - D12492i
Irradiated form of D12492, Rodent Diet with 60% kcal% fat.



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