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Experiment

Metabolic Clamp Study to Assess Insulin Sensitivity in Diet-Induced Obese
C57BL/6J Mice Following Chronic GABA Treatment
Summary Data Summary
Investigator Jae Bum, KIM
Description Improvement or aggravation of glucose metabolism

Applicable research area(s): Diabetes, Metabolism, Obesity
Status Completed
Public Release 9/5/2020
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainAnimal Count
Data Analysis
TypeCount
Animals17
Experimental Conditions3
Catalog Items8
Curation Info (# flags)2
Phenotype Assays14
Phenotype Measurements238
Histology Images0
Publications0
Phenotypes3


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
17
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Drug Administered

 GABA
GABA (Gamma-Aminobutyric Acid) is the chief inhibitory neurotransmitter in the mammalian central nervous system. Its principal role is reducing neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for...
 Vehicle
Vehicle - Control

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Research Diets - D12492i
Irradiated form of D12492, Rodent Diet with 60% kcal% fat.



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