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Experiment

Metabolic Study-Metabolic Cage-Clamp in DMP1-Gsa KO Mice
Summary Data Summary
Investigator Fulzele, Keertik
Description These mice harbors osteocyte specific deletion of Gs-alpha generated by mating
DMP1-Cre mice with Gs-alpha floxed mice. The resulting DMP1-GsaKO mice are
severely osteopenic and have a dramatic decrease in body fat accumulation. The
decreased white fat depots were due to increased beige adipogenesis in these
mice.

Applicable research area(s): Diabetes, Obesity, Metabolism
Status Completed
Public Release 7/30/2017
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals10
Experimental Conditions1
Catalog Items4
Curation Info (# flags)2
Phenotype Assays17
Phenotype Measurements170
Histology Images0
Publications0
Phenotypes2


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
6
0
Dmp1-Gsa KO
0
4
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.



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