University of California Davis
University of Cincinnati Medical Center
University of Massachusetts Medical School
University of Michigan Medical School
Vanderbilt University School of Medicine
Protocols & Methods
Reagents & Resources
Tissues & Samples
Conditions of Use
Data Usage Policy
Energy Expenditure Analysis
CalR: Indirect Calorimetry Analysis
Guidelines & Policies
MMPC will provide the community with up-to-date information on new course availability. This page will be updated periodically with current course information.
Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis
Glucose Clamping The Conscious Mouse: A Laboratory Course
An Organ Systems Approach to Experimental Targeting of the Metabolic Syndrome
Back to Top
Tracers in Metabolic Research
12th Annual Course on Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis
October 21 - 25, 2019
Homewood Suites by Hilton® Nashville Vanderbilt in Nashville, TN
Owen P. McGuinness, PhD, Elizabeth J. Parks, PhD
Sponsored by Mouse Metabolic Phenotyping Centers (MMPC)
This is the 12th annual offering of a course that provides basic introductory and comprehensive information on performing metabolic studies using tracers labeled with radioactive or stable isotopes, in man and in animals. The course is designed for beginners as well as those with experience who wish to expand their capabilities to more sophisticated problems. The faculty is well-versed in a variety of applications and methodologies.
Techniques will be presented for investigating whole body metabolism, for metabolite balance across organs, intracellular flux rates and pathway regulation. General aspects of modeling will be considered, as well as specific applications in the study of carbohydrate, fat, protein metabolism and energy balance. Theoretical and practical matters related to sample analysis by mass spectrometry and NMR will be discussed, including detailed numerical examples of calculations involved in determining isotopic enrichment and basic kinetic parameters. Advanced lectures will discuss in more detail the use of positional and mass isotopomer analysis for intracellular flux rates and various aspects of protein and amino acid metabolism. Applications in humans and animal models (particularly mouse) will be considered.
Course material will be presented in organized lectures and informal workshops. Problem sets and discussion questions will highlight each lecture. Lecture notes and problem sets will be available to registrants to be downloaded from the course website. In addition to organized sessions, attendees are encouraged to present their own projects and will have ample opportunities for personal interaction with faculty members to discuss issues of particular interest to them in depth.
Scholarships for graduate students and postdoctoral fellows to cover registration fees are available.
More information including the course syllabus, registration, and hotel information can be found at
If you have questions, please contact Eann Malabanan (
) or 615-343-1065).
You may also contact Maren Laughlin, Ph.D. at
or Owen McGuinness Ph.D. at
Registration Link (opens June 1st):
*Registration deadline: Oct. 1st
*Note: Register at your earliest convenience. This course typically reaches capacity (90 attendees) prior to registration deadline.
Download the 2019 Course Brochure
Download the 2019 Course Syllabus
Back to Top
Glucose Clamping The Conscious Mouse
The Vanderbilt-NIDDK Mouse Metabolic Phenotyping Center (MMPC) presents the 16
semiannual course –
Glucose Clamping The Conscious Mouse:
A Laboratory Course
March 4 – 8, 2019
September 16 – 20, 2019
Vanderbilt-NIDDK Mouse Metabolic Phenotyping Center
: Vanderbilt University
8455 Medical Research Building IV
A week-long course to familiarize participants with methods, protocols and quantitative tools necessary to perform glucose clamps in the conscious mouse.
: David Wasserman, PhD, Owen McGuinness, PhD, Julio Ayala, PhD, Louise Lantier, PhD
for more details.
Back to Top
There was a problem with the page:
Safari Browser Detected...
We strive to make the MMPC site compatable with as many browsers as possible, but some of our third party tools don't work with the Safari browser.
In order to explore this site we highly recommend using the most recent versions of the following browsers:
Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the MMPC using the following text:
Financial support for this work was provided by the NIDDK Mouse Metabolic Phenotyping Centers (National MMPC, RRID:SCR_008997,
) under the MICROMouse Program, grants DK076169.
Citation text and image have been copied to your clipboard. You may now paste them into your document. Thank you!
Warranty disclaimer and copyright notice
THE NATIONAL MMPC MAKES NO REPRESENTATION ABOUT THE SUITABILITY OR ACCURACY OF THE SOFTWARE OR DATA FOR ANY PURPOSE, AND MAKES NO WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR THAT THE USE OF THE SOFTWARE OR DATA WILL NOT INFRINGE ANY THIRD PARTY PATENTS, COPYRIGHTS, TRADEMARKS, OR OTHER RIGHTS. THE SOFTWARE AND DATA ARE PROVIDED "AS IS".
The Mouse Metabolic Phenotyping Centers (MMPC) is an NIDDK funded consortium and adheres to the
NIH Data Sharing Policy
MMPC clients make their data freely available whereby MMPC users may freely build upon, enhance and reuse those data for any purpose without restriction. Scholarly citation norms must be followed for content reuse. Please acknowledge the MMPC using the following text: 'The MMPC data used in this manuscript was supported by the NIDDK National Mouse Metabolic Phenotyping Centers (National MMPC, RRID:SCR_008997,
)'. To cite specific MMPC centers, please use the appropriate RRID available from the MMPC website (
Please note that the acknowledgment text includes a Research Resource Identifier (RRID) for the MMPC CU and Centers. Reproducibility is one of the corner stones of effective, open and transparent biomedical published research. However, too often, resources (e.g. model organisms, antibodies, and tools) are not reported with adequate detail to ensure others can replicate or expand upon the published results. The Research Resource Identification Initiative (#RII) seeks to change these limitations in reporting by the use of unique Research Resource Identifiers (RRIDs). This initiative is designed to encourage authors to provide identification of the types of resources used in their research by adding a globally unique accession number to the resources described in the their manuscripts. These identifiers, called RRIDs, will allow authors to cite the resources that they use in their manuscripts. RRIDs allow for easy tracking of all papers that have used the same resource making it easy to access how the same resources works in other scenarios.
It is expected that MMPC users follow scholarly citation norms, giving credit to fellow scholars when accessing/using protocols and data, including data derived by MMPC (such as summary data) and any plots, tables or screenshots depicting those data.
It is possible for invalid or incomplete results to be presented on the MMPC web site due to software bugs, data problems, or artifacts of human error. Data sets are not necessarily static; we reserve the right to post corrections and updates as needed.
Data contributors and data users may not use MMPC in any unlawful manner, or in any manner that could impair MMPC services, security or functionality. Automated usage (webcrawlers and similar) must observe each page's "meta robots" html tags and space requests by ≥ 2 seconds. We reserve the right to block any IP associated with what we consider to be excessive or abusive usage patterns, and/or to take any action we deem necessary.
The MMPC is a National Institutes of Health-sponsored resource that provides experimental testing services to scientists studying diabetes, obesity, diabetic complications, and other metabolic diseases in mice.
Interested in receiving MMPC News?
2017 National MMPC. All Rights Reserved.