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Minimum testing required of mice received from other institutions
Each institution will have unique requirements for shipping of mice to their facility. Additional testing may be required prior to shipping. Health reports (with the most recent being no older than 3 months) must be provided to the receiving institution's Shipping Coordinator and reviewed before the shipment will be approved. The testing required will include, but is not limited to:
  • Ectromelia (ECTRO)
  • Lymphocytic choriomenengitis virus (LCMV)
  • Mouse adenoviruses (MAD)
  • Mouse hepatitis virus (MHV)
  • Mouse parvoviruses (MPV)
  • Mouse rotavirus (EDIM)
  • Mycoplasma pulmonis (MPUL)
  • Pneumonia virus of mice (PVM)
  • Reovirus (REO)
  • Sendai virus (SEND)
  • Theiler's virus (GD-7)
  • Fur mites
  • Pinworms
Shipping Please contact the Shipping Coordinator at the receiving institution for details related to shipping of mice and approved transport carriers.

Quarantine Testing
MMPC Center Quarantine Length Testing Strategy Treatments During Quarantine
University of California-Davis No quarantine (rigorous review of health status & exclusion list) N/A N/A
University of Cincinnati 4 week quarantine PCR of colony animals Topical Selamectin
University of Massachusetts Medical School
Option 1: Conventional quarantine (5-6 weeks)

Option 2: Expedited quarantine (2.5-3 weeks)
Option 1: Serology of dirty bedding sentinels; parasite PCR

Option 2: PCR of colony animals
Fenbendazole food and Ivermectin water
University of Michigan 3-4 week quarantine PCR of colony animals None
Vanderbilt University 6-8 week quarantine MHV PCR of colony mice, Serology and parasitology of dirty bedding sentinels Ivermectin food or topical spray
MMPC Center Caging Bedding Enrichment Water Diet
University of California-Davis Animal Care Systems Optimice caging Corn cob
* Bariatric mice housed on ALPHA- dri (no cob)
Enviro-dri and Nestlet
* Bariatric mice housed - Nestlet and Shepherd Shack (no Enviro-dri)
Water Bottles (Acidified, filtered & autoclaved) Envigo 2918
* Bariatric mice fed TD.06414 (60%HFD)
University of Cincinnati Alternate Design Static Microisolator Cage Corn cob (autoclaved) Nestlet or Crinkle Paper Water Bottles (R/O and UV Sterilized) Harlan Teklad 7912 Irradiated
University of Massachusetts Medical School Allentown Microvent ventilated microisolator Corn cob Nestlet and Envirodri Automatic watering (R/O and acidified) Prolab IsoPro RMH 3000 5P76 irradiated diet
University of Michigan Allentown ventilated microisolator Pure-o'Cel Envirodri or Nestlet Automatic water (filtered) or bottles (autoclaved) Lab Diet 5L0D (standard) or 5008 (breeders)
Vanderbilt University Allentown XJ ventilated microisolator Enrich-n'Pure
Paper nesting rolls in bedding
Optional Shepherd Shack
Water Bottles (filtered, acidified & autoclaved) Lab Diet 5L0D irradiated chow

Release of Protocol Information
All animal care protocols developed during the planning of this project will be shared with NIH.

  • Required Approvals:
    • All phenotyping tests carried out by an MMPC are approved by their respective Institutional Animal Care and Use Committees. However, additional information may be required from client investigators.

Committee on Animal Husbandry Issues

  • Kristin Grimsrud, DVM, PhD, University of California – Davis
  • Mahesh Jonnalagadda, DVM, DACLAM, University of Cincinnati
  • Samer Jaber, DVM, DACLAM, University of Massachusetts Medical School
  • Bob Dysko, DVM, DACLAM, University of Michigan
  • Erin Yu, DVM, DACLAM Vanderbilt University (Chair)


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