The MMPC web portal will provide a number of publications as a service to the community.
This page will be updated as publications become available to members and / or the public.
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Total Publications: 2285 (Showing 2285)
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| Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease.Srivastava SP, Zhou H, Shenoi R, Morris M, Lainez-Mas B, Goedeke L, Rajendran BK, Setia O, Aryal B, Kanasaki K, Koya D, Inoki K, Dardik A, Bell T, Fernández-Hernando C, Shulman GI, Goodwin JE Science advances, 2024 (10), eadn6068 | | Submitted Externally | 39630889 | Published | |
| SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts.Goedeke L, Ma Y, Gaspar RC, Nasiri A, Lee J, Zhang D, Galsgaard KD, Hu X, Zhang J, Guerrera N, Li X, LaMoia T, Hubbard BT, Haedersdal S, Wu X, Stack J, Dufour S, Butrico GM, Kahn M, Perry RJ, Cline GW, Young LH, Shulman GI The Journal of clinical investigation, 2024 (134) | | Submitted Externally | 39680452 | Published | |
| | | Submitted Externally | 39352758 | Published | |
| | | Submitted Externally | 38696337 | Published | |
| | | Submitted Externally | 39150395 | Published | |
| Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease.Gaspar RC, Sakuma I, Nasiri A, Hubbard BT, LaMoia TE, Leitner BP, Tep S, Xi Y, Green EM, Ullman JC, Petersen KF, Shulman GI American journal of physiology. Endocrinology and metabolism, 2024 (327), E524 - E532 | | Submitted Externally | 39171753 | Published | |
| Small molecules targeting selective PCK1 and PGC-1a lysine acetylation cause anti-diabetic action through increased lactate oxidation.Mutlu B, Sharabi K, Sohn JH, Yuan B, Latorre-Muro P, Qin X, Yook JS, Lin H, Yu D, Camporez JPG, Kajimura S, Shulman GI, Hui S, Kamenecka TM, Griffin PR, Puigserver P Cell chemical biology, 2024 (31), 1772 - 1786.e5 | | Submitted Externally | 39341205 | Published | |
| | | Submitted Externally | 39435657 | Published | |
| | | Submitted Externally | 39445824 | Published | |
| | | Submitted Externally | 39456952 | Published | |
| | | Submitted Externally | 38695083 | Published | |
| Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy.Eid SA, Elzinga SE, Guo K, Hinder LM, Hayes JM, Pacut CM, Koubek EJ, Hur J, Feldman EL Translational research : the journal of laboratory and clinical medicine, 2024 (270), 24 - 41 | | Submitted Externally | 38556110 | Published | |
| | | Submitted Externally | 38743615 | Published | |
| The mouse metabolic phenotyping center (MMPC) live consortium: an NIH resource for in vivo characterization of mouse models of diabetes and obesity.Laughlin M, McIndoe R, Adams SH, Araiza R, Ayala JE, Kennedy L, Lanoue L, Lantier L, Macy J, Malabanan E, McGuinness OP, Perry R, Port D, Qi N, Elias CF, Shulman GI, Wasserman DH, Lloyd KCK Mammalian genome : official journal of the International Mammalian Genome Society, 2024 | | Submitted Externally | 39191872 | Published | |
| | | Submitted Externally | 38932722 | Published | |
| Thrombospondin-1 promotes fibro-adipogenic stromal expansion and contractile dysfunction of the diaphragm in obesity.Buras ED, Woo MS, Kaul Verma R, Kondisetti SH, Davis CS, Claflin DR, Converso-Baran K, Michele DE, Brooks SV, Chun TH JCI insight, 2024 (9) | | Submitted Externally | 38954467 | Published | |
| | | Submitted Externally | 39007235 | Published | |
| | | Submitted Externally | 38502790 | Published | |
| Control of Physiologic Glucose Homeostasis via the Hypothalamic Modulation of Gluconeogenic Substrate Availability.Hashsham A, Kodur N, Su J, Tomlinson AJ, Yacawych WT, Flak JN, Lewis KT, Oles LR, Mori H, Bozadjieva-Kramer N, Turcu AF, MacDougald OA, Myers MG, Affinati AH bioRxiv : the preprint server for biology, 2024 | | Submitted Externally | 38826340 | Published | |
| | | Submitted Externally | 38353639 | Published | |
| The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-dependent manner.Blevins JE, Honeycutt MK, Slattery JD, Goldberg M, Rambousek JR, Tsui E, Dodson AD, Shelton KA, Salemeh TS, Elfers CT, Chichura KS, Ashlaw EF, Zraika S, Doyle RP, Roth CL Frontiers in endocrinology, 2024 (15), 1432928 | | Submitted Externally | 39104812 | Published | |
| MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis.Park J, Hall C, Hubbard B, LaMoia T, Gaspar R, Nasiri A, Li F, Zhang H, Kim J, Haeusler RA, Accili D, Shulman GI, Yu H, Choi E Diabetes, 2023 (72), 1781 - 1794 | | Submitted Externally | 37725942 | Published | |
| | | Submitted Externally | 37930356 | Published | |
| | | Submitted Externally | 37961647 | Published | |
| | | Submitted Externally | 38048597 | Published | |
| Spatial-Temporal Oxygenation Mapping Using a Near-Infrared Optical Scanner: Towards Peripheral Vascular Imaging.Leiva K, Leizaola D, Gonzalez I, Dargam V, Alirezaei H, Kaile K, Robledo E, Hutcheson J, Godavarty A Annals of biomedical engineering, 2023 (51), 2035 - 2047 | | Submitted Externally | 37204547 | Published | |
| | | Submitted Externally | 37755291 | Published | |
| | | Submitted Externally | 37790549 | Published | |
| | | Submitted Externally | 36933143 | Published | |
| | | Submitted Externally | 37230380 | Published | |
| | | Submitted Externally | 37366543 | Published | |
| | | Submitted Externally | 37383542 | Published | |
| Dietary interventions improve diabetic kidney disease, but not peripheral neuropathy, in a db/db mouse model of type 2 diabetes.Eid SA, O'Brien PD, Kretzler KH, Jang DG, Mendelson FE, Hayes JM, Carter A, Zhang H, Pennathur S, Brosius FC, Koubek EJ, Feldman EL FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023 (37), e23115 | | Submitted Externally | 37490006 | Published | |
| Species-specific roles for the MAFA and MAFB transcription factors in regulating islet ß cell identity.Cha J, Tong X, Walker EM, Dahan T, Cochrane VA, Ashe S, Russell R, Osipovich AB, Mawla AM, Guo M, Liu JH, Loyd ZA, Huising MO, Magnuson MA, Hebrok M, Dor Y, Stein R JCI insight, 2023 (8) | | Submitted Externally | 37606041 | Published | |
| Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines.Zhang Y, Barupal DK, Fan S, Gao B, Zhu C, Flenniken AM, McKerlie C, Nutter LMJ, Lloyd KCK, Fiehn O Metabolites, 2023 (13) | | Submitted Externally | 37623890 | Published | |
| | | Submitted Externally | 37662392 | Published | |
| | | Submitted Externally | 37677024 | Published | |
| The effect of surgical weight loss on diabetes complications in individuals with class II/III obesity.Reynolds EL, Watanabe M, Banerjee M, Chant E, Villegas-Umana E, Elafros MA, Gardner TW, Pop-Busui R, Pennathur S, Feldman EL, Callaghan BC Diabetologia, 2023 (66), 1192 - 1207 | | Submitted Externally | 36917280 | Published | |
| SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions.Pilat JM, Brown RE, Chen Z, Berle NJ, Othon AP, Washington MK, Anant SA, Kurokawa S, Ng VH, Thompson JJ, Jacobse J, Goettel JA, Lee E, Choksi YA, Lau KS, Short SP, Williams CS The Journal of clinical investigation, 2023 (133) | | Submitted Externally | 37166989 | Published | |
| Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis.Vázquez-Borrego MC, Del Río-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, Wnek M, Cordoba-Chacon J, Waxman DJ, Puchowicz MA, McGuinness OP, Kineman RD Metabolism: clinical and experimental, 2023 (144), 155589 | | Submitted Externally | 37182789 | Published | |
| Association between brain health outcomes and metabolic risk factors in persons with diabetes.Reynolds EL, Votruba K, Jack CR, Beare R, Reid RI, Preboske GM, Waseta C, Pop-Busui R, Nelson RG, Callaghan BC, Feldman EL Annals of clinical and translational neurology, References, 2023 | | Submitted Externally | 37518982 | Published | |
| | | Submitted Externally | 37546831 | Published | |
| Fibroblast growth factor-21 is required for weight loss induced by the glucagon-like peptide-1 receptor agonist liraglutide in male mice fed high carbohydrate diets.Le TDV, Fathi P, Watters AB, Ellis BJ, Besing GK, Bozadjieva-Kramer N, Perez MB, Sullivan AI, Rose JP, Baggio LL, Koehler J, Brown JL, Bales MB, Nwaba KG, Campbell JE, Drucker DJ, Potthoff MJ, Seeley RJ, Ayala JE Molecular metabolism, 2023 (72), 101718 | | Submitted Externally | 37030441 | Published | |
| Hepatic Phospholipid Remodeling Modulates Insulin Sensitivity and Systemic Metabolism.Tian Y, Mehta K, Jellinek MJ, Sun H, Lu W, Shi R, Ingram K, Friedline RH, Kim JK, Kemper JK, Ford DA, Zhang K, Wang B Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023 (10), e2300416 | | Submitted Externally | 37088778 | Published | |
| | | Submitted Externally | 37196974 | Published | |
| | | Submitted Externally | 37301941 | Published | |
| | | Submitted Externally | 37333314 | Published | |
| Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.Guilherme A, Rowland LA, Wetoska N, Tsagkaraki E, Santos KB, Bedard AH, Henriques F, Kelly M, Munroe S, Pedersen DJ, Ilkayeva OR, Koves TR, Tauer L, Pan M, Han X, Kim JK, Newgard CB, Muoio DM, Czech MP Cell reports, 2023 (42), 112488 | | Submitted Externally | 37163372 | Published | |
| Hypermetabolism in mice carrying a near-complete human chromosome 21.Sarver DC, Xu C, Rodriguez S, Aja S, Jaffe AE, Gao FJ, Delannoy M, Periasamy M, Kazuki Y, Oshimura M, Reeves RH, Wong GW eLife, 2023 (12) | | Submitted Externally | 37249575 | Published | |
| Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.Apiz Saab JJ, Dzierozynski LN, Jonker PB, AminiTabrizi R, Shah H, Menjivar RE, Scott AJ, Nwosu ZC, Zhu Z, Chen RN, Oh M, Sheehan C, Wahl DR, Pasca di Magliano M, Lyssiotis CA, Macleod KF, Weber CR, Muir A eLife, 2023 (12) | | Submitted Externally | 37254839 | Published | |
| | | Submitted Externally | 37367868 | Published | |
| Sexual Dimorphism in Lipid Metabolism and Gut Microbiota in Mice Fed a High-Fat Diet.Zhu Q, Qi N, Shen L, Lo CC, Xu M, Duan Q, Ollberding NJ, Wu Z, Hui DY, Tso P, Liu M Nutrients, 2023 (15) | | Submitted Externally | 37432375 | Published | |
| Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.Vohnoutka RB, Kuppa A, Hegde Y, Chen Y, Pant A, Tohme ME, Choi EK, McCarty SM, Bagchi DP, Du X, Chen Y, Chen VL, Mori H, Bielak LF, Maguire LH, Handelman SK, Sexton JZ, Saunders TL, Halligan BD, Speliotes EK Journal of molecular endocrinology, 2023 (70) | | Submitted Externally | 36748836 | Published | |
| | | Submitted Externally | 37131808 | Published | |
| Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT.Choi KM, Ko CY, An SM, Cho SH, Rowland DJ, Kim JH, Fasoli A, Chaudhari AJ, Bers DM, Yoon JC Molecular metabolism, 2023 (69), 101679 | | Submitted Externally | 36708951 | Published | |
| Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics.Guo K, Figueroa-Romero C, Noureldein M, Hinder LM, Sakowski SA, Rumora AE, Petit H, Savelieff MG, Hur J, Feldman EL Microbiome, 2023 (11), 52 | | Submitted Externally | 36922895 | Published | |
| Insulin-regulated serine and lipid metabolism drive peripheral neuropathy.Handzlik MK, Gengatharan JM, Frizzi KE, McGregor GH, Martino C, Rahman G, Gonzalez A, Moreno AM, Green CR, Guernsey LS, Lin T, Tseng P, Ideguchi Y, Fallon RJ, Chaix A, Panda S, Mali P, Wallace M, Knight R, Gantner ML, Calcutt NA, Metallo CM Nature, 2023 (614), 118 - 124 | | | 36697822 | Published | |
| | | Submitted Externally | 36752210 | Published | |
| | | Submitted Externally | 36904213 | Published | |
| Ultraviolet light oxidation of fresh hemoglobin eliminates aggregate formation seen in commercially sourced hemoglobin.Afzal A, Beavers WN, Skaar EP, Calhoun MC, Richardson KA, Landstreet SR, Cliffel DE, Wright D, Bastarache JA, Ware LB Blood cells, molecules & diseases, 2023 (98), 102699 | | Submitted Externally | 36027791 | Published | |
| | | Submitted Externally | 36088207 | Published | |
| | | Submitted Externally | 36472154 | Published | |
| | | Submitted Externally | 36480511 | Published | |
| Q-Flux: A method to assess hepatic mitochondrial succinate dehydrogenase, methylmalonyl-CoA mutase, and glutaminase fluxes in vivo.Hubbard BT, LaMoia TE, Goedeke L, Gaspar RC, Galsgaard KD, Kahn M, Mason GF, Shulman GI Cell Metabolism, 2023 (35), 212 - 226.e4 | | Submitted Externally | 36516861 | Published | |
| | | Submitted Externally | 36683455 | Published | |
| Anti-Inflammatory and Therapeutic Effects of a Novel Small-Molecule Inhibitor of Inflammation in a Male C57BL/6J Mouse Model of Obesity-Induced NAFLD/MAFLD.McCall KD, Walter D, Patton A, Thuma JR, Courreges MC, Palczewski G, Goetz DJ, Bergmeier S, Schwartz FL Journal of inflammation research, 2023 (16), 5339 - 5366 | | Submitted Externally | 38026235 | Published | |
| | | Submitted Externally | 36057462 | Published | |
| Towards differentiation of brain tumor from radiation necrosis using multi-parametric MRI: Preliminary results at 4.7 T using rodent models.Devan SP, Jiang X, Kang H, Luo G, Xie J, Zu Z, Stokes AM, Gore JC, McKnight CD, Kirschner AN, Xu J Magnetic resonance imaging, 2022 (94), 144 - 150 | | Submitted Externally | 36209946 | Published | |
| Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis.Schwager SC, Young KM, Hapach LA, Carlson CM, Mosier JA, McArdle TJ, Wang W, Schunk C, Jayathilake AL, Bates ME, Bordeleau F, Antonyak MA, Cerione RA, Reinhart-King CA eLife, 2022 (11) | | Submitted Externally | 36475545 | Published | |
| Activation of basal forebrain-to-lateral habenula circuitry drives reflexive aversion and suppresses feeding behavior.Swanson JL, Ortiz-Guzman J, Srivastava S, Chin PS, Dooling SW, Hanson Moss E, Kochukov MY, Hunt PJ, Patel JM, Pekarek BT, Tong Q, Arenkiel BR Scientific reports, 2022 (12), 22044 | | Submitted Externally | 36543829 | Published | |
| Early-life low-calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory function in rats.Tsan L, Chometton S, Hayes AM, Klug ME, Zuo Y, Sun S, Bridi L, Lan R, Fodor AA, Noble EE, Yang X, Kanoski SE, Schier LA JCI insight, 2022 (7) | | Submitted Externally | 36546482 | Published | |
| Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice.Henn RE, Elzinga SE, Glass E, Parent R, Guo K, Allouch AA, Mendelson FE, Hayes J, Webber-Davis I, Murphy GG, Hur J, Feldman EL Immunity & ageing : I & A, 2022 (19), 67 | | Submitted Externally | 36550567 | Published | |
| | | Submitted Externally | 35802127 | Published | |
| | | Submitted Externally | 36240668 | Published | |
| The gut peptide Reg3g links the small intestine microbiome to the regulation of energy balance, glucose levels, and gut function.Shin JH, Bozadjieva-Kramer N, Shao Y, Lyons-Abbott S, Rupp AC, Sandoval DA, Seeley RJ Cell Metabolism, 2022 (34), 1765 - 1778.e6 | | Submitted Externally | 36240758 | Published | |
| Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis.Bakker W, Imbernon M, Salinas CG, Moro Chao DH, Hassouna R, Morel C, Martin C, Leger C, Denis RGP, Castel J, Peter A, Heni M, Maetzler W, Nielsen HS, Duquenne M, Schwaninger M, Lundh S, Johan Hogendorf WF, Gangarossa G, Secher A, Hecksher-Sørensen J, Pedersen TÅ, Prevot V, Luquet S Cell reports, 2022 (41), 111698 | | Submitted Externally | 36417883 | Published | |
| Simultaneous loss of TSC1 and DEPDC5 in skeletal and cardiac muscles produces early-onset myopathy and cardiac dysfunction associated with oxidative damage and SQSTM1/p62 accumulation.Cho CS, Kim Y, Park SR, Kim B, Davis C, Hwang I, Brooks SV, Lee JH, Kim M Autophagy, 2022 (18), 2303 - 2322 | | Submitted Externally | 34964695 | Published | |
| Human iPSC-derived cerebral organoids model features of Leigh syndrome and reveal abnormal corticogenesis.Romero-Morales AI, Robertson GL, Rastogi A, Rasmussen ML, Temuri H, McElroy GS, Chakrabarty RP, Hsu L, Almonacid PM, Millis BA, Chandel NS, Cartailler JP, Gama V Development (Cambridge, England), 2022 (149) | | Submitted Externally | 35792828 | Published | |
| | | Submitted Externally | 35868363 | Published | |
| | | Submitted Externally | 35912645 | Published | |
| The mitochondrial NAD kinase functions as a major metabolic regulator upon increased energy demand.Kim H, Fu Z, Yang Z, Song Z, Shamsa EH, Yumnamcha T, Sun S, Liu W, Ibrahim AS, Qi NR, Zhang R, Zhang K Molecular metabolism, 2022 (64), 101562 | | Submitted Externally | 35944895 | Published | |
| High fat diet blunts stress-induced hypophagia and activation of Glp1r dorsal lateral septum neurons in male but not in female mice.Bales MB, Centanni SW, Luchsinger JR, Fathi P, Biddinger JE, Le TDV, Nwaba KG, Paldrmic IM, Winder DG, Ayala JE Molecular metabolism, 2022 (64), 101571 | | Submitted Externally | 35953023 | Published | |
| A Single Nucleotide Polymorphism in SH2B3/LNK Promotes Hypertension Development and Renal Damage.Alexander MR, Hank S, Dale BL, Himmel L, Zhong X, Smart CD, Fehrenbach DJ, Chen Y, Prabakaran N, Tirado B, Centrella M, Ao M, Du L, Shyr Y, Levy D, Madhur MS Circulation research, 2022 (131), 731 - 747 | | Submitted Externally | 36169218 | Published | |
| Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease.Wong HY, Sheng Q, Hesterberg AB, Croessmann S, Rios BL, Giri K, Jackson J, Miranda AX, Watkins E, Schaffer KR, Donahue M, Winkler E, Penson DF, Smith JA, Herrell SD, Luckenbaugh AN, Barocas DA, Kim YJ, Graves D, Giannico GA, Rathmell JC, Park BH, Gordetsky JB, Hurley PJ Nature communications, 2022 (13), 6036 | | Submitted Externally | 36229464 | Published | |
| | | Submitted Externally | 36361847 | Published | |
| Rab11FIP1-deficient mice develop spontaneous inflammation and show increased susceptibility to colon damage.Rathan-Kumar S, Roland JT, Momoh M, Goldstein A, Lapierre LA, Manning E, Mitchell L, Norman J, Kaji I, Goldenring JR American journal of physiology. Gastrointestinal and liver physiology, 2022 (323), G239 - G254 | | Submitted Externally | 35819177 | Published | |
| Glucagon-like peptide-1 receptor differentially controls mossy cell activity across the dentate gyrus longitudinal axis.Steiner A, Owen BM, Bauer JP, Seanez L, Kwon S, Biddinger JE, Huffman R, Ayala JE, Nobis WP, Lewis AS Hippocampus, REFERENCES, 2022 | | Submitted Externally | 36063105 | Published | |
| | | Submitted Externally | 36102198 | Published | |
| | | Submitted Externally | 36114012 | Published | |
| Promoting validation and cross-phylogenetic integration in model organism research.Cheng KC, Burdine RD, Dickinson ME, Ekker SC, Lin AY, Lloyd KCK, Lutz CM, MacRae CA, Morrison JH, O'Connor DH, Postlethwait JH, Rogers CD, Sanchez S, Simpson JH, Talbot WS, Wallace DC, Weimer JM, Bellen HJ Disease models & mechanisms, 2022 (15) | | Submitted Externally | 36125045 | Published | |
| | | Submitted Externally | 35584728 | Published | |
| | | Submitted Externally | 35792967 | Published | |
| | | Submitted Externally | 35856563 | Published | |
| | | Submitted Externally | 35926490 | Published | |
| EGFR-mediated activation of adipose tissue macrophages promotes obesity and insulin resistance.Cao S, Pan Y, Tang J, Terker AS, Arroyo Ornelas JP, Jin GN, Wang Y, Niu A, Fan X, Wang S, Harris RC, Zhang MZ Nature communications, 2022 (13), 4684 | | Submitted Externally | 35948530 | Published | |
| | | Submitted Externally | 35984867 | Published | |
| | | Submitted Externally | 36009019 | Published | |
| | | Submitted Externally | 36042284 | Published | |
| | | Submitted Externally | 36044273 | Published | |
| | | Submitted Externally | 36079709 | Published | |
| | | Submitted Externally | 35550884 | Published | |
| Excess Growth Hormone Alters the Male Mouse Gut Microbiome in an Age-dependent Manner.Jensen EA, Young JA, Jackson Z, Busken J, Kuhn J, Onusko M, Carroll RK, List EO, Brown JM, Kopchick JJ, Murphy ER, Berryman DE Endocrinology, 2022 (163) | | Submitted Externally | 35617141 | Published | |
| Discovery of a small-molecule inhibitor of the TRIP8b-HCN interaction with efficacy in neurons.Han Y, Iyamu ID, Clutter MR, Mishra RK, Lyman KA, Zhou C, Michailidis I, Xia MY, Sharma H, Luan CH, Schiltz GE, Chetkovich DM The Journal of biological chemistry, 2022 (298), 102069 | | Submitted Externally | 35623388 | Published | |
| | | Submitted Externally | 35802245 | Published | |
| | | Submitted Externally | 35816045 | Published | |
| Podocytes derived from human induced pluripotent stem cells: characterization, comparison, and modeling of diabetic kidney disease.Bejoy J, Farry JM, Peek JL, Cabatu MC, Williams FM, Welch RC, Qian ES, Woodard LE Stem cell research & therapy, 2022 (13), 355 | | Submitted Externally | 35883199 | Published | |
| Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice.Ahuja P, Ng CF, Pang BPS, Chan WS, Tse MCL, Bi X, Kwan HR, Brobst D, Herlea-Pana O, Yang X, Du G, Saengnipanthkul S, Noh HL, Jiao B, Kim JK, Lee CW, Ye K, Chan CB Autophagy, 2022 (18), 1367 - 1384 | | Submitted Externally | 34689722 | Published | |
| | | Submitted Externally | 35227826 | Published | |
| Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis.Rom O, Liu Y, Finney AC, Ghrayeb A, Zhao Y, Shukha Y, Wang L, Rajanayake KK, Das S, Rashdan NA, Weissman N, Delgadillo L, Wen B, Garcia-Barrio MT, Aviram M, Kevil CG, Yurdagul A, Pattillo CB, Zhang J, Sun D, Hayek T, Gottlieb E, Mor I, Chen YE Redox biology, 2022 (52), 102313 | | Submitted Externally | 35447412 | Published | |
| Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis.Weiss A, Murdoch CC, Edmonds KA, Jordan MR, Monteith AJ, Perera YR, Rodríguez Nassif AM, Petoletti AM, Beavers WN, Munneke MJ, Drury SL, Krystofiak ES, Thalluri K, Wu H, Kruse ARS, DiMarchi RD, Caprioli RM, Spraggins JM, Chazin WJ, Giedroc DP, Skaar EP Cell, 2022 (185), 2148 - 2163.e27 | | Submitted Externally | 35584702 | Published | |
| | | Submitted Externally | 35708710 | Published | |
| Metabolic Impact of MKP-2 Upregulation in Obesity Promotes Insulin Resistance and Fatty Liver Disease.Fernando S, Sellers J, Smith S, Bhogoju S, Junkins S, Welch M, Willoughby O, Ghimire N, Secunda C, Barmanova M, Kumer SC, Min K, Lawan A Nutrients, 2022 (14) | | Submitted Externally | 35745205 | Published | |
| Serum Protein Exposure Activates a Core Regulatory Program Driving Human Proximal Tubule Injury.Lidberg KA, Muthusamy S, Adil M, Mahadeo A, Yang J, Patel RS, Wang L, Bammler TK, Reichel J, Yeung CK, Himmelfarb J, Kelly EJ, Akilesh S Journal of the American Society of Nephrology : JASN, 2022 (33), 949 - 965 | | Submitted Externally | 35197326 | Published | |
| Worsening Postural Tachycardia Syndrome Is Associated With Increased Glucose-Dependent Insulinotropic Polypeptide Secretion.Breier NC, Paranjape SY, Scudder S, Mehr SE, Diedrich A, Flynn CR, Okamoto LE, Hartmann B, Gasbjerg LS, Shibao CA Hypertension (Dallas, Tex. : 1979), 2022 (79), e89 - e99 | | Submitted Externally | 35232225 | Published | |
| | | Submitted Externally | 35339750 | Published | |
| | | Submitted Externally | 35477775 | Published | |
| Cyclooxygenase-2 in adipose tissue macrophages limits adipose tissue dysfunction in obese mice.Pan Y, Cao S, Tang J, Arroyo JP, Terker AS, Wang Y, Niu A, Fan X, Wang S, Zhang Y, Jiang M, Wasserman DH, Zhang MZ, Harris RC The Journal of clinical investigation, 2022 (132) | | Submitted Externally | 35499079 | Published | |
| Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction.Clayton DB, Tong CMC, Li B, Taylor AS, De S, Mason MD, Dudley AG, Davidoff O, Kobayashi H, Haase VH American journal of physiology. Renal physiology, 2022 | | Submitted Externally | 35499237 | Published | |
| | | Submitted Externally | 35501599 | Published | |
| MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors.Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choksi YA, Palin K, Piazuelo MB, Washington MK, Lau KS, Goettel JA, Hiebert SW, Short SP, Williams CS JCI insight, 2022 (7) | | Submitted Externally | 35503250 | Published | |
| Dichotomous role of miR193b-3p in diabetic foot ulcers maintains inhibition of healing and suppression of tumor formation.Marjanovic J, Ramirez HA, Jozic I, Stone RC, Wikramanayake TC, Head CR, Abdo Abujamra B, Ojeh N, Kirsner RS, Lev-Tov H, Pastar I, Tomic-Canic M Science translational medicine, 2022 (14), eabg8397 | | Submitted Externally | 35544594 | Published | |
| Liraglutide increases islet Ca2+ oscillation frequency and insulin secretion by activating hyperpolarization-activated cyclic nucleotide-gated channels.Zaborska KE, Jordan KL, Thorson AS, Dadi PK, Schaub CM, Nakhe AY, Dickerson MT, Lynch JC, Weiss AJ, Dobson JR, Jacobson DA Diabetes, obesity & metabolism, REFERENCES, 2022 | | Submitted Externally | 35546791 | Published | |
| Cine gastric MRI reveals altered Gut-Brain Axis in Functional Dyspepsia: gastric motility is linked with brainstem-cortical fMRI connectivity.Sclocco R, Fisher H, Staley R, Han K, Mendez A, Bolender A, Coll-Font J, Kettner NW, Nguyen C, Kuo B, Napadow V Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, REFERENCES, 2022, e14396 | | Submitted Externally | 35560690 | Published | |
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| Reactive oxygen species-degradable polythioketal urethane foam dressings to promote porcine skin wound repair.Patil P, Russo KA, McCune JT, Pollins AC, Cottam MA, Dollinger BR, DeJulius CR, Gupta MK, D'Arcy R, Colazo JM, Yu F, Bezold MG, Martin JR, Cardwell NL, Davidson JM, Thompson CM, Barbul A, Hasty AH, Guelcher SA, Duvall CL Science translational medicine, 2022 (14), eabm6586 | | Submitted Externally | 35442705 | Published | |
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| Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux.Bedi S, Morris J, Shah A, Hart RC, Jerome WG, Aller SG, Tang C, Vaisar T, Bornfeldt KE, Segrest JP, Heinecke JW, Davidson WS Journal of lipid research, 2022 (63), 100168 | | Submitted Externally | 35051413 | Published | |
| Montmorencytart cherry supplementation improved markers of glucose homeostasis but has modest effects on indicators of gut health in mice fed a Western diet.Kaur A, Ojo BA, Wong SY, Alake SE, Pastor M, Rassi GD, Lin D, Smith BJ, Lucas EA Nutrition research (New York, N.Y.), 2022 (99), 66 - 77 | | Submitted Externally | 35101747 | Published | |
| Short Term Changes in Dietary Fat Content and Metformin Treatment During Lactation Impact Milk Composition and Mammary Gland Morphology.Carlson Z, Hafner H, Habbal NE, Harman E, Liu S, Botezatu N, Alharastani M, Rivet C, Reynolds H, Both N, Sun H, Bridges D, Gregg B Journal of mammary gland biology and neoplasia, 2022 (27), 1 - 18 | | Submitted Externally | 35137304 | Published | |
| Natriuretic Peptide Oligomers Cause Proarrhythmic Metabolic and Electrophysiological Effects in Atrial Myocytes.Yang Z, Subati T, Kim K, Murphy MB, Dougherty OP, Christopher IL, Van Amburg JC, Woodall KK, Barnett JV, Murray KT Circulation. Arrhythmia and electrophysiology, 2022 (15), e010636 | | Submitted Externally | 35212578 | Published | |
| KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation.Jiang Z, Elsarrag SZ, Duan Q, LaGory EL, Wang Z, Alexanian M, McMahon S, Rulifson IC, Winchester S, Wang Y, Vaisse C, Brown JD, Quattrocelli M, Lin CY, Haldar SM Science advances, 2022 (8), eabj2917 | | Submitted Externally | 35263131 | Published | |
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| Catalase, a therapeutic target in the reversal of estrogen-mediated aging.Elliot SJ, Catanuto P, Pereira-Simon S, Xia X, Pastar I, Thaller S, Head CR, Stojadinovic O, Tomic-Canic M, Glassberg MK Molecular therapy : the journal of the American Society of Gene Therapy, 2022 (30), 947 - 962 | | Submitted Externally | 34174444 | Published | |
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| Enhanced phosphate absorption in intestinal epithelial cell-specific NHE3 knockout mice.Xue J, Thomas L, Murali SK, Levi M, Fenton RA, Dominguez Rieg JA, Rieg T Acta physiologica (Oxford, England), REFERENCES, 2022 (234), e13756 | | Submitted Externally | 34978760 | Published | |
| The Purkinje-myocardial junction is the anatomic origin of ventricular arrhythmia in CPVT.Blackwell DJ, Faggioni M, Wleklinski MJ, Gomez-Hurtado N, Venkataraman R, Gibbs CE, Baudenbacher FJ, Gong S, Fishman GI, Boyle PM, Pfeifer K, Knollmann BC JCI insight, 2022 (7) | | Submitted Externally | 34990403 | Published | |
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| Label-free imaging of non-deparaffinized sections of the human kidney to determine tissue quality and signatures of disease.Sabo AR, Winfree S, Bledsoe SB, Phillips CL, Lingeman JE, Eadon MT, Williams JC, El-Achkar TM Physiological reports, References, 2022 (10), e15167 | | Submitted Externally | 35133089 | Published | |
| Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance.Skovsø S, Panzhinskiy E, Kolic J, Cen HH, Dionne DA, Dai XQ, Sharma RB, Elghazi L, Ellis CE, Faulkner K, Marcil SAM, Overby P, Noursadeghi N, Hutchinson D, Hu X, Li H, Modi H, Wildi JS, Botezelli JD, Noh HL, Suk S, Gablaski B, Bautista A, Kim R, Cras-Méneur C, Flibotte S, Sinha S, Luciani DS, Nislow C, Rideout EJ, Cytrynbaum EN, Kim JK, Bernal-Mizrachi E, Alonso LC, MacDonald PE, Johnson JD Nature communications, 2022 (13), 735 | | Submitted Externally | 35136059 | Published | |
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| DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis.Laut CL, Leasure CS, Pi H, Carlin SM, Chu ML, Hillebrand GH, Lin HK, Yi XI, Stauff DL, Skaar EP Infection and immunity, 2022 (90), e0056021 | | Submitted Externally | 34748369 | Published | |
| Endothelial c-Myc knockout enhances diet-induced liver inflammation and fibrosis.Qi Y, Qadir MMF, Hastreiter AA, Fock RA, Machi JF, Morales AA, Wang Y, Meng Z, Rodrigues CO FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022 (36), e22077 | | Submitted Externally | 34878671 | Published | |
| Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images.Harris CR, McKinley ET, Roland JT, Liu Q, Shrubsole MJ, Lau KS, Coffey RJ, Wrobel J, Vandekar SN Bioinformatics (Oxford, England), 2022 | | Submitted Externally | 34983062 | Published | |
| | | Submitted Externally | 34984584 | Published | |
| Single cell transcriptomic landscape of diabetic foot ulcers.Theocharidis G, Thomas BE, Sarkar D, Mumme HL, Pilcher WJR, Dwivedi B, Sandoval-Schaefer T, Sîrbulescu RF, Kafanas A, Mezghani I, Wang P, Lobao A, Vlachos IS, Dash B, Hsia HC, Horsley V, Bhasin SS, Veves A, Bhasin M Nature communications, 2022 (13), 181 | | Submitted Externally | 35013299 | Published | |
| Inhibition of 11ß-Hydroxysteroid dehydrogenase-1 with AZD4017 in patients with nonalcoholic steatohepatitis or nonalcoholic fatty liver disease: A randomized, double-blind, placebo-controlled, phase II study.Yadav Y, Dunagan K, Khot R, Venkatesh SK, Port J, Galderisi A, Cobelli C, Wegner C, Basu A, Carter R, Basu R Diabetes, obesity & metabolism, REFERENCES, 2022 | | Submitted Externally | 35014156 | Published | |
| Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity.Çakir I, Hadley CK, Pan PL, Bagchi RA, Ghamari-Langroudi M, Porter DT, Wang Q, Litt MJ, Jana S, Hagen S, Lee P, White A, Lin JD, McKinsey TA, Cone RD Nature metabolism, 2022 (4), 44 - 59 | | Submitted Externally | 35039672 | Published | |
| Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers.Montaniel KRC, Bucher M, Phillips EA, Li C, Sullivan EL, Kievit P, Rugonyi S, Nathanielsz PW, Maloyan A Journal of developmental origins of health and disease, 2022, 1 - 14 | | Submitted Externally | 35068408 | Published | |
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| Helicobacter pylori actively suppresses innate immune nucleic acid receptors.Dooyema SDR, Noto JM, Wroblewski LE, Piazuelo MB, Krishna U, Suarez G, Romero-Gallo J, Delgado AG, Peek RM Gut microbes, 2022 (14), 2105102 | | Submitted Externally | 35905376 | Published | |
| Differential effects of Akkermansia-enriched fecal microbiota transplant on energy balance in female mice on high-fat diet.Acharya KD, Friedline RH, Ward DV, Graham ME, Tauer L, Zheng D, Hu X, de Vos WM, McCormick BA, Kim JK, Tetel MJ Frontiers in endocrinology, 2022 (13), 1010806 | | Submitted Externally | 36387852 | Published | |
| Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the "obesity paradox".Vick LV, Collins CP, Khuat LT, Wang Z, Dunai C, Aguilar EG, Stoffel K, Yendamuri S, Smith R, Mukherjee S, Barbi J, Canter RJ, Monjazeb AM, Murphy WJ Frontiers in immunology, 2022 (13), 1012016 | | Submitted Externally | 36776393 | Published | |
| Oropharyngeal Squamous Cell Carcinoma Morphology and Subtypes by Human Papillomavirus Type and by 16 Lineages and Sublineages.Lewis JS, Mirabello L, Liu P, Wang X, Dupont WD, Plummer WD, Pinheiro M, Yeager M, Boland JF, Cullen M, Steinberg M, Bass S, Mehrad M, O'Boyle C, Lin M, Faden DL, Lang-Kuhs KA Head and neck pathology, 2021 (15), 1089 - 1098 | | Submitted Externally | 33797697 | Published | |
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| BAd-CRISPR: Inducible gene knockout in interscapular brown adipose tissue of adult mice.Romanelli SM, Lewis KT, Nishii A, Rupp AC, Li Z, Mori H, Schill RL, Learman BS, Rhodes CJ, MacDougald OA The Journal of biological chemistry, 2021 (297), 101402 | | Submitted Externally | 34774798 | Published | |
| Antibiofilm Activity of Human Milk Oligosaccharides against Multidrug Resistant and Susceptible Isolates of Acinetobacter baumannii.Spicer SK, Moore RE, Lu J, Guevara MA, Marshall DR, Manning SD, Damo SM, Townsend SD, Gaddy JA ACS infectious diseases, 2021 (7), 3254 - 3263 | | Submitted Externally | 34812035 | Published | |
| Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and Outcomes in Patients Hospitalized for COVID-19.Pan M, Vasbinder A, Anderson E, Catalan T, Shadid HR, Berlin H, Padalia K, O'Hayer P, Meloche C, Azam TU, Khaleel I, Michaud E, Blakely P, Bitar A, Huang Y, Zhao L, Pop-Busui R, Loosen SH, Chalkias A, Tacke F, Giamarellos-Bourboulis EJ, Reiser J, Eugen-Olsen J, Hayek SS, Journal of the American Heart Association, 2021 (10), e023535 | | Submitted Externally | 34889102 | Published | |
| Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.Chen B, Scurrah CR, McKinley ET, Simmons AJ, Ramirez-Solano MA, Zhu X, Markham NO, Heiser CN, Vega PN, Rolong A, Kim H, Sheng Q, Drewes JL, Zhou Y, Southard-Smith AN, Xu Y, Ro J, Jones AL, Revetta F, Berry LD, Niitsu H, Islam M, Pelka K, Hofree M, Chen JH, Sarkizova S, Ng K, Giannakis M, Boland GM, Aguirre AJ, Anderson AC, Rozenblatt-Rosen O, Regev A, Hacohen N, Kawasaki K, Sato T, Goettel JA, Grady WM, Zheng W, Washington MK, Cai Q, Sears CL, Goldenring JR, Franklin JL, Su T, Huh WJ, Vandekar S Cell, 2021 (184), 6262 - 6280.e26 | | Submitted Externally | 34910928 | Published | |
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| Depleting hypothalamic somatostatinergic neurons recapitulates diabetic phenotypes in mouse brain, bone marrow, adipose and retina.Huang C, Rosencrans RF, Bugescu R, Vieira CP, Hu P, Adu-Agyeiwaah Y, Gamble KL, Longhini ALF, Fuller PM, Leinninger GM, Grant MB Diabetologia, 2021 (64), 2575 - 2588 | | Submitted Externally | 34430981 | Published | |
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| CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis.Polosukhina D, Singh K, Asim M, Barry DP, Allaman MM, Hardbower DM, Piazuelo MB, Washington MK, Gobert AP, Wilson KT, Coburn LA Oncogene, 2021 (40), 6540 - 6546 | | Submitted Externally | 34625710 | Published | |
| Comparative impact of dietary carbohydrates on the liver transcriptome in two strains of mice.Chi Y, Youn DY, Xiaoli AM, Liu L, Qiu Y, Kurland IJ, Pessin JB, Yang F, Pessin JE Physiological genomics, 2021 (53), 456 - 472 | | Submitted Externally | 34643091 | Published | |
| Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity.Bock F, Elias BC, Dong X, Parekh DV, Mernaugh G, Viquez OM, Hassan A, Amara VR, Liu J, Brown KL, Terker AS, Chiusa M, Gewin LS, Fogo AB, Brakebusch CH, Pozzi A, Zent R The Journal of cell biology, 2021 (220) | | Submitted Externally | 34647970 | Published | |
| | | Submitted Externally | 34648185 | Published | |
| mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits.Maksymetz J, Byun NE, Luessen DJ, Li B, Barry RL, Gore JC, Niswender CM, Lindsley CW, Joffe ME, Conn PJ Cell reports, 2021 (37), 109950 | | Submitted Externally | 34731619 | Published | |
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| Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.Boland BB, Laker RC, O'Brien S, Sitaula S, Sermadiras I, Nielsen JC, Barkholt P, Roostalu U, Hecksher-Sørensen J, Sejthen SR, Thorbek DD, Suckow A, Burmeister N, Oldham S, Will S, Howard VG, Gill BM, Newton P, Naylor J, Hornigold DC, Austin J, Lantier L, McGuinness OP, Trevaskis JL, Grimsby JS, Rhodes CJ Molecular metabolism, 2021 (55), 101392 | | Submitted Externally | 34781035 | Published | |
| Differences in Inflammation, Treatment, and Outcomes Between Black and Non-Black Patients Hospitalized for COVID-19: A Prospective Cohort Study.Azam TU, Berlin H, Anderson E, Pan M, Shadid HR, Padalia K, O'Hayer P, Meloche C, Feroze R, Michaud E, Launius C, Blakely P, Bitar A, Willer C, Pop-Busui R, Carethers JM, Hayek SS The American journal of medicine, 2021 | | Submitted Externally | 34793753 | Published | |
| Progression of diabetes is associated with changes in the ileal transcriptome and ileal-colon morphology in the UC Davis Type 2 Diabetes Mellitus rat.Piccolo BD, Graham JL, Kang P, Randolph CE, Shankar K, Yeruva L, Fox R, Robeson MS, Moody B, LeRoith T, Stanhope KL, Adams SH, Havel PJ Physiological reports, 2021 (9), e15102 | | Submitted Externally | 34806320 | Published | |
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| CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP Nature communications, 2021 (12), 6931 | | Submitted Externally | 34836963 | Published | |
| | | Submitted Externally | 33845201 | Published | |
| Growth hormone secretagogue receptor-1a mediates ghrelin's effects on attenuating tumour-induced loss of muscle strength but not muscle mass.Liu H, Zang P, Lee II, Anderson B, Christiani A, Strait-Bodey L, Breckheimer BA, Storie M, Tewnion A, Krumm K, Li T, Irwin B, Garcia JM Journal of cachexia, sarcopenia and muscle, 2021 (12), 1280 - 1295 | | Submitted Externally | 34264027 | Published | |
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| Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice.Brewer CM, Nelson BR, Wakenight P, Collins SJ, Okamura DM, Dong XR, Mahoney WM, McKenna A, Shendure J, Timms A, Millen KJ, Majesky MW Developmental cell, 2021 (56), 2722 - 2740.e6 | | Submitted Externally | 34610329 | Published | |
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| Sex-biased islet ß cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males.Walker EM, Cha J, Tong X, Guo M, Liu JH, Yu S, Iacovazzo D, Mauvais-Jarvis F, Flanagan SE, Korbonits M, Stafford J, Jacobson DA, Stein R Cell reports, 2021 (37), 109813 | | Submitted Externally | 34644565 | Published | |
| | | Submitted Externally | 34654741 | Published | |
| Determining the pharmacologic window of bisphosphonates that mitigates severe injury-induced osteoporosis and muscle calcification, while preserving fracture repair.Saito M, Moore-Lotridge SN, Uppuganti S, Egawa S, Yoshii T, Robinette JP, Posey SL, Gibson BHY, Cole HA, Hawley GD, Guelcher SA, Tanner SB, McCarthy JR, Nyman JS, Schoenecker JG Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021 | | Submitted Externally | 34719727 | Published | |
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| Activating mGlu3 Metabotropic Glutamate Receptors Rescues Schizophrenia-like Cognitive Deficits Through Metaplastic Adaptations Within the Hippocampus.Dogra S, Stansley BJ, Xiang Z, Qian W, Gogliotti RG, Nicoletti F, Lindsley CW, Niswender CM, Joffe ME, Conn PJ Biological Psychiatry, 2021 (90), 385 - 398 | | Submitted Externally | 33965197 | Published | |
| Group B Streptococcus cpsE Is Required for Serotype V Capsule Production and Aids in Biofilm Formation and Ascending Infection of the Reproductive Tract during Pregnancy.Noble K, Lu J, Guevara MA, Doster RS, Chambers SA, Rogers LM, Moore RE, Spicer SK, Eastman AJ, Francis JD, Manning SD, Rajagopal L, Aronoff DM, Townsend SD, Gaddy JA ACS infectious diseases, 2021 (7), 2686 - 2696 | | Submitted Externally | 34076405 | Published | |
| Adipocyte-Specific Deletion of Lamin A/C Largely Models Human Familial Partial Lipodystrophy Type 2.Corsa CAS, Walsh CM, Bagchi DP, Foss Freitas MC, Li Z, Hardij J, Granger K, Mori H, Schill RL, Lewis KT, Maung JN, Azaria RD, Rothberg AE, Oral EA, MacDougald OA Diabetes, 2021 (70), 1970 - 1984 | | Submitted Externally | 34088712 | Published | |
| A systematic review and meta-analysis of cell-based interventions in experimental diabetic kidney disease.Hickson LJ, Abedalqader T, Ben-Bernard G, Mondy JM, Bian X, Conley SM, Zhu X, Herrmann SM, Kukla A, Lorenz EC, Kim SR, Thorsteinsdottir B, Lerman LO, Murad MH Stem cells translational medicine, 2021 (10), 1304 - 1319 | | Submitted Externally | 34106528 | Published | |
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| Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice.O'Reilly J, Ono-Moore KD, Chintapalli SV, Rutkowsky JM, Tolentino T, Lloyd KCK, Olfert IM, Adams SH Physiological reports, 2021 (9), e15031 | | Submitted Externally | 34545692 | Published | |
| Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling.Hennessey C, Keogh CE, Barboza M, Brust-Mascher I, Knotts TA, Sladek JA, Pusceddu MM, Stokes P, Rabasa G, Honeycutt M, Walsh O, Nichols R, Reardon C, Gareau MG Infection and immunity, 2021 (89), e0005921 | | Submitted Externally | 33820817 | Published | |
| | | Submitted Externally | 33839113 | Published | |
| Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens.Cai W, Zhang X, Batista TM, García-Martín R, Softic S, Wang G, Ramirez AK, Konishi M, O'Neill BT, Kim JH, Kim JK, Kahn CR Diabetes, 2021 (70), 1857 - 1873 | | Submitted Externally | 34031123 | Published | |
| Deep-Learning-Driven Quantification of Interstitial Fibrosis in Digitized Kidney Biopsies.Zheng Y, Cassol CA, Jung S, Veerapaneni D, Chitalia VC, Ren KYM, Bellur SS, Boor P, Barisoni LM, Waikar SS, Betke M, Kolachalama VB The American journal of pathology, 2021 (191), 1442 - 1453 | | Submitted Externally | 34033750 | Published | |
| Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic ß-cell dysfunction and loss.Koike S, Hsu MF, Bettaieb A, Chu B, Matsumoto N, Morisseau C, Havel PJ, Huising MO, Hammock BD, Haj FG Free radical biology & medicine, 2021 (172), 48 - 57 | | Submitted Externally | 34038767 | Published | |
| Creation and validation of 3D-printed head molds for stereotaxic injections of neonatal mouse brains.Chervonski E, Brockman AA, Khurana R, Chen Y, Greenberg S, Hay MS, Luo Y, Miller J, Patelis D, Whitney SK, Walker M, Ihrie RA Journal of neuroscience methods, 2021 (360), 109255 | | Submitted Externally | 34139267 | Published | |
| Molecular topography of an entire nervous system.Taylor SR, Santpere G, Weinreb A, Barrett A, Reilly MB, Xu C, Varol E, Oikonomou P, Glenwinkel L, McWhirter R, Poff A, Basavaraju M, Rafi I, Yemini E, Cook SJ, Abrams A, Vidal B, Cros C, Tavazoie S, Sestan N, Hammarlund M, Hobert O, Miller DM Cell, 2021 (184), 4329 - 4347.e23 | | Submitted Externally | 34237253 | Published | |
| | | Submitted Externally | 34237302 | Published | |
| Mutation of the 5'-untranslated region stem-loop mRNA structure reduces type I collagen deposition and arterial stiffness in male obese mice.Ramirez-Perez FI, Woodford ML, Morales-Quinones M, Grunewald ZI, Cabral-Amador FJ, Yoshida T, Brenner DA, Manrique-Acevedo C, Martinez-Lemus LA, Chandrasekar B, Padilla J American journal of physiology. Heart and circulatory physiology, 2021 (321), H435 - H445 | | Submitted Externally | 34242094 | Published | |
| TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced ß-cell proliferation.Altman MK, Schaub CM, Dadi PK, Dickerson MT, Zaborska KE, Nakhe AY, Graff SM, Galletta TJ, Amarnath G, Thorson AS, Gu G, Jacobson DA Development (Cambridge, England), 2021 (148) | | Submitted Externally | 34345920 | Published | |
| Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice.Bozadjieva-Kramer N, Shin JH, Shao Y, Gutierrez-Aguilar R, Li Z, Heppner KM, Chiang S, Vargo SG, Granger K, Sandoval DA, MacDougald OA, Seeley RJ Nature communications, 2021 (12), 4768 | | Submitted Externally | 34362888 | Published | |
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| Circulating Osteopontin Levels and Outcomes in Patients Hospitalized for COVID-19.Hayek SS, Roderburg C, Blakely P, Launius C, Eugen-Olsen J, Tacke F, Ktena S, Keitel V, Luedde M, Giamarellos-Bourboulis EJ, Luedde T, Loosen SH Journal of clinical medicine, 2021 (10) | | Submitted Externally | 34501358 | Published | |
| | | Submitted Externally | 33883214 | Published | |
| Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis.Ovadia C, Sajous J, Seed PT, Patel K, Williamson NJ, Attilakos G, Azzaroli F, Bacq Y, Batsry L, Broom K, Brun-Furrer R, Bull L, Chambers J, Cui Y, Ding M, Dixon PH, Estiú MC, Gardiner FW, Geenes V, Grymowicz M, Günaydin B, Hague WM, Haslinger C, Hu Y, Indraccolo U, Juusela A, Kane SC, Kebapcilar A, Kebapcilar L, Kohari K, Kondrackiene J, Koster MPH, Lee RH, Liu X, Locatelli A, Macias RIR, Madazli R, Majewska A, Maksym K, Marathe JA, Morton A, Oudijk MA, Öztekin D, Peek MJ, Shennan AH, Tribe RM, The lancet. Gastroenterology & hepatology, 2021 (6), 547 - 558 | | Submitted Externally | 33915090 | Published | |
| | | Submitted Externally | 33930756 | Published | |
| Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice.Ono-Moore KD, Olfert IM, Rutkowsky JM, Chintapalli SV, Willis BJ, Blackburn ML, Williams DK, O'Reilly J, Tolentino T, Lloyd KCK, Adams SH American journal of physiology. Endocrinology and metabolism, 2021 (321), E63 - E79 | | Submitted Externally | 33969704 | Published | |
| On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice.Blackburn ML, Wankhade UD, Ono-Moore KD, Chintapalli SV, Fox R, Rutkowsky JM, Willis BJ, Tolentino T, Lloyd KCK, Adams SH American journal of physiology. Endocrinology and metabolism, 2021 (321), E47 - E62 | | Submitted Externally | 33969705 | Published | |
| Phenotypic Heterogeneity and Metastasis of Breast Cancer Cells.Hapach LA, Carey SP, Schwager SC, Taufalele PV, Wang W, Mosier JA, Ortiz-Otero N, McArdle TJ, Goldblatt ZE, Lampi MC, Bordeleau F, Marshall JR, Richardson IM, Li J, King MR, Reinhart-King CA Cancer research, 2021 (81), 3649 - 3663 | | Submitted Externally | 33975882 | Published | |
| Guidelines for the measurement of vascular function and structure in isolated arteries and veins.Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC American journal of physiology. Heart and circulatory physiology, 2021 (321), H77 - H111 | | Submitted Externally | 33989082 | Published | |
| Diet-dependent sex differences in the response to vertical sleeve gastrectomy.Hutch CR, Stelmak D, Kanke M, Koch-Laskowski K, Cummings B, Griffin C, Leix K, Sethupathy P, Singer K, Sandoval DA American journal of physiology. Endocrinology and metabolism, 2021 (321), E11 - E23 | | Submitted Externally | 33998293 | Published | |
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| Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis.Liu Y, Zhao Y, Shukha Y, Lu H, Wang L, Liu Z, Liu C, Zhao Y, Wang H, Zhao G, Liang W, Fan Y, Chang L, Yurdagul A, Pattillo CB, Orr AW, Aviram M, Wen B, Garcia-Barrio MT, Zhang J, Liu W, Sun D, Hayek T, Chen YE, Rom O Cell reports, 2021 (36), 109420 | | Submitted Externally | 34320345 | Published | |
| Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II.Melchior JT, Street SE, Vaisar T, Hart R, Jerome J, Kuklenyik Z, Clouet-Foraison N, Thornock C, Bedi S, Shah AS, Segrest JP, Heinecke JW, Davidson WS Journal of lipid research, 2021 (62), 100099 | | Submitted Externally | 34324889 | Published | |
| Distinct Changes in Gut Microbiota Are Associated with Estradiol-Mediated Protection from Diet-Induced Obesity in Female Mice.Acharya KD, Noh HL, Graham ME, Suk S, Friedline RH, Gomez CC, Parakoyi AER, Chen J, Kim JK, Tetel MJ Metabolites, 2021 (11) | | Submitted Externally | 34436440 | Published | |
| | | Submitted Externally | 33757993 | Published | |
| Effects of Totum-63 on glucose homeostasis and postprandial glycemia: a translational study.Chavanelle V, Otero YF, Le Joubioux F, Ripoche D, Bargetto M, Vluggens A, Montaurier C, Pickering G, Ducheix G, Dubray C, Dualé C, Boulliau S, Macian N, Marceau G, Sapin V, Dutheil F, Guigas B, Maugard T, Boisseau N, Cazaubiel M, Peltier SL, Sirvent P American journal of physiology. Endocrinology and metabolism, 2021 (320), E1119 - E1137 | | Submitted Externally | 33938234 | Published | |
| Loss of growth hormone signaling in the mouse germline or in adulthood reduces islet mass and alters islet function with notable sex differences.Duran-Ortiz S, Corbin KL, Jahan I, Whitticar NB, Morris SE, Bartholomew AN, Slepchenko KG, West HL, Max Harry IM, List EO, Kopchick JJ, Nunemaker CS American journal of physiology. Endocrinology and metabolism, 2021 (320), E1158 - E1172 | | Submitted Externally | 33938235 | Published | |
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| Mfge8 attenuates human gastric antrum smooth muscle contractions.Li W, Olseen A, Xie Y, Alexandru C, Outland A, Herrera AF, Syder AJ, Wykosky J, Perrino BA Journal of muscle research and cell motility, 2021 (42), 219 - 231 | | Submitted Externally | 34085177 | Published | |
| Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade.Yan C, Saleh N, Yang J, Nebhan CA, Vilgelm AE, Reddy EP, Roland JT, Johnson DB, Chen SC, Shattuck-Brandt RL, Ayers GD, Richmond A Molecular cancer, 2021 (20), 85 | | Submitted Externally | 34092233 | Published | |
| Microscopic examination of spatial transcriptome using Seq-Scope.Cho CS, Xi J, Si Y, Park SR, Hsu JE, Kim M, Jun G, Kang HM, Lee JH Cell, 2021 (184), 3559 - 3572.e22 | | Submitted Externally | 34115981 | Published | |
| | | Submitted Externally | 34156032 | Published | |
| Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue.Qu J, Fourman S, Fitzgerald M, Liu M, Nair S, Oses-Prieto J, Burlingame A, Morris JH, Davidson WS, Tso P, Bhargava A Scientific reports, 2021 (11), 13289 | | Submitted Externally | 34168225 | Published | |
| A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity.Geisler CE, Ghimire S, Bruggink SM, Miller KE, Weninger SN, Kronenfeld JM, Yoshino J, Klein S, Duca FA, Renquist BJ Cell reports, 2021 (35), 109301 | | Submitted Externally | 34192532 | Published | |
| Sex-Based Differences in Cardiac Gene Expression and Function in BDNF Val66Met Mice.Negron M, Kristensen J, Nguyen VT, Gansereit LE, Raucci FJ, Chariker JL, Heck A, Brula I, Kitchen G, Awgulewitsch CP, Zhong L, Rouchka EC, Banga S, Galindo CL International journal of molecular sciences, 2021 (22) | | Submitted Externally | 34210092 | Published | |
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| High Dietary Fat Consumption Impairs Axonal Mitochondrial Function In Vivo.Sajic M, Rumora AE, Kanhai AA, Dentoni G, Varatharajah S, Casey C, Brown RDR, Peters F, Hinder LM, Savelieff MG, Feldman EL, Smith KJ The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021 (41), 4321 - 4334 | | Submitted Externally | 33785643 | Published | |
| Gene expression profiles of diabetic kidney disease and neuropathy in eNOS knockout mice: Predictors of pathology and RAS blockade effects.Eid SA, Hinder LM, Zhang H, Eksi R, Nair V, Eddy S, Eichinger F, Park M, Saha J, Berthier CC, Jagadish HV, Guan Y, Pennathur S, Hur J, Kretzler M, Feldman EL, Brosius FC FASEB journal : official publication of the Federation of American Societies for Experimental Biology, REFERENCES, 2021 (35), e21467 | | Submitted Externally | 33788970 | Published | |
| Cell-programmed nutrient partitioning in the tumour microenvironment.Reinfeld BI, Madden MZ, Wolf MM, Chytil A, Bader JE, Patterson AR, Sugiura A, Cohen AS, Ali A, Do BT, Muir A, Lewis CA, Hongo RA, Young KL, Brown RE, Todd VM, Huffstater T, Abraham A, O'Neil RT, Wilson MH, Xin F, Tantawy MN, Merryman WD, Johnson RW, Williams CS, Mason EF, Mason FM, Beckermann KE, Vander Heiden MG, Manning HC, Rathmell JC, Rathmell WK Nature, 2021 (593), 282 - 288 | | Submitted Externally | 33828302 | Published | |
| Effect of High Dietary Sodium Intake in Patients With Postural Tachycardia Syndrome.Garland EM, Gamboa A, Nwazue VC, Celedonio JE, Paranjape SY, Black BK, Okamoto LE, Shibao CA, Biaggioni I, Robertson D, Diedrich A, Dupont WD, Raj SR Journal of the American College of Cardiology, 2021 (77), 2174 - 2184 | | Submitted Externally | 33926653 | Published | |
| Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler.Woodley CM, Romer AS, Wang J, Guarnaccia AD, Elion DL, Maxwell JN, Guerrazzi K, McCann TS, Popay TM, Matlock BK, Flaherty DK, Lorey SL, Liu Q, Tansey WP, Weissmiller AM Oncogene, 2021 (40), 3593 - 3609 | | Submitted Externally | 33931740 | Published | |
| Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.Haywood NJ, Luk C, Bridge KI, Drozd M, Makava N, Skromna A, Maccannell A, Ozber CH, Warmke N, Wilkinson CG, Watt NT, Koch-Paszkowski J, Teh I, Boyle JH, Smart S, Schneider JE, Yuldasheva NY, Roberts LD, Beech DJ, Sukumar P, Wheatcroft SB, Cubbon RM, Kearney MT EMBO reports, 2021 (22), e50767 | | Submitted Externally | 33934497 | Published | |
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| AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells.Kook S, Wang P, Meng S, Jetter CS, Sucre JMS, Benjamin JT, Gokey JJ, Hanby HA, Jaume A, Goetzl L, Marks MS, Guttentag SH Proceedings of the National Academy of Sciences of the United States of America, 2021 (118) | | Submitted Externally | 33990468 | Published | |
| Adipocyte P2Y14 receptors play a key role in regulating whole-body glucose and lipid homeostasis.Jain S, Pydi SP, Jung YH, Scortichini M, Kesner EL, Karcz TP, Cook DN, Gavrilova O, Wess J, Jacobson KA JCI insight, 2021 (6) | | Submitted Externally | 34027896 | Published | |
| In vivo screen identifies a SIK inhibitor that induces ß cell proliferation through a transient UPR.Charbord J, Ren L, Sharma RB, Johansson A, Ågren R, Chu L, Tworus D, Schulz N, Charbord P, Stewart AF, Wang P, Alonso LC, Andersson O Nature metabolism, 2021 (3), 682 - 700 | | Submitted Externally | 34031592 | Published | |
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| ARCGHR Neurons Regulate Muscle Glucose Uptake.de Lima JBM, Debarba LK, Rupp AC, Qi N, Ubah C, Khan M, Didyuk O, Ayyar I, Koch M, Sandoval DA, Sadagurski M Cells, 2021 (10) | | Submitted Externally | 34063647 | Published | |
| Hepatocyte Small Heterodimer Partner Mediates Sex-Specific Effects on Triglyceride Metabolism via Androgen Receptor in Male Mice.Palmisano BT, Zhu L, Litts B, Burman A, Yu S, Neuman JC, Anozie U, Luu TN, Edington EM, Stafford JM Metabolites, 2021 (11) | | Submitted Externally | 34065318 | Published | |
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| A requirement for p120-catenin in the metastasis of invasive ductal breast cancer.Kurley SJ, Tischler V, Bierie B, Novitskiy SV, Noske A, Varga Z, Zürrer-Härdi U, Brandt S, Carnahan RH, Cook RS, Muller WJ, Richmond A, Reynolds AB Journal of cell science, 2021 (134) | | Submitted Externally | 33097605 | Published | |
| Kidney epithelial targeted mitochondrial transcription factor A deficiency results in progressive mitochondrial depletion associated with severe cystic disease.Ishii K, Kobayashi H, Taguchi K, Guan N, Li A, Tong C, Davidoff O, Tran PV, Sharma M, Chandel NS, Kapp ME, Fogo AB, Brooks CR, Haase VH Kidney international, 2021 (99), 657 - 670 | | Submitted Externally | 33159962 | Published | |
| A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor-Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention.Wei SC, Meijers WC, Axelrod ML, Anang NAS, Screever EM, Wescott EC, Johnson DB, Whitley E, Lehmann L, Courand PY, Mancuso JJ, Himmel LE, Lebrun-Vignes B, Wleklinski MJ, Knollmann BC, Srinivasan J, Li Y, Atolagbe OT, Rao X, Zhao Y, Wang J, Ehrlich LIR, Sharma P, Salem JE, Balko JM, Moslehi JJ, Allison JP Cancer discovery, 2021 (11), 614 - 625 | | Submitted Externally | 33257470 | Published | |
| Sox10-cre BAC transgenes reveal temporal restriction of mesenchymal cranial neural crest and identify glandular Sox10 expression.Deal KK, Rosebrock JC, Eeds AM, DeKeyser JL, Musser MA, Ireland SJ, May-Zhang AA, Buehler DP, Southard-Smith EM Developmental biology, 2021 (471), 119 - 137 | | Submitted Externally | 33316258 | Published | |
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| Injection Reactions after Administration of Sustained-release Meloxicam to BALB/cJ, C57BL/6J, and Crl:CD1(ICR) Mice.Fuetsch SR, Stewart LA, Imai DM, Beckett LA, Li Y, Lloyd KCK, Grimsrud KN Journal of the American Association for Laboratory Animal Science : JAALAS, 2021 (60), 176 - 183 | | Submitted Externally | 33402233 | Published | |
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| Importance of Adipose Tissue NAD+ Biology in Regulating Metabolic Flexibility.Franczyk MP, Qi N, Stromsdorfer KL, Li C, Yamaguchi S, Itoh H, Yoshino M, Sasaki Y, Brookheart RT, Finck BN, DeBosch BJ, Klein S, Yoshino J Endocrinology, 2021 (162) | | Submitted Externally | 33543238 | Published | |
| Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.Healey DCC, Cephus JY, Barone SM, Chowdhury NU, Dahunsi DO, Madden MZ, Ye X, Yu X, Olszewski K, Young K, Gerriets VA, Siska PJ, Dworski R, Hemler J, Locasale JW, Poyurovsky MV, Peebles RS, Irish JM, Newcomb DC, Rathmell JC Journal of immunology (Baltimore, Md. : 1950), 2021 (206), 1127 - 1139 | | Submitted Externally | 33558372 | Published | |
| | | Submitted Externally | 33693631 | Published | |
| Vagus nerve stimulation activates two distinct neuroimmune circuits converging in the spleen to protect mice from kidney injury.Tanaka S, Abe C, Abbott SBG, Zheng S, Yamaoka Y, Lipsey JE, Skrypnyk NI, Yao J, Inoue T, Nash WT, Stornetta DS, Rosin DL, Stornetta RL, Guyenet PG, Okusa MD Proceedings of the National Academy of Sciences of the United States of America, 2021 (118) | | Submitted Externally | 33737395 | Published | |
| Maternal exposure to high-fat diet during pregnancy and lactation predisposes normal weight offspring mice to develop hepatic inflammation and insulin resistance.Saengnipanthkul S, Noh HL, Friedline RH, Suk S, Choi S, Acosta NK, Tran DA, Hu X, Inashima K, Kim AM, Lee KW, Kim JK Physiological reports, 2021 (9), e14811 | | Submitted Externally | 33769706 | Published | |
| | | Submitted Externally | 33769710 | Published | |
| Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant.Leslie JL, Jenior ML, Vendrov KC, Standke AK, Barron MR, O'Brien TJ, Unverdorben L, Thaprawat P, Bergin IL, Schloss PD, Young VB mBio, 2021 (12) | | Submitted Externally | 33785619 | Published | |
| | | Submitted Externally | 32917985 | Published | |
| Combinatorial Transcriptional Profiling of Mouse and Human Enteric Neurons Identifies Shared and Disparate Subtypes In Situ.May-Zhang AA, Tycksen E, Southard-Smith AN, Deal KK, Benthal JT, Buehler DP, Adam M, Simmons AJ, Monaghan JR, Matlock BK, Flaherty DK, Potter SS, Lau KS, Southard-Smith EM Gastroenterology, 2021 (160), 755 - 770.e26 | | Submitted Externally | 33010250 | Published | |
| Characterization of viral insulins reveals white adipose tissue-specific effects in mice.Chrudinová M, Moreau F, Noh HL, Páníková T, Žáková L, Friedline RH, Valenzuela FA, Kim JK, Jirácek J, Kahn CR, Altindis E Molecular metabolism, 2021 (44), 101121 | | Submitted Externally | 33220491 | Published | |
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| Molecular characterization of the human kidney interstitium in health and disease.Barwinska D, El-Achkar TM, Ferreira RM, Syed F, Cheng YH, Winfree S, Ferkowicz MJ, Hato T, Collins KS, Dunn KW, Kelly KJ, Sutton TA, Rovin BH, Parikh SV, Phillips CL, Dagher PC, Eadon MT, Science advances, 2021 (7) | | Submitted Externally | 33568476 | Published | |
| Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis.Fan L, Sweet DR, Prosdocimo DA, Vinayachandran V, Chan ER, Zhang R, Ilkayeva O, Lu Y, Keerthy KS, Booth CE, Newgard CB, Jain MK The Journal of clinical investigation, 2021 (131) | | Submitted Externally | 33586679 | Published | |
| A distinct repertoire of cancer-associated fibroblasts is enriched in cribriform prostate cancer.Hesterberg AB, Rios BL, Wolf EM, Tubbs C, Wong HY, Schaffer KR, Lotan TL, Giannico GA, Gordetsky JB, Hurley PJ The journal of pathology. Clinical research, References, 2021 | | Submitted Externally | 33600062 | Published | |
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| A Pilot Study Comparing the Effects of Consuming 100% Orange Juice or Sucrose-Sweetened Beverage on Risk Factors for Cardiometabolic Disease in Women.Price CA, Medici V, Nunez MV, Lee V, Sigala DM, Benyam Y, Keim NL, Mason AE, Chen SY, Parenti M, Slupsky C, Epel ES, Havel PJ, Stanhope KL Nutrients, 2021 (13) | | Submitted Externally | 33652807 | Published | |
| Differential effects of minocycline on microvascular complications in murine models of type 1 and type 2 diabetes.Eid SA, O'Brien PD, Hinder LM, Hayes JM, Mendelson FE, Zhang H, Narayanan S, Abcouwer SF, Brosius FC, Pennathur S, Savelieff MG, Feldman EL Journal of translational science, 2021 (7) | | Submitted Externally | 33868719 | Published | |
| Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.Benjamin JT, Plosa EJ, Sucre JM, van der Meer R, Dave S, Gutor S, Nichols DS, Gulleman PM, Jetter CS, Han W, Xin M, Dinella PC, Catanzarite A, Kook S, Dolma K, Lal CV, Gaggar A, Blalock JE, Newcomb DC, Richmond BW, Kropski JA, Young LR, Guttentag SH, Blackwell TS The Journal of clinical investigation, 2021 (131) | | Submitted Externally | 33108351 | Published | |
| Myelin as a regulator of development of the microbiota-gut-brain axis.Keogh CE, Kim DHJ, Pusceddu MM, Knotts TA, Rabasa G, Sladek JA, Hsieh MT, Honeycutt M, Brust-Mascher I, Barboza M, Gareau MG Brain, behavior, and immunity, 2021 (91), 437 - 450 | | Submitted Externally | 33157256 | Published | |
| Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers.Jackson MA, Patel SS, Yu F, Cottam MA, Glass EB, Hoogenboezem EN, Fletcher RB, Dollinger BR, Patil P, Liu DD, Kelly IB, Bedingfield SK, King AR, Miles RE, Hasty AM, Giorgio TD, Duvall CL Biomaterials, 2021 (268), 120528 | | Submitted Externally | 33285438 | Published | |
| | | Submitted Externally | 33324864 | Published | |
| Impact of WIN site inhibitor on the WDR5 interactome.Guarnaccia AD, Rose KL, Wang J, Zhao B, Popay TM, Wang CE, Guerrazzi K, Hill S, Woodley CM, Hansen TJ, Lorey SL, Shaw JG, Payne WG, Weissmiller AM, Olejniczak ET, Fesik SW, Liu Q, Tansey WP Cell reports, 2021 (34), 108636 | | Submitted Externally | 33472061 | Published | |
| | | Submitted Externally | 33575288 | Published | |
| SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease.Deguise MO, Pileggi C, De Repentigny Y, Beauvais A, Tierney A, Chehade L, Michaud J, Llavero-Hurtado M, Lamont D, Atrih A, Wishart TM, Gillingwater TH, Schneider BL, Harper ME, Parson SH, Kothary R Cellular and molecular gastroenterology and hepatology, 2021 (12), 354 - 377.e3 | | Submitted Externally | 33545428 | Published | |
| Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N The Journal of biological chemistry, 2021 (296), 100482 | | Submitted Externally | 33647317 | Published | |
| | | Submitted Externally | 33839158 | Published | |
| Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving ß-Cell Maturation.Sanavia T, Huang C, Manduchi E, Xu Y, Dadi PK, Potter LA, Jacobson DA, Di Camillo B, Magnuson MA, Stoeckert CJ, Gu G Frontiers in cell and developmental biology, 2021 (9), 648791 | | Submitted Externally | 34017831 | Published | |
| Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation.Sarode GV, Neier K, Shibata NM, Shen Y, Goncharov DA, Goncharova EA, Mazi TA, Joshi N, Settles ML, LaSalle JM, Medici V Cellular and molecular gastroenterology and hepatology, 2021 (12), 1457 - 1477 | | Submitted Externally | 34098115 | Published | |
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| Expressing the Human Cholesteryl Ester Transfer Protein Minigene Improves Diet-Induced Fatty Liver and Insulin Resistance in Female Mice.Zhu L, An J, Chinnarasu S, Luu T, Pettway YD, Fahey K, Litts B, Kim HH, Flynn CR, Linton MF, Stafford JM Frontiers in physiology, 2021 (12), 799096 | | Submitted Externally | 35082691 | Published | |
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| HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression.Anthony SR, Guarnieri A, Lanzillotta L, Gozdiff A, Green LC, O'Grady K, Helsley RN, Owens Iii AP, Tranter M Adipocyte, 2020 (9), 335 - 345 | | Submitted Externally | 32713230 | Published | |
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| SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in ß Cells.Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, Kapp ME, Fasolino M, Morgan A, Dai C, Saunders DC, Bottino R, Aramandla R, Jenkins R, Stein R, Kaestner KH, Vahedi G, Brissova M, Powers AC Cell Metabolism, 2020 (32), 1028 - 1040.e4 | | Submitted Externally | 33207245 | Published | |
| Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome.Rom O, Liu Y, Liu Z, Zhao Y, Wu J, Ghrayeb A, Villacorta L, Fan Y, Chang L, Wang L, Liu C, Yang D, Song J, Rech JC, Guo Y, Wang H, Zhao G, Liang W, Koike Y, Lu H, Koike T, Hayek T, Pennathur S, Xi C, Wen B, Sun D, Garcia-Barrio MT, Aviram M, Gottlieb E, Mor I, Liu W, Zhang J, Chen YE Science translational medicine, 2020 (12) | | Submitted Externally | 33268508 | Published | |
| Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity.Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, Miller BC, Juneja VR, Nguyen TH, Joshi S, Yao CH, Yoon H, Sage PT, LaFleur MW, Trombley JD, Jacobson CA, Maliga Z, Gygi SP, Sorger PK, Rabinowitz JD, Sharpe AH, Haigis MC Cell, 2020 (183), 1848 - 1866.e26 | | Submitted Externally | 33301708 | Published | |
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| Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance.Wang G, Yu Y, Cai W, Batista TM, Suk S, Noh HL, Hirshman M, Nigro P, Li ME, Softic S, Goodyear L, Kim JK, Kahn CR Diabetes, 2020 (69), 2294 - 2309 | | Submitted Externally | 32868340 | Published | |
| Synergistic effects of fructose and glucose on lipoprotein risk factors for cardiovascular disease in young adults.Hieronimus B, Medici V, Bremer AA, Lee V, Nunez MV, Sigala DM, Keim NL, Havel PJ, Stanhope KL Metabolism: clinical and experimental, 2020 (112), 154356 | | Submitted Externally | 32916151 | Published | |
| TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions.Cohen AS, Li J, Hight MR, McKinley E, Fu A, Payne A, Liu Y, Zhang D, Xie Q, Bai M, Ayers GD, Tantawy MN, Smith JA, Revetta F, Washington MK, Shi C, Merchant N, Manning HC Clinical cancer research : an official journal of the American Association for Cancer Research, 2020 (26), 5914 - 5925 | | Submitted Externally | 32933996 | Published | |
| Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI.Azam TU, Shadid HR, Blakely P, O'Hayer P, Berlin H, Pan M, Zhao P, Zhao L, Pennathur S, Pop-Busui R, Altintas I, Tingleff J, Stauning MA, Andersen O, Adami ME, Solomonidi N, Tsilika M, Tober-Lau P, Arnaoutoglou E, Keitel V, Tacke F, Chalkias A, Loosen SH, Giamarellos-Bourboulis EJ, Eugen-Olsen J, Reiser J, Hayek SS, Journal of the American Society of Nephrology : JASN, 2020 (31), 2725 - 2735 | | Submitted Externally | 32963090 | Published | |
| | | Submitted Externally | 33080135 | Published | |
| A zebrafish functional genomics model to investigate the role of human A20 variants in vivo.Cultrone D, Zammit NW, Self E, Postert B, Han JZR, Bailey J, Warren J, Croucher DR, Kikuchi K, Bogdanovic O, Chtanova T, Hesselson D, Grey ST Scientific reports, 2020 (10), 19085 | | Submitted Externally | 33154446 | Published | |
| | | Submitted Externally | 33207675 | Published | |
| PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans.Rojas-Rodriguez R, Ziegler R, DeSouza T, Majid S, Madore AS, Amir N, Pace VA, Nachreiner D, Alfego D, Mathew J, Leung K, Moore Simas TA, Corvera S Science translational medicine, 2020 (12) | | Submitted Externally | 33239385 | Published | |
| Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation.Khuat LT, Le CT, Pai CS, Shields-Cutler RR, Holtan SG, Rashidi A, Parker SL, Knights D, Luna JI, Dunai C, Wang Z, Sturgill IR, Stoffel KM, Merleev AA, More SK, Maverakis E, Raybould HE, Chen M, Canter RJ, Monjazeb AM, Dave M, Ferrara JLM, Levine JE, Longo DL, Abedi M, Blazar BR, Murphy WJ Science translational medicine, 2020 (12) | | Submitted Externally | 33239390 | Published | |
| Dysregulated bile acid receptor-mediated signaling and IL-17A induction are implicated in diet-associated hepatic health and cognitive function.Jena PK, Sheng L, Nguyen M, Di Lucente J, Hu Y, Li Y, Maezawa I, Jin LW, Wan YY Biomarker research, 2020 (8), 59 | | Submitted Externally | 33292701 | Published | |
| Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome.Limbrick EM, Graf M, Derewacz DK, Nguyen F, Spraggins JM, Wieland M, Ynigez-Gutierrez AE, Reisman BJ, Zinshteyn B, McCulloch KM, Iverson TM, Green R, Wilson DN, Bachmann BO Journal of the American Chemical Society, 2020 (142), 18369 - 18377 | | Submitted Externally | 32709196 | Published | |
| | | Submitted Externally | 32755435 | Published | |
| TRAF3IP2 (TRAF3 Interacting Protein 2) Mediates Obesity-Associated Vascular Insulin Resistance and Dysfunction in Male Mice.Grunewald ZI, Ramirez-Perez FI, Woodford ML, Morales-Quinones M, Mejia S, Manrique-Acevedo C, Siebenlist U, Martinez-Lemus LA, Chandrasekar B, Padilla J Hypertension (Dallas, Tex. : 1979), 2020 (76), 1319 - 1329 | | Submitted Externally | 32829657 | Published | |
| | | Submitted Externally | 33008490 | Published | |
| Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer.Hoover AA, Hufnagel DH, Harris W, Bullock K, Glass EB, Liu E, Barham W, Crispens MA, Khabele D, Giorgio TD, Wilson AJ, Yull FE BMC cancer, 2020 (20), 970 | | Submitted Externally | 33028251 | Published | |
| Insulin-sensitizing effects of vitamin D repletion mediated by adipocyte vitamin D receptor: Studies in humans and mice.Lontchi-Yimagou E, Kang S, Goyal A, Zhang K, You JY, Carey M, Jain S, Bhansali S, Kehlenbrink S, Guo P, Rosen ED, Kishore P, Hawkins M Molecular metabolism, 2020 (42), 101095 | | Submitted Externally | 33045433 | Published | |
| Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease.Mello A, Hsu MF, Koike S, Chu B, Cheng J, Yang J, Morisseau C, Torok NJ, Hammock BD, Haj FG Cellular and molecular gastroenterology and hepatology, 2020 (11), 815 - 830 | | Submitted Externally | 33068774 | Published | |
| | | Submitted Externally | 33076257 | Published | |
| Short-term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue.Dommerholt MB, Blankestijn M, Vieira-Lara MA, van Dijk TH, Wolters H, Koster MH, Gerding A, van Os RP, Bloks VW, Bakker BM, Kruit JK, Jonker JW The FEBS journal, References, 2020 | | Submitted Externally | 33089625 | Published | |
| Differential Effects of Empagliflozin on Microvascular Complications in Murine Models of Type 1 and Type 2 Diabetes.Eid SA, O'Brien PD, Hinder LM, Hayes JM, Mendelson FE, Zhang H, Zeng L, Kretzler K, Narayanan S, Abcouwer SF, Brosius Iii FC, Pennathur S, Savelieff MG, Feldman EL Biology, 2020 (9) | | Submitted Externally | 33105667 | Published | |
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| Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction.Bagchi DP, Li Z, Corsa CA, Hardij J, Mori H, Learman BS, Lewis KT, Schill RL, Romanelli SM, MacDougald OA Molecular metabolism, 2020 (39), 100992 | | Submitted Externally | 32325263 | Published | |
| Kidney Histopathology and Prediction of Kidney Failure: A Retrospective Cohort Study.Eadon MT, Schwantes-An TH, Phillips CL, Roberts AR, Greene CV, Hallab A, Hart KJ, Lipp SN, Perez-Ledezma C, Omar KO, Kelly KJ, Moe SM, Dagher PC, El-Achkar TM, Moorthi RN American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020 (76), 350 - 360 | | Submitted Externally | 32336487 | Published | |
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| A murine model of pediatric inflammatory bowel disease causes microbiota-gut-brain axis deficits in adulthood.Salvo E, Stokes P, Keogh CE, Brust-Mascher I, Hennessey C, Knotts TA, Sladek JA, Rude KM, Swedek M, Rabasa G, Gareau MG American journal of physiology. Gastrointestinal and liver physiology, 2020 (319), G361 - G374 | | Submitted Externally | 32726162 | Published | |
| Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action.Thielen LA, Chen J, Jing G, Moukha-Chafiq O, Xu G, Jo S, Grayson TB, Lu B, Li P, Augelli-Szafran CE, Suto MJ, Kanke M, Sethupathy P, Kim JK, Shalev A Cell Metabolism, 2020 (32), 353 - 365.e8 | | Submitted Externally | 32726606 | Published | |
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| Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis.Abdul Y, Li W, Ward R, Abdelsaid M, Hafez S, Dong G, Jamil S, Wolf V, Johnson MH, Fagan SC, Ergul A Translational stroke research, 2020 | | Submitted Externally | 32875455 | Published | |
| | | Submitted Externally | 32913355 | Published | |
| Wnt/ß-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells.Bagchi DP, Nishii A, Li Z, DelProposto JB, Corsa CA, Mori H, Hardij J, Learman BS, Lumeng CN, MacDougald OA Molecular metabolism, 2020 (42), 101078 | | Submitted Externally | 32919095 | Published | |
| Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption.Shah A, Dagdeviren S, Lewandowski JP, Schmider AB, Ricci-Blair EM, Natarajan N, Hundal H, Noh HL, Friedline RH, Vidoudez C, Kim JK, Wagers AJ, Soberman RJ, Lee RT iScience, 2020 (23), 101521 | | Submitted Externally | 32927265 | Published | |
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| a2A-adrenergic heteroreceptors are required for stress-induced reinstatement of cocaine conditioned place preference.Perez RE, Basu A, Nabit BP, Harris NA, Folkes OM, Patel S, Gilsbach R, Hein L, Winder DG Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020 (45), 1473 - 1481 | | Submitted Externally | 32074627 | Published | |
| Reciprocity Between Skeletal Muscle AMPK Deletion and Insulin Action in Diet-Induced Obese Mice.Lantier L, Williams AS, Williams IM, Guerin A, Bracy DP, Goelzer M, Foretz M, Viollet B, Hughey CC, Wasserman DH Diabetes, 2020 (69), 1636 - 1649 | | Submitted Externally | 32439824 | Published | |
| Potential positive and negative consequences of ZnT8 inhibition.Syring KE, Bosma KJ, Goleva SB, Singh K, Oeser JK, Lopez CA, Skaar EP, McGuinness OP, Davis LK, Powell DR, O'Brien RM The Journal of endocrinology, 2020 (246), 189 - 205 | | Submitted Externally | 32485672 | Published | |
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| Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids.Vilgelm AE, Bergdorf K, Wolf M, Bharti V, Shattuck-Brandt R, Blevins A, Jones C, Phifer C, Lee M, Lowe C, Hongo R, Boyd K, Netterville J, Rohde S, Idrees K, Bauer JA, Westover D, Reinfeld B, Baregamian N, Richmond A, Rathmell WK, Lee E, McDonald OG, Weiss VL iScience, 2020 (23), 101408 | | Submitted Externally | 32771978 | Published | |
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| Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr-/- mice.Tao H, Huang J, Yancey PG, Yermalitsky V, Blakemore JL, Zhang Y, Ding L, Zagol-Ikapitte I, Ye F, Amarnath V, Boutaud O, Oates JA, Roberts LJ, Davies SS, Linton MF Nature communications, 2020 (11), 4084 | | Submitted Externally | 32796843 | Published | |
| Metastatic Melanoma Patient-Derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition.Shattuck-Brandt RL, Chen SC, Murray E, Johnson CA, Crandall H, O'Neal JF, Al-Rohil RN, Nebhan CA, Bharti V, Dahlman KB, Ayers GD, Yan C, Kelley MC, Kauffmann RM, Hooks M, Grau A, Johnson DB, Vilgelm AE, Richmond A Clinical cancer research : an official journal of the American Association for Cancer Research, 2020 (26), 3803 - 3818 | | Submitted Externally | 32234759 | Published | |
| | | Submitted Externally | 32259599 | Published | |
| Mesenteric arterial dysfunction in the UC Davis Type 2 Diabetes Mellitus rat model is dependent on pre-diabetic versus diabetic status and is sexually dimorphic.Shaligram S, Akther F, Razan MR, Graham JL, Roglans N, Alegret M, Parsa AG, Stanhope KL, Havel PJ, Rahimian R European journal of pharmacology, 2020 (879), 173089 | | Submitted Externally | 32320701 | Published | |
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| Hepatic NADH reductive stress underlies common variation in metabolic traits.Goodman RP, Markhard AL, Shah H, Sharma R, Skinner OS, Clish CB, Deik A, Patgiri A, Hsu YH, Masia R, Noh HL, Suk S, Goldberger O, Hirschhorn JN, Yellen G, Kim JK, Mootha VK Nature, 2020 (583), 122 - 126 | | Submitted Externally | 32461692 | Published | |
| Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy.Zhao Y, Chang Z, Zhao G, Lu H, Xiong W, Liang W, Wang H, Villacorta L, Garcia-Barrio MT, Zhu T, Guo Y, Fan Y, Chang L, Schopfer FJ, Freeman BA, Zhang J, Chen YE Cardiovascular drugs and therapy, 2020 | | Submitted Externally | 32671602 | Published | |
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| Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis.Habermann AC, Gutierrez AJ, Bui LT, Yahn SL, Winters NI, Calvi CL, Peter L, Chung MI, Taylor CJ, Jetter C, Raju L, Roberson J, Ding G, Wood L, Sucre JMS, Richmond BW, Serezani AP, McDonnell WJ, Mallal SB, Bacchetta MJ, Loyd JE, Shaver CM, Ware LB, Bremner R, Walia R, Blackwell TS, Banovich NE, Kropski JA Science advances, 2020 (6), eaba1972 | | Submitted Externally | 32832598 | Published | |
| Coregulator Sin3a Promotes Postnatal Murine ß-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response.Yang X, Graff SM, Heiser CN, Ho KH, Chen B, Simmons AJ, Southard-Smith AN, David G, Jacobson DA, Kaverina I, Wright CVE, Lau KS, Gu G Diabetes, 2020 (69), 1219 - 1231 | | Submitted Externally | 32245798 | Published | |
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| Developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure of either parent enhances the risk of necrotizing enterocolitis in neonatal mice.Mokshagundam S, Ding T, Rumph JT, Dallas M, Stephens VR, Osteen KG, Bruner-Tran KL Birth defects research, REFERENCES, 2020 | | Submitted Externally | 32519502 | Published | |
| | | Submitted Externally | 32545722 | Published | |
| Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension.Prinsen JK, Kannankeril PJ, Sidorova TN, Yermalitskaya LV, Boutaud O, Zagol-Ikapitte I, Barnett JV, Murphy MB, Subati T, Stark JM, Christopher IL, Jafarian-Kerman SR, Saleh MA, Norlander AE, Loperena R, Atkinson JB, Fogo AB, Luther JM, Amarnath V, Davies SS, Kirabo A, Madhur MS, Harrison DG, Murray KT JACC. Basic to translational science, 2020 (5), 602 - 615 | | Submitted Externally | 32613146 | Published | |
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| Neuronal modulation of hepatic lipid accumulation induced by bingelike drinking.Ibars M, Maier MT, Yulyaningsih E, Perez L, Cheang R, Vilhelmsson A, Louie SM, Wegner SA, Yuan X, Eltzschig HK, Hopf FW, Nomura DK, Koliwad SK, Xu AW American journal of physiology. Endocrinology and metabolism, 2020 (318), E655 - E666 | | Submitted Externally | 32045262 | Published | |
| Chronic arsenic exposure impairs adaptive thermogenesis in male C57BL/6J mice.Castriota F, Zushin PH, Sanchez SS, Phillips RV, Hubbard A, Stahl A, Smith MT, Wang JC, La Merrill MA American journal of physiology. Endocrinology and metabolism, 2020 (318), E667 - E677 | | Submitted Externally | 32045263 | Published | |
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| The neuronal (pro)renin receptor and astrocyte inflammation in the central regulation of blood pressure and blood glucose in mice fed a high-fat diet.Worker CJ, Li W, Feng CY, Souza LAC, Gayban AJB, Cooper SG, Afrin S, Romanick S, Ferguson BS, Feng Earley Y American journal of physiology. Endocrinology and metabolism, 2020 (318), E765 - E778 | | Submitted Externally | 32228320 | Published | |
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| Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.Al Batran R, Gopal K, Capozzi ME, Chahade JJ, Saleme B, Tabatabaei-Dakhili SA, Greenwell AA, Niu J, Almutairi M, Byrne NJ, Masson G, Kim R, Eaton F, Mulvihill EE, Garneau L, Masters AR, Desta Z, Velázquez-Martínez CA, Aguer C, Crawford PA, Sutendra G, Campbell JE, Dyck JRB, Ussher JR Cell Metabolism, 2020 (31), 909 - 919.e8 | | Submitted Externally | 32275862 | Published | |
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| A big-data approach to understanding metabolic rate and response to obesity in laboratory mice.Corrigan JK, Ramachandran D, He Y, Palmer CJ, Jurczak MJ, Chen R, Li B, Friedline RH, Kim JK, Ramsey JJ, Lantier L, McGuinness OP, Banks AS eLife, 2020 (9) | | Submitted Externally | 32356724 | Published | |
| Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic ß Cell Proliferation, Function, and Survival.Hu R, Walker E, Huang C, Xu Y, Weng C, Erickson GE, Coldren A, Yang X, Brissova M, Kaverina I, Balamurugan AN, Wright CVE, Li Y, Stein R, Gu G Developmental cell, 2020 (53), 390 - 405.e10 | | Submitted Externally | 32359405 | Published | |
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| Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.Boland ML, Laker RC, Mather K, Nawrocki A, Oldham S, Boland BB, Lewis H, Conway J, Naylor J, Guionaud S, Feigh M, Veidal SS, Lantier L, McGuinness OP, Grimsby J, Rondinone CM, Jermutus L, Larsen MR, Trevaskis JL, Rhodes CJ Nature metabolism, 2020 (2), 413 - 431 | | Submitted Externally | 32478287 | Published | |
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| Development of a novel murine model of lymphatic metastasis.Banan B, Beckstead JA, Dunavant LE, Sohn Y, Adcock JM, Nomura S, Abumrad N, Goldenring JR, Fingleton B Clinical & experimental metastasis, 2020 (37), 247 - 255 | | Submitted Externally | 32052231 | Published | |
| Effects of ERß and ERa on OVX-induced changes in adiposity and insulin resistance.Zidon TM, Padilla J, Fritsche KL, Welly RJ, McCabe LT, Stricklin OE, Frank A, Park Y, Clegg DJ, Lubahn DB, Kanaley JA, Vieira-Potter VJ The Journal of endocrinology, 2020 (245), 165 - 178 | | Submitted Externally | 32053493 | Published | |
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| Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health.Tong X, Dai C, Walker JT, Nair GG, Kennedy A, Carr RM, Hebrok M, Powers AC, Stein R Diabetes, 2020 (69), 342 - 354 | | Submitted Externally | 31836690 | Published | |
| Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi.Butler AA, Graham JL, Stanhope KL, Wong S, King S, Bremer AA, Krauss RM, Hamilton J, Havel PJ Journal of lipid research, 2020 (61), 376 - 386 | | Submitted Externally | 31919051 | Published | |
| Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.Lenk GM, Jafar-Nejad P, Hill SF, Huffman LD, Smolen CE, Wagnon JL, Petit H, Yu W, Ziobro J, Bhatia K, Parent J, Giger RJ, Rigo F, Meisler MH Annals of neurology, 2020 (87), 339 - 346 | | Submitted Externally | 31943325 | Published | |
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| Arrestin domain-containing 3 (Arrdc3) modulates insulin action and glucose metabolism in liver.Batista TM, Dagdeviren S, Carroll SH, Cai W, Melnik VY, Noh HL, Saengnipanthkul S, Kim JK, Kahn CR, Lee RT Proceedings of the National Academy of Sciences of the United States of America, 2020 (117), 6733 - 6740 | | Submitted Externally | 32156724 | Published | |
| Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice.Walker RG, Barrandon O, Poggioli T, Dagdeviren S, Carroll SH, Mills MJ, Mendello KR, Gomez Y, Loffredo FS, Pancoast JR, Macias-Trevino C, Marts C, LeClair KB, Noh HL, Kim T, Banks AS, Kim JK, Cohen DE, Wagers AJ, Melton DA, Lee RT Scientific reports, 2020 (10), 4561 | | Submitted Externally | 32165710 | Published | |
| | | Submitted Externally | 32168364 | Published | |
| Stimulation of water and calcium dynamics in astrocytes with pulsed infrared light.Borrachero-Conejo AI, Adams WR, Saracino E, Mola MG, Wang M, Posati T, Formaggio F, De Bellis M, Frigeri A, Caprini M, Hutchinson MR, Muccini M, Zamboni R, Nicchia GP, Mahadevan-Jansen A, Benfenati V FASEB journal : official publication of the Federation of American Societies for Experimental Biology, REFERENCES, 2020 | | Submitted Externally | 32202681 | Published | |
| The kinetics of glucagon action on the liver during insulin-induced hypoglycemia.Pedersen C, Kraft G, Edgerton DS, Scott M, Farmer B, Smith M, Laneve DC, Williams PE, Moore LM, Cherrington AD American journal of physiology. Endocrinology and metabolism, 2020 | | Submitted Externally | 32208001 | Published | |
| Paraventricular, subparaventricular and periventricular hypothalamic IRS4-expressing neurons are required for normal energy balance.Sutton AK, Gonzalez IE, Sadagurski M, Rajala M, Lu C, Allison MB, Adams JM, Myers MG, White MF, Olson DP Scientific reports, 2020 (10), 5546 | | Submitted Externally | 32218485 | Published | |
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| Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2.Stahl EC, Delgado ER, Alencastro F, LoPresti ST, Wilkinson PD, Roy N, Haschak MJ, Skillen CD, Monga SP, Duncan AW, Brown BN The American journal of pathology, 2020 (190), 372 - 387 | | Submitted Externally | 31843499 | Published | |
| Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding.Cheng W, Gonzalez I, Pan W, Tsang AH, Adams J, Ndoka E, Gordian D, Khoury B, Roelofs K, Evers SS, MacKinnon A, Wu S, Frikke-Schmidt H, Flak JN, Trevaskis JL, Rhodes CJ, Fukada SI, Seeley RJ, Sandoval DA, Olson DP, Blouet C, Myers MG Cell Metabolism, 2020 (31), 301 - 312.e5 | | Submitted Externally | 31955990 | Published | |
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| Modulation of hypothalamic S6K1 and S6K2 alters feeding behavior and systemic glucose metabolism.Tavares MR, Lemes SF, de Fante T, Saenz de Miera C, Pavan ICB, Bezerra RMN, Prada PO, Torsoni MA, Elias CF, Simabuco FM The Journal of endocrinology, 2020 (244), 71 - 82 | | Submitted Externally | 31557728 | Published | |
| Liver-derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis.Watanabe M, Singhal G, Fisher FM, Beck TC, Morgan DA, Socciarelli F, Mather ML, Risi R, Bourke J, Rahmouni K, McGuinness OP, Flier JS, Maratos-Flier E Endocrine, 2020 (67), 95 - 108 | | Submitted Externally | 31728756 | Published | |
| Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction.Williams AS, Koves TR, Davidson MT, Crown SB, Fisher-Wellman KH, Torres MJ, Draper JA, Narowski TM, Slentz DH, Lantier L, Wasserman DH, Grimsrud PA, Muoio DM Cell Metabolism, 2020 (31), 131 - 147.e11 | | Submitted Externally | 31813822 | Published | |
| Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies.Ou YC, Wen X, Johnson CA, Shae D, Ayala OD, Webb JA, Lin EC, DeLapp RC, Boyd KL, Richmond A, Mahadevan-Jansen A, Rafat M, Wilson JT, Balko JM, Tantawy MN, Vilgelm AE, Bardhan R ACS nano, 2020 (14), 651 - 663 | | Submitted Externally | 31851488 | Published | |
| ß1 Integrin regulates adult lung alveolar epithelial cell inflammation.Plosa EJ, Benjamin JT, Sucre JM, Gulleman PM, Gleaves LA, Han W, Kook S, Polosukhin VV, Haake SM, Guttentag SH, Young LR, Pozzi A, Blackwell TS, Zent R JCI insight, 2020 (5) | | Submitted Externally | 31873073 | Published | |
| | | Submitted Externally | 31903723 | Published | |
| Sestrins are evolutionarily conserved mediators of exercise benefits.Kim M, Sujkowski A, Namkoong S, Gu B, Cobb T, Kim B, Kowalsky AH, Cho CS, Semple I, Ro SH, Davis C, Brooks SV, Karin M, Wessells RJ, Lee JH Nature communications, 2020 (11), 190 | | Submitted Externally | 31929512 | Published | |
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| Clinicopathologic correlates of MYD88 L265P mutation and programmed cell death (PD-1) pathway in primary central nervous system lymphoma.Sethi TK, Kovach AE, Grover NS, Huang LC, Lee LA, Rubinstein SM, Wang Y, Morgan DS, Greer JP, Park SI, Ann Thompson-Arildsen M, Yenamandra A, Vnencak-Jones CL, Reddy NM Leukemia & lymphoma, 2019 (60), 2880 - 2889 | | Submitted Externally | 31184237 | Published | |
| | | Submitted Externally | 31526289 | Published | |
| CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high-fat-fed C57BL/6 mice.Hasib A, Hennayake CK, Bracy DP, Bugler-Lamb AR, Lantier L, Khan F, Ashford MLJ, McCrimmon RJ, Wasserman DH, Kang L American journal of physiology. Endocrinology and metabolism, 2019 (317), E973 - E983 | | Submitted Externally | 31550181 | Published | |
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| Postprandial activation of leukocyte-endothelium interaction by fatty acids in the visceral adipose tissue microcirculation.Preston KJ, Rom I, Vrakas C, Landesberg G, Etwebi Z, Muraoka S, Autieri M, Eguchi S, Scalia R FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019 (33), 11993 - 12007 | | Submitted Externally | 31393790 | Published | |
| Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance.Flores A, Argetsinger LS, Stadler LKJ, Malaga AE, Vander PB, DeSantis LC, Joe RM, Cline JM, Keogh JM, Henning E, Barroso I, Mendes de Oliveira E, Chandrashekar G, Clutter ES, Hu Y, Stuckey J, Farooqi IS, Myers MG, Carter-Su C Diabetes, 2019 (68), 2049 - 2062 | | Submitted Externally | 31439647 | Published | |
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| Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell lines.Bryan MR, O'Brien MT, Nordham KD, Rose DIR, Foshage AM, Joshi P, Nitin R, Uhouse MA, Di Pardo A, Zhang Z, Maglione V, Aschner M, Bowman AB Human molecular genetics, 2019 (28), 3825 - 3841 | | Submitted Externally | 31600787 | Published | |
| Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation.Chang E, Hafner H, Varghese M, Griffin C, Clemente J, Islam M, Carlson Z, Zhu A, Hak L, Abrishami S, Gregg B, Singer K Scientific reports, 2019 (9), 16027 | | Submitted Externally | 31690792 | Published | |
| Adipose tissue NAD+ biosynthesis is required for regulating adaptive thermogenesis and whole-body energy homeostasis in mice.Yamaguchi S, Franczyk MP, Chondronikola M, Qi N, Gunawardana SC, Stromsdorfer KL, Porter LC, Wozniak DF, Sasaki Y, Rensing N, Wong M, Piston DW, Klein S, Yoshino J Proceedings of the National Academy of Sciences of the United States of America, 2019 (116), 23822 - 23828 | | Submitted Externally | 31694884 | Published | |
| Peripherally delivered hepatopreferential insulin analog insulin-406 mimics the hypoglycaemia-sparing effect of portal vein human insulin infusion in dogs.Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Madsen P, Kjeldsen TB, Hostrup S, Brand CL, Fledelius C, Nishimura E, Cherrington AD Diabetes, obesity & metabolism, 2019 (21), 2294 - 2304 | | Submitted Externally | 31183936 | Published | |
| | | Submitted Externally | 31213084 | Published | |
| The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity.Ceddia RP, Downey JD, Morrison RD, Kraemer MP, Davis SE, Wu J, Lindsley CW, Yin H, Daniels JS, Breyer RM Prostaglandins & other lipid mediators, 2019 (144), 106353 | | Submitted Externally | 31276827 | Published | |
| | | Submitted Externally | 31306740 | Published | |
| Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice.Rude KM, Pusceddu MM, Keogh CE, Sladek JA, Rabasa G, Miller EN, Sethi S, Keil KP, Pessah IN, Lein PJ, Gareau MG Environmental pollution (Barking, Essex : 1987), 2019 (253), 708 - 721 | | Submitted Externally | 31336350 | Published | |
| Impaired glucose tolerance, glucagon, and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a transporter.Kelly L, Almutairi MM, Kursan S, Pacheco R, Dias-Junior E, Castrop H, Di Fulvio M American journal of physiology. Cell physiology, 2019 (317), C843 - C856 | | Submitted Externally | 31365295 | Published | |
| Fibrotic Encapsulation Is the Dominant Source of Continuous Glucose Monitor Delays.McClatchey PM, McClain ES, Williams IM, Malabanan CM, James FD, Lord PC, Gregory JM, Cliffel DE, Wasserman DH Diabetes, 2019 (68), 1892 - 1901 | | Submitted Externally | 31399432 | Published | |
| Computational Segmentation and Classification of Diabetic Glomerulosclerosis.Ginley B, Lutnick B, Jen KY, Fogo AB, Jain S, Rosenberg A, Walavalkar V, Wilding G, Tomaszewski JE, Yacoub R, Rossi GM, Sarder P Journal of the American Society of Nephrology : JASN, 2019 (30), 1953 - 1967 | | Submitted Externally | 31488606 | Published | |
| | | Submitted Externally | 31509478 | Published | |
| Mss51 deletion enhances muscle metabolism and glucose homeostasis in mice.Rovira Gonzalez YI, Moyer AL, LeTexier NJ, Bratti AD, Feng S, Sun C, Liu T, Mula J, Jha P, Iyer SR, Lovering RM, O'Rourke B, Noh HL, Suk S, Kim JK, Essien Umanah GK, Wagner KR JCI insight, 2019 (4) | | Submitted Externally | 31527314 | Published | |
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| Intestinal basolateral lipid substrate transport is linked to chylomicron secretion and is regulated by apoC-III.Li D, Rodia CN, Johnson ZK, Bae M, Muter A, Heussinger AE, Tambini N, Longo AM, Dong H, Lee JY, Kohan AB Journal of lipid research, 2019 (60), 1503 - 1515 | | Submitted Externally | 31152000 | Published | |
| High Salt Activates CD11c+ Antigen-Presenting Cells via SGK (Serum Glucocorticoid Kinase) 1 to Promote Renal Inflammation and Salt-Sensitive Hypertension.Van Beusecum JP, Barbaro NR, McDowell Z, Aden LA, Xiao L, Pandey AK, Itani HA, Himmel LE, Harrison DG, Kirabo A Hypertension (Dallas, Tex. : 1979), 2019 (74), 555 - 563 | | Submitted Externally | 31280647 | Published | |
| | | Submitted Externally | 31310760 | Published | |
| Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes.Gregory JM, Muldowney JA, Engelhardt BG, Tyree R, Marks-Shulman P, Silver HJ, Donahue EP, Edgerton DS, Winnick JJ Nutrition & diabetes, 2019 (9), 25 | | Submitted Externally | 31474750 | Published | |
| The phage gene wmk is a candidate for male killing by a bacterial endosymbiont.Perlmutter JI, Bordenstein SR, Unckless RL, LePage DP, Metcalf JA, Hill T, Martinez J, Jiggins FM, Bordenstein SR PLoS pathogens, 2019 (15), e1007936 | | Submitted Externally | 31504075 | Published | |
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| Acute Negative Allosteric Modulation of M5 Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with No Effect on Antinociception.Gould RW, Gunter BW, Bubser M, Matthews RT, Teal LB, Ragland MG, Bridges TM, Garrison AT, Winder DG, Lindsley CW, Jones CK ACS chemical neuroscience, 2019 (10), 3740 - 3750 | | Submitted Externally | 31268669 | Published | |
| | | Submitted Externally | 31294621 | Published | |
| A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis.Johnson DB, McDonnell WJ, Gonzalez-Ericsson PI, Al-Rohil RN, Mobley BC, Salem JE, Wang DY, Sanchez V, Wang Y, Chastain CA, Barker K, Liang Y, Warren S, Beechem JM, Menzies AM, Tio M, Long GV, Cohen JV, Guidon AC, O'Hare M, Chandra S, Chowdhary A, Lebrun-Vignes B, Goldinger SM, Rushing EJ, Buchbinder EI, Mallal SA, Shi C, Xu Y, Moslehi JJ, Sanders ME, Sosman JA, Balko JM Nature medicine, 2019 (25), 1243 - 1250 | | Submitted Externally | 31332390 | Published | |
| Hypothalamic mTORC2 is essential for metabolic health and longevity.Chellappa K, Brinkman JA, Mukherjee S, Morrison M, Alotaibi MI, Carbajal KA, Alhadeff AL, Perron IJ, Yao R, Purdy CS, DeFelice DM, Wakai MH, Tomasiewicz J, Lin A, Meyer E, Peng Y, Arriola Apelo SI, Puglielli L, Betley JN, Paschos GK, Baur JA, Lamming DW Aging cell, 2019, e13014 | | Submitted Externally | 31373126 | Published | |
| | | Submitted Externally | 31393852 | Published | |
| Abnormal fatty acid metabolism is a core component of spinal muscular atrophy.Deguise MO, Baranello G, Mastella C, Beauvais A, Michaud J, Leone A, De Amicis R, Battezzati A, Dunham C, Selby K, Warman Chardon J, McMillan HJ, Huang YT, Courtney NL, Mole AJ, Kubinski S, Claus P, Murray LM, Bowerman M, Gillingwater TH, Bertoli S, Parson SH, Kothary R Annals of clinical and translational neurology, 2019 (6), 1519 - 1532 | | Submitted Externally | 31402618 | Published | |
| Muscle-generated BDNF is a sexually dimorphic myokine that controls metabolic flexibility.Yang X, Brobst D, Chan WS, Tse MCL, Herlea-Pana O, Ahuja P, Bi X, Zaw AM, Kwong ZSW, Jia WH, Zhang ZG, Zhang N, Chow SKH, Cheung WH, Louie JCY, Griffin TM, Nong W, Hui JHL, Du GH, Noh HL, Saengnipanthkul S, Chow BKC, Kim JK, Lee CW, Chan CB Science signaling, 2019 (12) | | Submitted Externally | 31409756 | Published | |
| Bcl2-Expressing Quiescent Type B Neural Stem Cells in the Ventricular-Subventricular Zone Are Resistant to Concurrent Temozolomide/X-Irradiation.Cameron BD, Traver G, Roland JT, Brockman AA, Dean D, Johnson L, Boyd K, Ihrie RA, Freeman ML Stem cells (Dayton, Ohio), 2019 | | Submitted Externally | 31430423 | Published | |
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| Substrate Elasticity Governs Differentiation of Renal Tubule Cells in Prolonged Culture.Love HD, Ao M, Jorgensen S, Swearingen L, Ferrell N, Evans R, Gewin L, Harris RC, Zent R, Roy S, Fissell WH Tissue engineering. Part A, 2019 (25), 1013 - 1022 | | Submitted Externally | 30484388 | Published | |
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| A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis.Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM Cell reports, 2019 (28), 773 - 791.e7 | | Submitted Externally | 31315054 | Published | |
| | | Submitted Externally | 31355333 | Published | |
| Sympathetic Denervation of the Common Hepatic Artery Lessens Glucose Intolerance in the Fat- and Fructose-Fed Dog.Kraft G, Vrba A, Scott M, Allen E, Edgerton DS, Williams PE, Vafai SB, Azamian BR, Cherrington AD Diabetes, 2019 (68), 1143 - 1155 | | Submitted Externally | 30936143 | Published | |
| Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue.Prentice BM, Hart NJ, Phillips N, Haliyur R, Judd A, Armandala R, Spraggins JM, Lowe CL, Boyd KL, Stein RW, Wright CV, Norris JL, Powers AC, Brissova M, Caprioli RM Diabetologia, 2019 (62), 1036 - 1047 | | Submitted Externally | 30955045 | Published | |
| | | Submitted Externally | 30965283 | Published | |
| Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates.Butler AA, Zhang J, Price CA, Stevens JR, Graham JL, Stanhope KL, King S, Krauss RM, Bremer AA, Havel PJ The Journal of biological chemistry, 2019 (294), 9706 - 9719 | | Submitted Externally | 30988006 | Published | |
| Role of Leptin in the Association Between Body Adiposity and Persistent Asthma: A Longitudinal Study.Li Z, Leynaert B, Dumas O, Diaz Gil O, Garcia-Aymerich J, Fito Colomer M, Le Moual N, Pison C, Romieu I, Siroux V, Camargo CA, Varraso R, Nadif R Obesity (Silver Spring, Md.), 2019 (27), 894 - 898 | | Submitted Externally | 31004416 | Published | |
| GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity.Hwang I, Jo K, Shin KC, Kim JI, Ji Y, Park YJ, Park J, Jeon YG, Ka S, Suk S, Noh HL, Choe SS, Alfadda AA, Kim JK, Kim S, Kim JB Proceedings of the National Academy of Sciences of the United States of America, 2019 (116), 11936 - 11945 | | Submitted Externally | 31160440 | Published | |
| | | Submitted Externally | 31167964 | Published | |
| XX sex chromosome complement promotes atherosclerosis in mice.AlSiraj Y, Chen X, Thatcher SE, Temel RE, Cai L, Blalock E, Katz W, Ali HM, Petriello M, Deng P, Morris AJ, Wang X, Lusis AJ, Arnold AP, Reue K, Thompson K, Tso P, Cassis LA Nature communications, 2019 (10), 2631 | | Submitted Externally | 31201301 | Published | |
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| Metabolic consequences of cystinuria.Woodard LE, Welch RC, Veach RA, Beckermann TM, Sha F, Weinman EJ, Ikizler TA, Tischfield JA, Sahota A, Wilson MH BMC nephrology, 2019 (20), 227 | | Submitted Externally | 31221135 | Published | |
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| Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice.Luissint AC, Williams HC, Kim W, Flemming S, Azcutia V, Hilgarth RS, Leary MNO, Denning TL, Nusrat A, Parkos CA Mucosal immunology, 2019 (12), 668 - 678 | | Submitted Externally | 30745566 | Published | |
| | | Submitted Externally | 30779633 | Published | |
| Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis.O'Dwyer DN, Ashley SL, Gurczynski SJ, Xia M, Wilke C, Falkowski NR, Norman KC, Arnold KB, Huffnagle GB, Salisbury ML, Han MK, Flaherty KR, White ES, Martinez FJ, Erb-Downward JR, Murray S, Moore BB, Dickson RP American journal of respiratory and critical care medicine, 2019 (199), 1127 - 1138 | | Submitted Externally | 30789747 | Published | |
| | | Submitted Externally | 30850319 | Published | |
| Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition.Toubai T, Fujiwara H, Rossi C, Riwes M, Tamaki H, Zajac C, Liu C, Mathew AV, Byun J, Oravecz-Wilson K, Matsuda I, Sun Y, Peltier D, Wu J, Chen J, Seregin S, Henig I, Kim S, Brabbs S, Pennathur S, Chen G, Reddy P Nature microbiology, 2019 (4), 800 - 812 | | Submitted Externally | 30858572 | Published | |
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| Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice.Zhang K, Guo X, Yan H, Wu Y, Pan Q, Shen JZ, Li X, Chen Y, Li L, Qi Y, Xu Z, Xie W, Zhang W, Threadgill D, He L, Villarreal D, Sun Y, White MF, Zheng H, Guo S Endocrinology, 2019 (160), 1333 - 1347 | | Submitted Externally | 30951171 | Published | |
| G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche.Li Z, Hardij J, Evers SS, Hutch CR, Choi SM, Shao Y, Learman BS, Lewis KT, Schill RL, Mori H, Bagchi DP, Romanelli SM, Kim KS, Bowers E, Griffin C, Seeley RJ, Singer K, Sandoval DA, Rosen CJ, MacDougald OA The Journal of clinical investigation, 2019 (130), 2404 - 2416 | | Submitted Externally | 31063988 | Published | |
| | | Submitted Externally | 31074744 | Published | |
| Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison to GCK-MODY (MODY2).Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ Diabetes, 2019 | | Submitted Externally | 31092478 | Published | |
| A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium.Barupal DK, Zhang Y, Shen T, Fan S, Roberts BS, Fitzgerald P, Wancewicz B, Valdiviez L, Wohlgemuth G, Byram G, Choy YY, Haffner B, Showalter MR, Vaniya A, Bloszies CS, Folz JS, Kind T, Flenniken AM, McKerlie C, Nutter LMJ, Lloyd KC, Fiehn O Metabolites, 2019 (9) | | Submitted Externally | 31121816 | Published | |
| Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis.Ghadieh HE, Russo L, Muturi HT, Ghanem SS, Manaserh IH, Noh HL, Suk S, Kim JK, Hill JW, Najjar SM Metabolism: clinical and experimental, 2019 (93), 33 - 43 | | Submitted Externally | 30664851 | Published | |
| Transcriptional and physiological roles for STAT proteins in leptin action.Pan W, Allison MB, Sabatini P, Rupp A, Adams J, Patterson C, Jones JC, Olson DP, Myers MG Molecular metabolism, 2019 (22), 121 - 131 | | Submitted Externally | 30718218 | Published | |
| Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or ApoC3 RNA interference.Butler AA, Price CA, Graham JL, Stanhope KL, King S, Hung YH, Sethupathy P, Wong S, Hamilton J, Krauss RM, Bremer AA, Havel PJ Journal of lipid research, 2019 (60), 805 - 818 | | Submitted Externally | 30723097 | Published | |
| | | Submitted Externally | 30753113 | Published | |
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| Site-Specific Glycosylation Quantitation of 50 Serum Glycoproteins Enhanced by Predictive Glycopeptidomics for Improved Disease Biomarker Discovery.Li Q, Kailemia MJ, Merleev AA, Xu G, Serie D, Danan LM, Haj FG, Maverakis E, Lebrilla CB Analytical chemistry, 2019 (91), 5433 - 5445 | | Submitted Externally | 30882205 | Published | |
| | | Submitted Externally | 30910807 | Published | |
| | | | 30957016 | Published | |
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| A New Animal Model of Insulin-Glucose Dynamics in the Intraperitoneal Space Enhances Closed-Loop Control Performance.Chakrabarty A, Gregory JM, Moore LM, Williams PE, Farmer B, Cherrington AD, Lord P, Shelton B, Cohen D, Zisser HC, Doyle FJ, Dassau E Journal of process control, 2019 (76), 62 - 73 | | Submitted Externally | 31178632 | Published | |
| Loss of Nuclear and Membrane Estrogen Receptor-a Differentially Impairs Insulin Secretion and Action in Male and Female Mice.Allard C, Morford JJ, Xu B, Salwen B, Xu W, Desmoulins L, Zsombok A, Kim JK, Levin ER, Mauvais-Jarvis F Diabetes, 2019 (68), 490 - 501 | | Submitted Externally | 30305367 | Published | |
| Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery.Albaugh VL, Banan B, Antoun J, Xiong Y, Guo Y, Ping J, Alikhan M, Clements BA, Abumrad NN, Flynn CR Gastroenterology, 2019 (156), 1041 - 1051.e4 | | Submitted Externally | 30445014 | Published | |
| Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic ß Cells for In Vitro and In Vivo Analysis.Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, Sévigny J, Powers AC Cell Metabolism, 2019 (29), 745 - 754.e4 | | Submitted Externally | 30449685 | Published | |
| | | Submitted Externally | 30782860 | Published | |
| Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic.Batiste SM, Blackwell DJ, Kim K, Kryshtal DO, Gomez-Hurtado N, Rebbeck RT, Cornea RL, Johnston JN, Knollmann BC Proceedings of the National Academy of Sciences of the United States of America, 2019 (116), 4810 - 4815 | | Submitted Externally | 30792355 | Published | |
| Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans.Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Péterfy M Obesity (Silver Spring, Md.), 2019 (27), 434 - 443 | | Submitted Externally | 30801985 | Published | |
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| Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion.Sedgeman LR, Beysen C, Ramirez Solano MA, Michell DL, Sheng Q, Zhao S, Turner S, Linton MF, Vickers KC Scientific reports, 2019 (9), 3803 | | Submitted Externally | 30846744 | Published | |
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| Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo.Batista TM, Garcia-Martin R, Cai W, Konishi M, O'Neill BT, Sakaguchi M, Kim JH, Jung DY, Kim JK, Kahn CR Cell reports, 2019 (26), 3429 - 3443.e3 | | Submitted Externally | 30893613 | Published | |
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| Examining How the MAFB Transcription Factor Affects Islet ß-Cell Function Postnatally.Cyphert HA, Walker EM, Hang Y, Dhawan S, Haliyur R, Bonatakis L, Avrahami D, Brissova M, Kaestner KH, Bhushan A, Powers AC, Stein R Diabetes, 2019 (68), 337 - 348 | | Submitted Externally | 30425060 | Published | |
| Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes.Jackson MA, Bedingfield SK, Yu F, Stokan ME, Miles RE, Curvino EJ, Hoogenboezem EN, Bonami RH, Patel SS, Kendall PL, Giorgio TD, Duvall CL Biomaterials, 2019 (192), 245 - 259 | | Submitted Externally | 30458360 | Published | |
| Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice.Tooke BP, Yu H, Adams JM, Jones GL, Sutton-Kennedy T, Mundada L, Qi NR, Low MJ, Chhabra KH Molecular metabolism, 2019 (20), 194 - 204 | | Submitted Externally | 30503832 | Published | |
| | | Submitted Externally | 30541071 | Published | |
| Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.Babaev VR, Ding L, Zhang Y, May JM, Ramsey SA, Vickers KC, Linton MF Arteriosclerosis, thrombosis, and vascular biology, 2019 (39), 156 - 169 | | Submitted Externally | 30567482 | Published | |
| | | Submitted Externally | 30576919 | Published | |
| Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability.Kilchrist KV, Dimobi SC, Jackson MA, Evans BC, Werfel TA, Dailing EA, Bedingfield SK, Kelly IB, Duvall CL ACS nano, 2019 (13), 1136 - 1152 | | Submitted Externally | 30629431 | Published | |
| New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications.Engelhardt BG, Savani U, Jung DK, Powers AC, Jagasia M, Chen H, Winnick JJ, Tamboli RA, Crowe JE, Abumrad NN Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019 | | Submitted Externally | 30738170 | Published | |
| Disabling the Gß?-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes.Zurawski Z, Thompson Gray AD, Brady LJ, Page B, Church E, Harris NA, Dohn MR, Yim YY, Hyde K, Mortlock DP, Jones CK, Winder DG, Alford S, Hamm HE Science signaling, 2019 (12) | | Submitted Externally | 30783011 | Published | |
| Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency.Jakkamsetti V, Marin-Valencia I, Ma Q, Good LB, Terrill T, Rajasekaran K, Pichumani K, Khemtong C, Hooshyar MA, Sundarrajan C, Patel MS, Bachoo RM, Malloy CR, Pascual JM Science translational medicine, 2019 (11) | | Submitted Externally | 30787166 | Published | |
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| Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.Edgerton DS, Scott M, Farmer B, Williams PE, Madsen P, Kjeldsen T, Brand CL, Fledelius C, Nishimura E, Cherrington AD JCI insight, 2019 (5) | | Submitted Externally | 30830873 | Published | |
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| Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM Nature medicine, 2019 (25), 141 - 151 | | Submitted Externally | 30420753 | Published | |
| | | Submitted Externally | 30470572 | Published | |
| a2A-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity In Vivo.Fetterly TL, Basu A, Nabit BP, Awad E, Williford KM, Centanni SW, Matthews RT, Silberman Y, Winder DG The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019 (39), 472 - 484 | | Submitted Externally | 30478032 | Published | |
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| Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity.Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G Developmental cell, 2019 (48), 49 - 63.e7 | | Submitted Externally | 30620902 | Published | |
| Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones.Herber CB, Krause WC, Wang L, Bayrer JR, Li A, Schmitz M, Fields A, Ford B, Zhang Z, Reid MS, Nomura DK, Nissenson RA, Correa SM, Ingraham HA Nature communications, 2019 (10), 163 | | Submitted Externally | 30635563 | Published | |
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| Genomic landscape of a metastatic malignant proliferating tricholemmal tumor and its response to PI3K inhibition.Gallant JN, Sewell A, Almodovar K, Wang Q, Dahlman KB, Abramson RG, Kapp ME, Brown BT, Boyd KL, Gilbert J, Cohen DN, Yarbrough WG, Zhao Z, Lovly CM NPJ precision oncology, 2019 (3), 5 | | Submitted Externally | 30793038 | Published | |
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| Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis.Wen HJ, Gao S, Wang Y, Ray M, Magnuson MA, Wright CVE, Di Magliano MP, Frankel TL, Crawford HC Cellular and molecular gastroenterology and hepatology, 2019 (8), 173 - 192 | | Submitted Externally | 31125624 | Published | |
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| | | Submitted Externally | 31751387 | Published | |
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| MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome.Vogel Ciernia A, Yasui DH, Pride MC, Durbin-Johnson B, Noronha AB, Chang A, Knotts TA, Rutkowsky JR, Ramsey JJ, Crawley JN, LaSalle JM Human molecular genetics, 2018 (27), 4077 - 4093 | | Submitted Externally | 30137367 | Published | |
| CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet.Zhu L, Luu T, Emfinger CH, Parks BA, Shi J, Trefts E, Zeng F, Kuklenyik Z, Harris RC, Wasserman DH, Fazio S, Stafford JM Diabetes, 2018 (67), 2494 - 2506 | | Submitted Externally | 30213825 | Published | |
| Hydroxypropyl-ß-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis.Mitrofanova A, Molina J, Varona Santos J, Guzman J, Morales XA, Ducasa GM, Bryn J, Sloan A, Volosenco I, Kim JJ, Ge M, Mallela SK, Kretzler M, Eddy S, Martini S, Wahl P, Pastori S, Mendez AJ, Burke GW, Merscher S, Fornoni A Kidney international, 2018 (94), 1151 - 1159 | | Submitted Externally | 30301568 | Published | |
| | | Submitted Externally | 30350640 | Published | |
| | | Submitted Externally | 30446513 | Published | |
| Beyond the H&E: Advanced Technologies for in situ Tissue Biomarker Imaging.Himmel LE, Hackett TA, Moore JL, Adams WR, Thomas G, Novitskaya T, Caprioli RM, Zijlstra A, Mahadevan-Jansen A, Boyd KL ILAR journal, 2018 (59), 51 - 65 | | Submitted Externally | 30462242 | Published | |
| Trauma-Induced Nanohydroxyapatite Deposition in Skeletal Muscle is Sufficient to Drive Heterotopic Ossification.Moore-Lotridge SN, Li Q, Gibson BHY, Martin JT, Hawley GD, Arnold TH, Saito M, Tannouri S, Schwartz HS, Gumina RJ, Cates JMM, Uitto J, Schoenecker JG Calcified tissue international, 2018 | | Submitted Externally | 30515544 | Published | |
| | | Submitted Externally | 30529515 | Published | |
| Protein kinase D mediates inflammatory responses of human placental macrophages to Group B Streptococcus.Sutton JA, Rogers LM, Dixon B, Kirk L, Doster R, Algood HM, Gaddy JA, Flaherty R, Manning SD, Aronoff DM American journal of reproductive immunology (New York, N.Y. : 1989), 2018, e13075 | | Submitted Externally | 30582878 | Published | |
| Diabetes-associated alterations in the cecal microbiome and metabolome are independent of diet or environment in the UC Davis Type 2 Diabetes Mellitus Rat model.Piccolo BD, Graham JL, Stanhope KL, Nookaew I, Mercer KE, Chintapalli SV, Wankhade UD, Shankar K, Havel PJ, Adams SH American journal of physiology. Endocrinology and metabolism, 2018 (315), E961 - E972 | | Submitted Externally | 30016149 | Published | |
| | | Submitted Externally | 30085125 | Published | |
| Reversible deficits in apical transporter trafficking associated with deficiency in diacylglycerol acyltransferase.Schlegel C, Lapierre LA, Weis VG, Williams JA, Kaji I, Pinzon-Guzman C, Prasad N, Boone B, Jones A, Correa H, Levy SE, Han X, Wang M, Thomsen K, Acra S, Goldenring JR Traffic (Copenhagen, Denmark), 2018 (19), 879 - 892 | | Submitted Externally | 30095213 | Published | |
| Absence of leptin signaling allows fat accretion in cystic fibrosis mice.Bederman IR, Pora G, O'Reilly M, Poleman J, Spoonhower K, Puchowicz M, Perez A, Erokwu BO, Rodriguez-Palacios A, Flask CA, Drumm ML American journal of physiology. Gastrointestinal and liver physiology, 2018 (315), G685 - G698 | | Submitted Externally | 30118352 | Published | |
| | | Submitted Externally | 30184329 | Published | |
| CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure.Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline RH, Kim JK, Czech MP The Journal of biological chemistry, 2018 (293), 17291 - 17305 | | Submitted Externally | 30190322 | Published | |
| Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids.Hill SJ, Decker B, Roberts EA, Horowitz NS, Muto MG, Worley MJ, Feltmate CM, Nucci MR, Swisher EM, Nguyen H, Yang C, Morizane R, Kochupurakkal BS, Do KT, Konstantinopoulos PA, Liu JF, Bonventre JV, Matulonis UA, Shapiro GI, Berkowitz RS, Crum CP, D'Andrea AD Cancer discovery, 2018 (8), 1404 - 1421 | | Submitted Externally | 30213835 | Published | |
| Glutamate-Glutamine Transfer and Chronic Stress-Induced Sex Differences in Cocaine Responses.Shimamoto A, Rappeneau V, Munjal H, Farris T, Davis C, Wilson A, Edwards M, Moore C, Reynolds C, Meshul CK Neuroscience, 2018 (391), 104 - 119 | | Submitted Externally | 30240589 | Published | |
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| BDNF mimetic alleviates body weight gain in obese mice by enhancing mitochondrial biogenesis in skeletal muscle.Wood J, Tse MCL, Yang X, Brobst D, Liu Z, Pang BPS, Chan WS, Zaw AM, Chow BKC, Ye K, Lee CW, Chan CB Metabolism: clinical and experimental, 2018 (87), 113 - 122 | | Submitted Externally | 29935237 | Published | |
| Settable polymer/ceramic composite bone grafts stabilize weight-bearing tibial plateau slot defects and integrate with host bone in an ovine model.Lu S, McGough MAP, Shiels SM, Zienkiewicz KJ, Merkel AR, Vanderburgh JP, Nyman JS, Sterling JA, Tennent DJ, Wenke JC, Guelcher SA Biomaterials, 2018 (179), 29 - 45 | | Submitted Externally | 29960822 | Published | |
| | | Submitted Externally | 30002132 | Published | |
| Decidual stromal cell-derived PGE2 regulates macrophage responses to microbial threat.Rogers LM, Anders AP, Doster RS, Gill EA, Gnecco JS, Holley JM, Randis TM, Ratner AJ, Gaddy JA, Osteen K, Aronoff DM American journal of reproductive immunology (New York, N.Y. : 1989), 2018 (80), e13032 | | Submitted Externally | 30084522 | Published | |
| Dorsal BNST a2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors.Harris NA, Isaac AT, Günther A, Merkel K, Melchior J, Xu M, Eguakun E, Perez R, Nabit BP, Flavin S, Gilsbach R, Shonesy B, Hein L, Abel T, Baumann A, Matthews R, Centanni SW, Winder DG The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018 (38), 8922 - 8942 | | Submitted Externally | 30150361 | Published | |
| Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study.Salisbury-Ruf CT, Bertram CC, Vergeade A, Lark DS, Shi Q, Heberling ML, Fortune NL, Okoye GD, Jerome WG, Wells QS, Fessel J, Moslehi J, Chen H, Roberts LJ, Boutaud O, Gamazon ER, Zinkel SS eLife, 2018 (7) | | Submitted Externally | 30281024 | Published | |
| LNK deficiency promotes acute aortic dissection and rupture.Laroumanie F, Korneva A, Bersi MR, Alexander MR, Xiao L, Zhong X, Van Beusecum JP, Chen Y, Saleh MA, McMaster WG, Gavulic KA, Dale BL, Zhao S, Guo Y, Shyr Y, Perrien DS, Cox NJ, Curci JA, Humphrey JD, Madhur MS JCI insight, 2018 (3) | | Submitted Externally | 30333305 | Published | |
| p73 Is Required for Ovarian Follicle Development and Regulates a Gene Network Involved in Cell-to-Cell Adhesion.Santos Guasch GL, Beeler JS, Marshall CB, Shaver TM, Sheng Q, Johnson KN, Boyd KL, Venters BJ, Cook RS, Pietenpol JA iScience, 2018 (8), 236 - 249 | | Submitted Externally | 30340069 | Published | |
| | | Submitted Externally | 30355312 | Published | |
| Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism.Tassi E, Garman KA, Schmidt MO, Ma X, Kabbara KW, Uren A, Tomita Y, Goetz R, Mohammadi M, Wilcox CS, Riegel AT, Carlstrom M, Wellstein A Scientific reports, 2018 (8), 15973 | | Submitted Externally | 30374109 | Published | |
| BVES is required for maintenance of colonic epithelial integrity in experimental colitis by modifying intestinal permeability.Choksi YA, Reddy VK, Singh K, Barrett CW, Short SP, Parang B, Keating CE, Thompson JJ, Verriere TG, Brown RE, Piazuelo MB, Bader DM, Washington MK, Mittal MK, Brand T, Gobert AP, Coburn LA, Wilson KT, Williams CS Mucosal immunology, 2018 (11), 1363 - 1374 | | Submitted Externally | 29907869 | Published | |
| | | Submitted Externally | 29917234 | Published | |
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| Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.Hunter RW, Hughey CC, Lantier L, Sundelin EI, Peggie M, Zeqiraj E, Sicheri F, Jessen N, Wasserman DH, Sakamoto K Nature medicine, 2018 (24), 1395 - 1406 | | Submitted Externally | 30150719 | Published | |
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| Apolipoprotein A-IV binds aIIbß3 integrin and inhibits thrombosis.Xu XR, Wang Y, Adili R, Ju L, Spring CM, Jin JW, Yang H, Neves MAD, Chen P, Yang Y, Lei X, Chen Y, Gallant RC, Xu M, Zhang H, Song J, Ke P, Zhang D, Carrim N, Yu SY, Zhu G, She YM, Cyr T, Fu W, Liu G, Connelly PW, Rand ML, Adeli K, Freedman J, Lee JE, Tso P, Marchese P, Davidson WS, Jackson SP, Zhu C, Ruggeri ZM, Ni H Nature communications, 2018 (9), 3608 | | Submitted Externally | 30190457 | Published | |
| Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology.Zhang C, Seo J, Murakami K, Salem ESB, Bernhard E, Borra VJ, Choi K, Yuan CL, Chan CC, Chen X, Huang T, Weirauch MT, Divanovic S, Qi NR, Thomas HE, Mercer CA, Siomi H, Nakamura T Nature communications, 2018 (9), 3658 | | Submitted Externally | 30201950 | Published | |
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| Palatable Food Affects HPA Axis Responsivity and Forebrain Neurocircuitry in an Estrous Cycle-specific Manner in Female Rats.Egan AE, Thompson AMK, Buesing D, Fourman SM, Packard AEB, Terefe T, Li D, Wang X, Song S, Solomon MB, Ulrich-Lai YM Neuroscience, 2018 (384), 224 - 240 | | Submitted Externally | 29852242 | Published | |
| Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance.Rupp AC, Allison MB, Jones JC, Patterson CM, Faber CL, Bozadjieva N, Heisler LK, Seeley RJ, Olson DP, Myers MG Molecular metabolism, 2018 (14), 130 - 138 | | Submitted Externally | 29914853 | Published | |
| | | Submitted Externally | 29950508 | Published | |
| | | Submitted Externally | 30051127 | Published | |
| Lacteal junction zippering protects against diet-induced obesity.Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong GH, Simons M, Tso P, Fernández-Hernando C, Shulman GI, Sessa WC, Eichmann A Science (New York, N.Y.), 2018 (361), 599 - 603 | | Submitted Externally | 30093598 | Published | |
| | | Submitted Externally | 30143599 | Published | |
| Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice.Mi DJ, Dixit S, Warner TA, Kennard JA, Scharf DA, Kessler ES, Moore LM, Consoli DC, Bown CW, Eugene AJ, Kang JQ, Harrison FE Neurobiology of aging, 2018 (71), 241 - 254 | | Submitted Externally | 30172223 | Published | |
| Single Quantum Dot Tracking Illuminates Neuroscience at the Nanoscale.Kovtun O, Tomlinson ID, Bailey DM, Thal LB, Ross EJ, Harris L, Frankland MP, Ferguson RS, Glaser Z, Greer J, Rosenthal SJ Chemical physics letters, 2018 (706), 741 - 752 | | Submitted Externally | 30270931 | Published | |
| | | Submitted Externally | 29666062 | Published | |
| A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL.Cooke AL, Morris J, Melchior JT, Street SE, Jerome WG, Huang R, Herr AB, Smith LE, Segrest JP, Remaley AT, Shah AS, Thompson TB, Davidson WS Journal of lipid research, 2018 (59), 1244 - 1255 | | Submitted Externally | 29773713 | Published | |
| | | Submitted Externally | 29891549 | Published | |
| | | Submitted Externally | 29973630 | Published | |
| The impact of aging, calorie restriction and dietary fat on mitochondrial ultrastructure, dynamics and autophagy markers in mouse skeletal muscle.Gutiérrez-Casado E, Khraiwesh H, López-Domínguez JA, Montero-Guisado J, López-Lluch G, Navas P, de Cabo R, Ramsey JJ, González-Reyes JA, Villalba JM The journals of gerontology. Series A, Biological sciences and medical sciences, 2018 | | Submitted Externally | 30010806 | Published | |
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| Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action.Allison MB, Pan W, MacKenzie A, Patterson C, Shah K, Barnes T, Cheng W, Rupp A, Olson DP, Myers MG Diabetes, 2018 (67), 1093 - 1104 | | Submitted Externally | 29535089 | Published | |
| Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts.Moore MC, Kelley DE, Camacho RC, Zafian P, Ye T, Lin S, Kaarsholm NC, Nargund R, Kelly TM, Van Heek M, Previs SF, Moyes C, Smith MS, Farmer B, Williams P, Cherrington AD Diabetes, 2018 (67), 1173 - 1181 | | Submitted Externally | 29540491 | Published | |
| | | | 29659785 | Published | |
| The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism.Fensterheim BA, Young JD, Luan L, Kleinbard RR, Stothers CL, Patil NK, McAtee-Pereira AG, Guo Y, Trenary I, Hernandez A, Fults JB, Williams DL, Sherwood ER, Bohannon JK Journal of immunology (Baltimore, Md. : 1950), 2018 (200), 3777 - 3789 | | Submitted Externally | 29686054 | Published | |
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| Autophagy Differentially Regulates Insulin Production and Insulin Sensitivity.Yamamoto S, Kuramoto K, Wang N, Situ X, Priyadarshini M, Zhang W, Cordoba-Chacon J, Layden BT, He C Cell reports, 2018 (23), 3286 - 3299 | | Submitted Externally | 29898399 | Published | |
| | | Submitted Externally | 29908041 | Published | |
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| Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass.Purnell JQ, Johnson GS, Wahed AS, Dalla Man C, Piccinini F, Cobelli C, Prigeon RL, Goodpaster BH, Kelley DE, Staten MA, Foster-Schubert KE, Cummings DE, Flum DR, Courcoulas AP, Havel PJ, Wolfe BM Diabetologia, 2018 (61), 1142 - 1154 | | Submitted Externally | 29428999 | Published | |
| Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.Flores DJ, Duong T, Brandenberger LO, Mitra A, Shirali A, Johnson JC, Springer D, Noguchi A, Yu ZX, Ebert SN, Ludwig A, Knollmann BC, Levin MD, Pfeifer K Human molecular genetics, 2018 (27), 1533 - 1544 | | Submitted Externally | 29452352 | Published | |
| | | Submitted Externally | 29511026 | Published | |
| Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection.Brown JJ, Short SP, Stencel-Baerenwald J, Urbanek K, Pruijssers AJ, McAllister N, Ikizler M, Taylor G, Aravamudhan P, Khomandiak S, Jabri B, Williams CS, Dermody TS Journal of virology, 2018 (92) | | Submitted Externally | 29514905 | Published | |
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| Synaptotagmin 4 Regulates Pancreatic ß Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G Developmental cell, 2018 (45), 347 - 361.e5 | | Submitted Externally | 29656931 | Published | |
| | | Submitted Externally | 29686091 | Published | |
| A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA Cell Metabolism, 2018 (27), 1156 | | Submitted Externally | 29719228 | Published | |
| Assessment of renal fibrosis in murine diabetic nephropathy using quantitative magnetization transfer MRI.Wang F, Katagiri D, Li K, Takahashi K, Wang S, Nagasaka S, Li H, Quarles CC, Zhang MZ, Shimizu A, Gore JC, Harris RC, Takahashi T Magnetic Resonance in Medicine, 2018 | | Submitted Externally | 29845659 | Published | |
| Dioxin-like PCB 126 Increases Systemic Inflammation and Accelerates Atherosclerosis in Lean LDL Receptor-Deficient Mice.Petriello MC, Brandon JA, Hoffman J, Wang C, Tripathi H, Abdel-Latif A, Ye X, Li X, Yang L, Lee E, Soman S, Barney J, Wahlang B, Hennig B, Morris AJ Toxicological sciences : an official journal of the Society of Toxicology, 2018 (162), 548 - 558 | | Submitted Externally | 29216392 | Published | |
| Endoplasmic reticulum chaperone GRP78 regulates macrophage function and insulin resistance in diet-induced obesity.Kim JH, Lee E, Friedline RH, Suk S, Jung DY, Dagdeviren S, Hu X, Inashima K, Noh HL, Kwon JY, Nambu A, Huh JR, Han MS, Davis RJ, Lee AS, Lee KW, Kim JK FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018 (32), 2292 - 2304 | | Submitted Externally | 29242277 | Published | |
| AMPK in skeletal muscle function and metabolism.Kjøbsted R, Hingst JR, Fentz J, Foretz M, Sanz MN, Pehmøller C, Shum M, Marette A, Mounier R, Treebak JT, Wojtaszewski JFP, Viollet B, Lantier L FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018 (32), 1741 - 1777 | | Submitted Externally | 29242278 | Published | |
| Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity.Owino S, Sánchez-Bretaño A, Tchio C, Cecon E, Karamitri A, Dam J, Jockers R, Piccione G, Noh HL, Kim T, Kim JK, Baba K, Tosini G Journal of pineal research, 2018 (64) | | Submitted Externally | 29247541 | Published | |
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| Essential Role for Hypothalamic Calcitonin Receptor?Expressing Neurons in the Control of Food Intake by Leptin.Pan W, Adams JM, Allison MB, Patterson C, Flak JN, Jones J, Strohbehn G, Trevaskis J, Rhodes CJ, Olson DP, Myers MG Endocrinology, 2018 (159), 1860 - 1872 | | Submitted Externally | 29522093 | Published | |
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| Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria.Majtan T, Jones W, Krijt J, Park I, Kruger WD, Kožich V, Bassnett S, Bublil EM, Kraus JP Molecular therapy : the journal of the American Society of Gene Therapy, 2018 (26), 834 - 844 | | Submitted Externally | 29398487 | Published | |
| | | Submitted Externally | 29402588 | Published | |
| Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.Kim GH, Shi G, Somlo DR, Haataja L, Song S, Long Q, Nillni EA, Low MJ, Arvan P, Myers MG, Qi L The Journal of clinical investigation, 2018 (128), 1125 - 1140 | | Submitted Externally | 29457782 | Published | |
| Myeloid-Specific Deletion of Zfp36 Protects Against Insulin Resistance and Fatty Liver in Diet-Induced Obese Mice.Caracciolo V, Young J, Gonzales D, Ni Y, Flowers SJ, Summer R, Waldman SA, Kim JK, Jung DY, Noh HL, Kim T, Blackshear PJ, O'Connell D, Bauer RC, Kallen CB American journal of physiology. Endocrinology and metabolism, 2018 | | Submitted Externally | 29509432 | Published | |
| Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity.Huang LH, Melton EM, Li H, Sohn P, Jung D, Tsai CY, Ma T, Sano H, Ha H, Friedline RH, Kim JK, Usherwood E, Chang CC, Chang TY American journal of physiology. Endocrinology and metabolism, 2018 | | Submitted Externally | 29533741 | Published | |
| Association of Pathological Fibrosis With Renal Survival Using Deep Neural Networks.Kolachalama VB, Singh P, Lin CQ, Mun D, Belghasem ME, Henderson JM, Francis JM, Salant DJ, Chitalia VC Kidney international reports, 2018 (3), 464 - 475 | | Submitted Externally | 29725651 | Published | |
| | | Submitted Externally | 28982731 | Published | |
| | | Submitted Externally | 29024407 | Published | |
| 17a-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior.Steyn FJ, Ngo ST, Chen VP, Bailey-Downs LC, Xie TY, Ghadami M, Brimijoin S, Freeman WM, Rubinstein M, Low MJ, Stout MB Aging cell, 2018 (17) | | Submitted Externally | 29168299 | Published | |
| Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling.Corbit KC, Camporez JPG, Edmunds LR, Tran JL, Vera NB, Erion DM, Deo RC, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ Diabetes, 2018 (67), 208 - 221 | | Submitted Externally | 29203511 | Published | |
| | | Submitted Externally | 29263093 | Published | |
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| Adropin: An endocrine link between the biological clock and cholesterol homeostasis.Ghoshal S, Stevens JR, Billon C, Girardet C, Sitaula S, Leon AS, Rao DC, Skinner JS, Rankinen T, Bouchard C, Nuñez MV, Stanhope KL, Howatt DA, Daugherty A, Zhang J, Schuelke M, Weiss EP, Coffey AR, Bennett BJ, Sethupathy P, Burris TP, Havel PJ, Butler AA Molecular metabolism, 2018 (8), 51 - 64 | | Submitted Externally | 29331507 | Published | |
| Hepatic Gi signaling regulates whole-body glucose homeostasis.Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, Finkel T, McGuinness OP, Wess J The Journal of clinical investigation, 2018 (128), 746 - 759 | | Submitted Externally | 29337301 | Published | |
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| | | Submitted Externally | 29474500 | Published | |
| Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice.Zhang K, Kim H, Fu Z, Qiu Y, Yang Z, Wang J, Zhang D, Tong X, Yin L, Li J, Wu J, Qi NR, Houten SM, Zhang R Gastroenterology, 2018 (154), 224 - 237 | | Submitted Externally | 28923496 | Published | |
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| Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Rozman J, Rathkolb B, Oestereicher MA, Schütt C, Ravindranath AC, Leuchtenberger S, Sharma S, Kistler M, Willershäuser M, Brommage R, Meehan TF, Mason J, Haselimashhadi H, Hough T, Mallon AM, Wells S, Santos L, Lelliott CJ, White JK, Sorg T, Champy MF, Bower LR, Reynolds CL, Flenniken AM, Murray SA, Nutter LMJ, Svenson KL, West D, Tocchini-Valentini GP, Beaudet AL, Bosch F, Braun RB, Dobbie MS, Gao X, Herault Y, Moshiri A, Moore BA, Kent Lloyd KC, McKerlie C, Masuya H, Tanaka N, Flicek P, Parkin Nature communications, 2018 (9), 288 | | Submitted Externally | 29348434 | Published | |
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| | | Submitted Externally | 29290798 | Published | |
| Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet.Rutkowsky JM, Lee LL, Puchowicz M, Golub MS, Befroy DE, Wilson DW, Anderson S, Cline G, Bini J, Borkowski K, Knotts TA, Rutledge JC, PLoS ONE, 2018 (13), e0191909 | | Submitted Externally | 29444171 | Published | |
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| Unexpected timely fracture union in matrix metalloproteinase 9 deficient mice.Yuasa M, Saito M, Molina C, Moore-Lotridge SN, Benvenuti MA, Mignemi NA, Okawa A, Yoshii T, Schwartz HS, Nyman JS, Schoenecker JG PLoS ONE, 2018 (13), e0198088 | | Submitted Externally | 29851987 | Published | |
| | | Submitted Externally | 29904577 | Published | |
| | | Submitted Externally | 30533032 | Published | |
| Transgenic mice with ectopic expression of constitutively active TLR4 in adipose tissues do not show impaired insulin sensitivity.Ono-Moore KD, Zhao L, Huang S, Kim J, Rutkowsky JM, Snodgrass RG, Schneider DA, Quon MJ, Graham JL, Havel PJ, Hwang DH Immunity, inflammation and disease, 2017 (5), 526 - 540 | | Submitted Externally | 28776958 | Published | |
| Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.Kobayashi H, Liu J, Urrutia AA, Burmakin M, Ishii K, Rajan M, Davidoff O, Saifudeen Z, Haase VH Kidney international, 2017 (92), 1370 - 1383 | | Submitted Externally | 28847650 | Published | |
| Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice.Russo L, Muturi HT, Ghadieh HE, Ghanem SS, Bowman TA, Noh HL, Dagdeviren S, Dogbey GY, Kim JK, Heinrich G, Najjar SM Diabetologia, 2017 (60), 2463 - 2474 | | Submitted Externally | 28913658 | Published | |
| Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice.Argmann CA, Violante S, Dodatko T, Amaro MP, Hagen J, Gillespie VL, Buettner C, Schadt EE, Houten SM Biochimica et biophysica acta. Molecular basis of disease, 2017 (1863), 3277 - 3285 | | Submitted Externally | 28962896 | Published | |
| | | Submitted Externally | 29037594 | Published | |
| | | Submitted Externally | 29037812 | Published | |
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| IRF3 and type I interferons fuel a fatal response to myocardial infarction.King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R Nature medicine, 2017 (23), 1481 - 1487 | | Submitted Externally | 29106401 | Published | |
| | | Submitted Externally | 29208682 | Published | |
| Alpha2delta-1 in SF1+ Neurons of the Ventromedial Hypothalamus Is an Essential Regulator of Glucose and Lipid Homeostasis.Felsted JA, Chien CH, Wang D, Panessiti M, Ameroso D, Greenberg A, Feng G, Kong D, Rios M Cell reports, 2017 (21), 2737 - 2747 | | Submitted Externally | 29212022 | Published | |
| | | Submitted Externally | 29216341 | Published | |
| Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes.Kim SP, Frey JL, Li Z, Kushwaha P, Zoch ML, Tomlinson RE, Da H, Aja S, Noh HL, Kim JK, Hussain MA, Thorek DLJ, Wolfgang MJ, Riddle RC Proceedings of the National Academy of Sciences of the United States of America, 2017 (114), E11238 - E11247 | | Submitted Externally | 29229807 | Published | |
| | | Submitted Externally | 29243276 | Published | |
| Defining a Novel Role for the Pdx1 Transcription Factor in Islet ß-Cell Maturation and Proliferation During Weaning.Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R Diabetes, 2017 (66), 2830 - 2839 | | Submitted Externally | 28705881 | Published | |
| | | Submitted Externally | 28754792 | Published | |
| Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG Biochimica et biophysica acta, 2017 (1861), 2758 - 2765 | | Submitted Externally | 28757338 | Published | |
| Porcine Ischemic Wound-Healing Model for Preclinical Testing of Degradable Biomaterials.Patil P, Martin JR, Sarett SM, Pollins AC, Cardwell NL, Davidson JM, Guelcher SA, Nanney LB, Duvall CL Tissue engineering. Part C, Methods, 2017 (23), 754 - 762 | | Submitted Externally | 28762881 | Published | |
| | | Submitted Externally | 28768657 | Published | |
| Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase-Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance.Watt NT, Gage MC, Patel PA, Viswambharan H, Sukumar P, Galloway S, Yuldasheva NY, Imrie H, Walker AMN, Griffin KJ, Makava N, Skromna A, Bridge K, Beech DJ, Schurmans S, Wheatcroft SB, Kearney MT, Cubbon RM Diabetes, 2017 (66), 2808 - 2821 | | Submitted Externally | 28830894 | Published | |
| A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams AL, Bonàs-Guarch S, Hartl C, Ripke S, Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Diabetes, 2017 (66), 2903 - 2914 | | Submitted Externally | 28838971 | Published | |
| | | Submitted Externally | 28847566 | Published | |
| | | Submitted Externally | 28870520 | Published | |
| | | Submitted Externally | 28904206 | Published | |
| | | Submitted Externally | 28922564 | Published | |
| | | Submitted Externally | 28931596 | Published | |
| | | Submitted Externally | 28987240 | Published | |
| The Gain-of-Function Integrin ß3 Pro33 Variant Alters the Serotonin System in the Mouse Brain.Dohn MR, Kooker CG, Bastarache L, Jessen T, Rinaldi C, Varney S, Mazalouskas MD, Pan H, Oliver KH, Velez Edwards DR, Sutcliffe JS, Denny JC, Carneiro AMD The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017 (37), 11271 - 11284 | | Submitted Externally | 29038237 | Published | |
| The liver.Trefts E, Gannon M, Wasserman DH Current biology : CB, 2017 (27), R1147 - R1151 | | Submitted Externally | 29112863 | Published | |
| Gingerenone A, a polyphenol present in ginger, suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice.Suk S, Kwon GT, Lee E, Jang WJ, Yang H, Kim JH, Thimmegowda NR, Chung MY, Kwon JY, Yang S, Kim JK, Park JHY, Lee KW Molecular nutrition & food research, 2017 (61) | | Submitted Externally | 28556482 | Published | |
| | | Submitted Externally | 28573762 | Published | |
| Human germline hedgehog pathway mutations predispose to fatty liver.Guillen-Sacoto MJ, Martinez AF, Abe Y, Kruszka P, Weiss K, Everson JL, Bataller R, Kleiner DE, Ward JM, Sulik KK, Lipinski RJ, Solomon BD, Muenke M Journal of hepatology, 2017 (67), 809 - 817 | | Submitted Externally | 28645738 | Published | |
| Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity.Gao Y, Layritz C, Legutko B, Eichmann TO, Laperrousaz E, Moullé VS, Cruciani-Guglielmacci C, Magnan C, Luquet S, Woods SC, Eckel RH, Yi CX, Garcia-Caceres C, Tschöp MH Diabetes, 2017 (66), 2555 - 2563 | | | 28710138 | Published | |
| Regulation of Macrophage Apoptosis and Atherosclerosis by Lipid-Induced PKCd Isoform Activation.Li Q, Park K, Xia Y, Matsumoto M, Qi W, Fu J, Yokomizo H, Khamaisi M, Wang X, Rask-Madsen C, King GL Circulation research, 2017 (121), 1153 - 1167 | | Submitted Externally | 28855204 | Published | |
| | | Submitted Externally | 28916724 | Published | |
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| | | | 28890107 | Published | |
| | | Submitted Externally | 27923718 | Published | |
| | | Submitted Externally | 28449850 | Published | |
| Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice.Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ Cellular and molecular gastroenterology and hepatology, 2017 (4), 223 - 236 | | Submitted Externally | 28649594 | Published | |
| Identification of Proteomic Features To Distinguish Benign Pulmonary Nodules from Lung Adenocarcinoma.Codreanu SG, Hoeksema MD, Slebos RJC, Zimmerman LJ, Rahman SMJ, Li M, Chen SC, Chen H, Eisenberg R, Liebler DC, Massion PP Journal of proteome research, 2017 (16), 3266 - 3276 | | Submitted Externally | 28731711 | Published | |
| The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism.Bermingham DP, Hardaway JA, Refai O, Marks CR, Snider SL, Sturgeon SM, Spencer WC, Colbran RJ, Miller DM, Blakely RD The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017 (37), 9288 - 9304 | | Submitted Externally | 28842414 | Published | |
| A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA Cell Metabolism, 2017 (26), 539 - 546.e5 | | Submitted Externally | 28877457 | Published | |
| Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.Hwangbo C, Wu J, Papangeli I, Adachi T, Sharma B, Park S, Zhao L, Ju H, Go GW, Cui G, Inayathullah M, Job JK, Rajadas J, Kwei SL, Li MO, Morrison AR, Quertermous T, Mani A, Red-Horse K, Chun HJ Science translational medicine, 2017 (9) | | Submitted Externally | 28904225 | Published | |
| | | Submitted Externally | 28910603 | Published | |
| Hypothalamic Glucose Transport in Humans During Experimentally Induced Hypoglycemia-Associated Autonomic Failure.Seaquist ER, Moheet A, Kumar A, Deelchand DK, Terpstra M, Kubisiak K, Eberly LE, Henry PG, Joers JM, Öz G The Journal of clinical endocrinology and metabolism, 2017 (102), 3571 - 3580 | | Submitted Externally | 28911152 | Published | |
| | | Submitted Externally | 28928238 | Published | |
| | | Submitted Externally | 28930674 | Published | |
| Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy.Litt MJ, Okoye GD, Lark D, Cakir I, Moore C, Barber MC, Atkinson J, Fessel J, Moslehi J, Cone RD eLife, 2017 (6) | | Submitted Externally | 28829041 | Published | |
| Deletion of ghrelin prevents aging-associated obesity and muscle dysfunction without affecting longevity.Guillory B, Chen JA, Patel S, Luo J, Splenser A, Mody A, Ding M, Baghaie S, Anderson B, Iankova B, Halder T, Hernandez Y, Garcia JM Aging cell, 2017 (16), 859 - 869 | | Submitted Externally | 28585250 | Published | |
| A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.Rocchi A, Yamamoto S, Ting T, Fan Y, Sadleir K, Wang Y, Zhang W, Huang S, Levine B, Vassar R, He C PLoS genetics, 2017 (13), e1006962 | | Submitted Externally | 28806762 | Published | |
| | | Submitted Externally | 28806851 | Published | |
| | | Submitted Externally | 28726069 | Published | |
| EGFR-mediated macrophage activation promotes colitis-associated tumorigenesis.Hardbower DM, Coburn LA, Asim M, Singh K, Sierra JC, Barry DP, Gobert AP, Piazuelo MB, Washington MK, Wilson KT Oncogene, 2017 (36), 3807 - 3819 | | Submitted Externally | 28263971 | Published | |
| Tumor Necrosis Factor-a Promotes Phosphoinositide 3-Kinase Enhancer A and AMP-Activated Protein Kinase Interaction to Suppress Lipid Oxidation in Skeletal Muscle.Tse MCL, Herlea-Pana O, Brobst D, Yang X, Wood J, Hu X, Liu Z, Lee CW, Zaw AM, Chow BKC, Ye K, Chan CB Diabetes, 2017 (66), 1858 - 1870 | | Submitted Externally | 28404596 | Published | |
| Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis.Ehrhardt N, Doche ME, Chen S, Mao HZ, Walsh MT, Bedoya C, Guindi M, Xiong W, Ignatius Irudayam J, Iqbal J, Fuchs S, French SW, Mahmood Hussain M, Arditi M, Arumugaswami V, Péterfy M Human molecular genetics, 2017 (26), 2719 - 2731 | | Submitted Externally | 28449094 | Published | |
| Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury.Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Fatima H, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG The FEBS journal, 2017 (284), 1970 - 1986 | | Submitted Externally | 28485854 | Published | |
| Tunable Surface Repellency Maintains Stemness and Redox Capacity of Human Mesenchymal Stem Cells.Balikov DA, Crowder SW, Boire TC, Lee JB, Gupta MK, Fenix AM, Lewis HN, Ambrose CM, Short PA, Kim CS, Burnette DT, Reilly MA, Murthy NS, Kang ML, Kim WS, Sung HJ ACS applied materials & interfaces, 2017 (9), 22994 - 23006 | | Submitted Externally | 28621931 | Published | |
| | | | 28750413 | Published | |
| Theranostic Gold Nanoantennas for Simultaneous Multiplexed Raman Imaging of Immunomarkers and Photothermal Therapy.Webb JA, Ou YC, Faley S, Paul EP, Hittinger JP, Cutright CC, Lin EC, Bellan LM, Bardhan R ACS omega, 2017 (2), 3583 - 3594 | | Submitted Externally | 28782050 | Published | |
| | | Submitted Externally | 27636893 | Published | |
| Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans.Gangadhariah MH, Dieckmann BW, Lantier L, Kang L, Wasserman DH, Chiusa M, Caskey CF, Dickerson J, Luo P, Gamboa JL, Capdevila JH, Imig JD, Yu C, Pozzi A, Luther JM Diabetologia, 2017 (60), 1066 - 1075 | | Submitted Externally | 28352940 | Published | |
| | | Submitted Externally | 28381495 | Published | |
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| Correcting Postprandial Hyperglycemia in Zucker Diabetic Fatty Rats With an SGLT2 Inhibitor Restores Glucose Effectiveness in the Liver and Reduces Insulin Resistance in Skeletal Muscle.O'Brien TP, Jenkins EC, Estes SK, Castaneda AV, Ueta K, Farmer TD, Puglisi AE, Swift LL, Printz RL, Shiota M Diabetes, 2017 (66), 1172 - 1184 | | Submitted Externally | 28246292 | Published | |
| | | Submitted Externally | 28334953 | Published | |
| | | Submitted Externally | 28412351 | Published | |
| High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schroder A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Müller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J The Journal of clinical investigation, 2017 (127), 1944 - 1959 | | Submitted Externally | 28414295 | Published | |
| Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons.Cady G, Landeryou T, Garratt M, Kopchick JJ, Qi N, Garcia-Galiano D, Elias CF, Myers MG, Miller RA, Sandoval DA, Sadagurski M Molecular metabolism, 2017 (6), 393 - 405 | | Submitted Externally | 28462074 | Published | |
| | | Submitted Externally | 28467354 | Published | |
| Identification of a High-Affinity Pyruvate Receptor in Escherichia coli.Behr S, Kristoficova I, Witting M, Breland EJ, Eberly AR, Sachs C, Schmitt-Kopplin P, Hadjifrangiskou M, Jung K Scientific reports, 2017 (7), 1388 | | Submitted Externally | 28469239 | Published | |
| | | Submitted Externally | 27277698 | Published | |
| Role of cardiotrophin-1 in the regulation of metabolic circadian rhythms and adipose core clock genes in mice and characterization of 24-h circulating CT-1 profiles in normal-weight and overweight/obese subjects.López-Yoldi M, Stanhope KL, Garaulet M, Chen XG, Marcos-Gómez B, Carrasco-Benso MP, Santa Maria EM, Escoté X, Lee V, Nunez MV, Medici V, Martínez-Ansó E, Sáinz N, Huerta AE, Laiglesia LM, Prieto J, Martínez JA, Bustos M, Havel PJ, Moreno-Aliaga MJ FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017 (31), 1639 - 1649 | | Submitted Externally | 28096235 | Published | |
| | | Submitted Externally | 28096260 | Published | |
| Effects of G6pc2 deletion on body weight and cholesterol in mice.Boortz KA, Syring KE, Pound LD, Mo H, Bastarache L, Oeser JK, McGuinness OP, Denny JC, O'Brien RM Journal of molecular endocrinology, 2017 (58), 127 - 139 | | Submitted Externally | 28122818 | Published | |
| | | Submitted Externally | 28236654 | Published | |
| Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.Bouziat R, Hinterleitner R, Brown JJ, Stencel-Baerenwald JE, Ikizler M, Mayassi T, Meisel M, Kim SM, Discepolo V, Pruijssers AJ, Ernest JD, Iskarpatyoti JA, Costes LM, Lawrence I, Palanski BA, Varma M, Zurenski MA, Khomandiak S, McAllister N, Aravamudhan P, Boehme KW, Hu F, Samsom JN, Reinecker HC, Kupfer SS, Guandalini S, Semrad CE, Abadie V, Khosla C, Barreiro LB, Xavier RJ, Ng A, Dermody TS, Jabri B Science (New York, N.Y.), 2017 (356), 44 - 50 | | Submitted Externally | 28386004 | Published | |
| Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues.Fidler AL, Darris CE, Chetyrkin SV, Pedchenko VK, Boudko SP, Brown KL, Gray Jerome W, Hudson JK, Rokas A, Hudson BG eLife, 2017 (6) | | Submitted Externally | 28418331 | Published | |
| | | Submitted Externally | 27986588 | Published | |
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| Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibility.LePage DP, Metcalf JA, Bordenstein SR, On J, Perlmutter JI, Shropshire JD, Layton EM, Funkhouser-Jones LJ, Beckmann JF, Bordenstein SR Nature, 2017 (543), 243 - 247 | | Submitted Externally | 28241146 | Published | |
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| Soluble epoxide hydrolase pharmacological inhibition decreases alveolar bone loss by modulating host inflammatory response, RANK-related signaling, ER stress and apoptosis.Trindade da Silva CA, Bettaieb A, Napimoga MH, Lee KS, Inceoglu B, Ueira-Vieira C, Bruun D, Goswami SK, Haj FG, Hammock BD The Journal of pharmacology and experimental therapeutics, 2017 | | Submitted Externally | 28356494 | Published | |
| Adipocyte JAK2 mediated growth hormone-induced hepatic insulin resistanceCorbit KC, Camporez JP, Tran JL, Wilson CG, Lowe DA, Nordstrom SM, Ganeshan K, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ JCI insight, 2017 (2(3)) | | | 28194444 | In press | |
| A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.Stephenson JR, Wang X, Perfitt TL, Parrish WP, Shonesy BC, Marks CR, Mortlock DP, Nakagawa T, Sutcliffe JS, Colbran RJ The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017 (37), 2216 - 2233 | | Submitted Externally | 28130356 | Published | |
| | | Submitted Externally | 27881673 | Published | |
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| MicroRNA-155 Deficiency Leads to Decreased Atherosclerosis, Increased White Adipose Tissue Obesity, and Non-alcoholic Fatty Liver Disease: A NOVEL MOUSE MODEL OF OBESITY PARADOX.Virtue A, Johnson C, Lopez-Pastraña J, Shao Y, Fu H, Li X, Li YF, Yin Y, Mai J, Rizzo V, Tordoff M, Bagi Z, Shan H, Jiang X, Wang H, Yang XF The Journal of biological chemistry, 2017 (292), 1267 - 1287 | | Submitted Externally | 27856635 | Published | |
| | | Submitted Externally | 28035044 | Published | |
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| Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism.Kory N, Grond S, Kamat SS, Li Z, Krahmer N, Chitraju C, Zhou P, Frohlich F, Semova I, Ejsing C, Zechner R, Cravatt BF, Farese RV, Walther TC Journal of lipid research, 2017 (58), 226 - 235 | | Submitted Externally | 27836991 | Published | |
| Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance.Williams AS, Trefts E, Lantier L, Grueter CA, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH Diabetes, 2017 (66), 325 - 334 | | Submitted Externally | 27899483 | Published | |
| | | | 27905063 | Published | |
| Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion.Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, Rabinowitz JD, Lazar MA, Sun Z Nature medicine, 2017 (23), 223 - 234 | | Submitted Externally | 27991918 | Published | |
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| | | | 28077357 | Published | |
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| Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation.Hasenour CM, Ridley DE, James FD, Hughey CC, Donahue EP, Viollet B, Foretz M, Young JD, Wasserman DH PLoS ONE, 2017 (12), e0170382 | | Submitted Externally | 28107516 | Published | |
| | | Submitted Externally | 28117404 | Published | |
| Prebiotic milk oligosaccharides prevent development of obese phenotype, impairment of gut permeability and microbial dysbiosis in high-fat fed mice.Hamilton MK, Ronveaux CC, Rust BM, Newman JW, Hawley M, Barile D, Mills DA, Raybould HE American journal of physiology. Gastrointestinal and liver physiology, 2017, ajpgi.0042 | | Submitted Externally | 28280143 | Published | |
| Dual CCR2/CCR5 antagonist treatment attenuates adipose inflammation, but not microvascular complications in ob/ob mice.O'Brien PD, Hinder LM, Parlee SD, Hayes JM, Backus C, Zhang H, Ma L, Sakowski SA, Brosius FC, Feldman EL Diabetes, obesity & metabolism, 2017 | | | 28332276 | Published | |
| | | Submitted Externally | 28403169 | Published | |
| Recovery of Vocal Fold Epithelium after Acute Phonotrauma.Rousseau B, Kojima T, Novaleski CK, Kimball EE, Valenzuela CV, Mizuta M, Daniero JJ, Garrett CG, Sivasankar MP Cells, tissues, organs, 2017 (204), 93 - 104 | | Submitted Externally | 28647731 | Published | |
| | | Submitted Externally | 28723568 | Published | |
| Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming.Guilherme A, Pedersen DJ, Henchey E, Henriques FS, Danai LV, Shen Y, Yenilmez B, Jung D, Kim JK, Lodhi IJ, Semenkovich CF, Czech MP Molecular metabolism, 2017 (6), 781 - 796 | | Submitted Externally | 28752043 | Published | |
| Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders.Chen Z, Wang GX, Ma SL, Jung DY, Ha H, Altamimi T, Zhao XY, Guo L, Zhang P, Hu CR, Cheng JX, Lopaschuk GD, Kim JK, Lin JD Molecular metabolism, 2017 (6), 863 - 872 | | Submitted Externally | 28752050 | Published | |
| | | Submitted Externally | 28793320 | Published | |
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| Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review.Ma X, Dai Z, Sun K, Zhang Y, Chen J, Yang Y, Tso P, Wu G, Wu Z Frontiers in immunology, 2017 (8), 1271 | | Submitted Externally | 29118753 | Published | |
| Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis.Gibbons SJ, Grover M, Choi KM, Wadhwa A, Zubair A, Wilson LA, Wu Y, Abell TL, Hasler WL, Koch KL, McCallum RW, Nguyen LAB, Parkman HP, Sarosiek I, Snape WJ, Tonascia J, Hamilton FA, Pasricha PJ, Farrugia G PLoS ONE, 2017 (12), e0187772 | | Submitted Externally | 29161307 | Published | |
| | | Submitted Externally | 29311772 | Published | |
| Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance.Dagdeviren S, Jung DY, Lee E, Friedline RH, Noh HL, Kim JH, Patel PR, Tsitsilianos N, Tsitsilianos AV, Tran DA, Tsougranis GH, Kearns CC, Uong CP, Kwon JY, Muller W, Lee KW, Kim JK Molecular and cellular biology, 2016 (36), 2956 - 2966 | | Submitted Externally | 27644327 | Published | |
| Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion.Syring KE, Boortz KA, Oeser JK, Ustione A, Platt KA, Shadoan MK, McGuinness OP, Piston DW, Powell DR, O'Brien RM Endocrinology, 2016 (157), 4534 - 4541 | | Submitted Externally | 27754787 | Published | |
| Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.DiStefano MT, Roth Flach RJ, Senol-Cosar O, Danai LV, Virbasius JV, Nicoloro SM, Straubhaar J, Dagdeviren S, Wabitsch M, Gupta OT, Kim JK, Czech MP Molecular metabolism, 2016 (5), 1149 - 1161 | | Submitted Externally | 27900258 | Published | |
| Implications of the differing roles of the ß1 and ß3 transmembrane and cytoplasmic domains for integrin function.Lu Z, Mathew S, Chen J, Hadziselimovic A, Palamuttam R, Hudson BG, Fässler R, Pozzi A, Sanders CR, Zent R eLife, 2016 (5) | | Submitted Externally | 27929375 | Published | |
| | | Submitted Externally | 28025129 | Published | |
| Antibiotics Suppress Activation of Intestinal Mucosal Mast Cells and Reduce Dietary Lipid Absorption in Sprague-Dawley Rats.Sato H, Zhang LS, Martinez K, Chang EB, Yang Q, Wang F, Howles PN, Hokari R, Miura S, Tso P Gastroenterology, 2016 (151), 923 - 932 | | Submitted Externally | 27436071 | Published | |
| Selection-, age-, and exercise-dependence of skeletal muscle gene expression patterns in a rat model of metabolic fitness.Ren YY, Koch LG, Britton SL, Qi NR, Treutelaar MK, Burant CF, Li JZ Physiological genomics, 2016 (48), 816 - 825 | | Submitted Externally | 27637250 | Published | |
| | | Submitted Externally | 27653037 | Published | |
| | | Submitted Externally | 27658726 | Published | |
| Local Delivery of PHD2 siRNA from ROS-Degradable Scaffolds to Promote Diabetic Wound Healing.Martin JR, Nelson CE, Gupta MK, Yu F, Sarett SM, Hocking KM, Pollins AC, Nanney LB, Davidson JM, Guelcher SA, Duvall CL Advanced healthcare materials, 2016 (5), 2751 - 2757 | | Submitted Externally | 27717176 | Published | |
| | | Submitted Externally | 27717208 | Published | |
| IL-10 prevents aging-associated inflammation and insulin resistance in skeletal muscle.Dagdeviren S, Jung DY, Friedline RH, Noh HL, Kim JH, Patel PR, Tsitsilianos N, Inashima K, Tran DA, Hu X, Loubato MM, Craige SM, Kwon JY, Lee KW, Kim JK FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016 | | Submitted Externally | 27811060 | Published | |
| SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise.Fujikawa T, Castorena CM, Pearson M, Kusminski CM, Ahmed N, Battiprolu PK, Kim KW, Lee S, Hill JA, Scherer PE, Holland WL, Elmquist JK eLife, 2016 (5) | | Submitted Externally | 27874828 | Published | |
| | | Submitted Externally | 27931321 | Published | |
| | | Submitted Externally | 27601468 | Published | |
| S-nitrosylation of endogenous protein tyrosine phosphatases in endothelial insulin signaling.Hsu MF, Pan KT, Chang FY, Khoo KH, Urlaub H, Cheng CF, Chang GD, Haj FG, Meng TC Free radical biology & medicine, 2016 (99), 199 - 213 | | Submitted Externally | 27521458 | Published | |
| | | Submitted Externally | 27555298 | Published | |
| | | Submitted Externally | 27689000 | Published | |
| Genome-wide compendium and functional assessment of in vivo heart enhancers.Dickel DE, Barozzi I, Zhu Y, Fukuda-Yuzawa Y, Osterwalder M, Mannion BJ, May D, Spurrell CH, Plajzer-Frick I, Pickle CS, Lee E, Garvin TH, Kato M, Akiyama JA, Afzal V, Lee AY, Gorkin DU, Ren B, Rubin EM, Visel A, Pennacchio LA Nature communications, 2016 (7), 12923 | | Submitted Externally | 27703156 | Published | |
| | | Submitted Externally | 27803394 | Published | |
| Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle.Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR American journal of respiratory and critical care medicine, 2016 (194), 719 - 28 | | Submitted Externally | 27077479 | Published | |
| | | Submitted Externally | 27209312 | Published | |
| | | Submitted Externally | 27344202 | Published | |
| Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti-MicroRNA Therapies.Beavers KR, Werfel TA, Shen T, Kavanaugh TE, Kilchrist KV, Mares JW, Fain JS, Wiese CB, Vickers KC, Weiss SM, Duvall CL Advanced materials (Deerfield Beach, Fla.), 2016 (28), 7984 - 7992 | | Submitted Externally | 27383910 | Published | |
| | | Submitted Externally | 27389691 | Published | |
| HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use.Ludvik AE, Pusec CM, Priyadarshini M, Angueira AR, Guo C, Lo A, Hershenhouse KS, Yang GY, Ding X, Reddy TE, Lowe WL, Layden BT Endocrinology, 2016 (157), 3452 - 61 | | Submitted Externally | 27459389 | Published | |
| | | Submitted Externally | 27548523 | Published | |
| High-throughput discovery of novel developmental phenotypes.Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE Nature, 2016 (537), 508 - 514 | | Submitted Externally | 27626380 | Published | |
| | | Submitted Externally | 27635635 | Published | |
| | | Submitted Externally | 27818713 | Published | |
| | | Submitted Externally | 28090564 | Published | |
| | | Submitted Externally | 28133633 | Published | |
| Bruton's Tyrosine Kinase Deficiency Inhibits Autoimmune Arthritis in Mice but Fails to Block Immune Complex-Mediated Inflammatory Arthritis.Nyhoff LE, Barron BL, Johnson EM, Bonami RH, Maseda D, Fensterheim BA, Han W, Blackwell TS, Crofford LJ, Kendall PL Arthritis & rheumatology (Hoboken, N.J.), 2016 (68), 1856 - 68 | | Submitted Externally | 26945549 | Published | |
| G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.Boortz KA, Syring KE, Dai C, Pound LD, Oeser JK, Jacobson DA, Wang JC, McGuinness OP, Powers AC, O'Brien RM Endocrinology, 2016 (157), 3002 - 8 | | Submitted Externally | 27300767 | Published | |
| | | Submitted Externally | 27535957 | Published | |
| Gold Nanoantenna-Mediated Photothermal Drug Delivery from Thermosensitive Liposomes in Breast Cancer.Ou YC, Webb JA, Faley S, Shae D, Talbert EM, Lin S, Cutright CC, Wilson JT, Bellan LM, Bardhan R ACS omega, 2016 (1), 234 - 243 | | Submitted Externally | 27656689 | Published | |
| Targeting I?B kinase ß in Adipocyte Lineage Cells for Treatment of Obesity and Metabolic Dysfunctions.Helsley RN, Sui Y, Park SH, Liu Z, Lee RG, Zhu B, Kern PA, Zhou C Stem cells (Dayton, Ohio), 2016 (34), 1883 - 95 | | Submitted Externally | 26991836 | Published | |
| Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development.Benjamin JT, van der Meer R, Im AM, Plosa EJ, Zaynagetdinov R, Burman A, Havrilla ME, Gleaves LA, Polosukhin VV, Deutsch GH, Yanagisawa H, Davidson JM, Prince LS, Young LR, Blackwell TS The American journal of pathology, 2016 (186), 1786 - 800 | | Submitted Externally | 27181406 | Published | |
| | | Submitted Externally | 27189169 | Published | |
| Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW Nature medicine, 2016 (22), 800 - 6 | | Submitted Externally | 27213816 | Published | |
| Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.Roth Flach RJ, Danai LV, DiStefano MT, Kelly M, Menendez LG, Jurczyk A, Sharma RB, Jung DY, Kim JH, Kim JK, Bortell R, Alonso LC, Czech MP The Journal of biological chemistry, 2016 (291), 16221 - 30 | | Submitted Externally | 27226575 | Published | |
| | | Submitted Externally | 27402952 | Published | |
| Perinatal triphenyl phosphate exposure accelerates type 2 diabetes onset and increases adipose accumulation in UCD-type 2 diabetes mellitus rats.Green AJ, Graham JL, Gonzalez EA, La Frano MR, Petropoulou SE, Park JS, Newman JW, Stanhope KL, Havel PJ, La Merrill MA Reproductive toxicology (Elmsford, N.Y.), 2016 | | Submitted Externally | 27421578 | Published | |
| | | Submitted Externally | 27320917 | Published | |
| Adolescents with or at ultra-high risk for bipolar disorder exhibit erythrocyte docosahexaenoic acid and eicosapentaenoic acid deficits: a candidate prodromal risk biomarker.McNamara RK, Jandacek R, Tso P, Blom TJ, Welge JA, Strawn JR, Adler CM, Strakowski SM, DelBello MP Early intervention in psychiatry, 2016 (10), 203 - 11 | | Submitted Externally | 26486098 | Published | |
| Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress.Mosinski JD, Pagadala MR, Mulya A, Huang H, Dan O, Shimizu H, Batayyah E, Pai RK, Schauer PR, Brethauer SA, Kirwan JP Acta physiologica (Oxford, England), 2016 (217), 141 - 51 | | Submitted Externally | 26663034 | Published | |
| Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction.Wanders D, Stone KP, Forney LA, Cortez CC, Dille KN, Simon J, Xu M, Hotard EC, Nikonorova IA, Pettit AP, Anthony TG, Gettys TW Diabetes, 2016 (65), 1499 - 510 | | Submitted Externally | 26936965 | Published | |
| | | Submitted Externally | 26993069 | Published | |
| Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways.Aung HH, Altman R, Nyunt T, Kim J, Nuthikattu S, Budamagunta M, Voss JC, Wilson D, Rutledge JC, Villablanca AC Journal of lipid research, 2016 (57), 955 - 68 | | Submitted Externally | 27087439 | Published | |
| | | Submitted Externally | 27094034 | Published | |
| Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice.Babaev VR, Yeung M, Erbay E, Ding L, Zhang Y, May JM, Fazio S, Hotamisligil GS, Linton MF Arteriosclerosis, thrombosis, and vascular biology, 2016 (36), 1122 - 31 | | Submitted Externally | 27102962 | Published | |
| | | Submitted Externally | 27133664 | Published | |
| Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice.Kang L, Mokshagundam S, Reuter B, Lark DS, Sneddon CC, Hennayake C, Williams AS, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH Diabetes, 2016 (65), 1590 - 600 | | Submitted Externally | 27207548 | Published | |
| Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury.Roychowdhury S, McCullough RL, Sanz-Garcia C, Saikia P, Alkhouri N, Matloob A, Pollard KA, McMullen MR, Croniger CM, Nagy LE Hepatology (Baltimore, Md.), 2016 | | Submitted Externally | 27301788 | Published | |
| Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, Torsitano C, McGraw TE, Puchowicz M, Kurland I, Karsenty G Cell Metabolism, 2016 (23), 1078 - 92 | | Submitted Externally | 27304508 | Published | |
| | | Submitted Externally | 27340841 | Published | |
| | | Submitted Externally | 26968208 | Published | |
| | | Submitted Externally | 26975707 | Published | |
| Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice.Jara A, Liu X, Sim D, Benner CM, Duran-Ortiz S, Qian Y, List EO, Berryman DE, Kim JK, Kopchick JJ Endocrinology, 2016 (157), 1929 - 41 | | Submitted Externally | 27035649 | Published | |
| | | Submitted Externally | 27117408 | Published | |
| Chronic Activation of ?2 AMPK Induces Obesity and Reduces ß Cell Function.Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martínez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Tóth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Feket Cell Metabolism, 2016 (23), 821 - 36 | | Submitted Externally | 27133129 | Published | |
| Insulin decreases atherosclerosis by inducing endothelin receptor B expression.Park K, Mima A, Li Q, Rask-Madsen C, He P, Mizutani K, Katagiri S, Maeda Y, Wu IH, Khamaisi M, Preil SR, Maddaloni E, Sørensen D, Rasmussen LM, Huang PL, King GL JCI insight, 2016 (1) | | Submitted Externally | 27200419 | Published | |
| Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA Nature communications, 2016 (7), 11365 | | Submitted Externally | 27098609 | Published | |
| | | Submitted Externally | 26842893 | Published | |
| Macrophage IKKa Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.Babaev VR, Ding L, Zhang Y, May JM, Lin PC, Fazio S, Linton MF Arteriosclerosis, thrombosis, and vascular biology, 2016 (36), 598 - 607 | | Submitted Externally | 26848161 | Published | |
| Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice.Ejaz A, Martinez-Guino L, Goldfine AB, Ribas-Aulinas F, De Nigris V, Ribó S, Gonzalez-Franquesa A, Garcia-Roves PM, Li E, Dreyfuss JM, Gall W, Kim JK, Bottiglieri T, Villarroya F, Gerszten RE, Patti ME, Lerin C Diabetes, 2016 (65), 902 - 12 | | Submitted Externally | 26858359 | Published | |
| ERa in Tac2 Neurons Regulates Puberty Onset in Female Mice.Greenwald-Yarnell ML, Marsh C, Allison MB, Patterson CM, Kasper C, MacKenzie A, Cravo R, Elias CF, Moenter SM, Myers MG Endocrinology, 2016 (157), 1555 - 65 | | Submitted Externally | 26862996 | Published | |
| Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin.Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH The Journal of clinical investigation, 2016 (126), 1425 - 37 | | Submitted Externally | 26927670 | Published | |
| | | Submitted Externally | 26949102 | Published | |
| PI3-kinase mutation linked to insulin and growth factor resistance in vivo.Winnay JN, Solheim MH, Dirice E, Sakaguchi M, Noh HL, Kang HJ, Takahashi H, Chudasama KK, Kim JK, Molven A, Kahn CR, Njølstad PR The Journal of clinical investigation, 2016 (126), 1401 - 12 | | Submitted Externally | 26974159 | Published | |
| | | Submitted Externally | 26976215 | Published | |
| Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins.Zhang W, Bu SY, Mashek MT, O-Sullivan I, Sibai Z, Khan SA, Ilkayeva O, Newgard CB, Mashek DG, Unterman TG Cell reports, 2016 (15), 349 - 59 | | Submitted Externally | 27050511 | Published | |
| Asprosin, a Fasting-Induced Glucogenic Protein Hormone.Romere C, Duerrschmid C, Bournat J, Constable P, Jain M, Xia F, Saha PK, Del Solar M, Zhu B, York B, Sarkar P, Rendon DA, Gaber MW, LeMaire SA, Coselli JS, Milewicz DM, Sutton VR, Butte NF, Moore DD, Chopra AR Cell, 2016 (165), 566 - 79 | | Submitted Externally | 27087445 | Published | |
| Accumulation of isolevuglandin-modified protein in normal and fibrotic lung.Mont S, Davies SS, Roberts Second LJ, Mernaugh RL, McDonald WH, Segal BH, Zackert W, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Massion PP, Marnett LJ, Travis EL, Freeman ML Scientific reports, 2016 (6), 24919 | | Submitted Externally | 27118599 | Published | |
| Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.Huang LH, Melton EM, Li H, Sohn P, Rogers MA, Mulligan-Kehoe MJ, Fiering SN, Hickey WF, Chang CC, Chang TY The Journal of biological chemistry, 2016 (291), 6232 - 44 | | Submitted Externally | 26801614 | Published | |
| | | Submitted Externally | 26467632 | Published | |
| Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016 (30), 1328 - 38 | | Submitted Externally | 26644351 | Published | |
| | | Submitted Externally | 26697982 | Published | |
| | | Submitted Externally | 26775176 | Published | |
| Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice.Min SY, Kady J, Nam M, Rojas-Rodriguez R, Berkenwald A, Kim JH, Noh HL, Kim JK, Cooper MP, Fitzgibbons T, Brehm MA, Corvera S Nature medicine, 2016 (22), 312 - 8 | | Submitted Externally | 26808348 | Published | |
| HIF2a Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.Ramakrishnan SK, Zhang H, Takahashi S, Centofanti B, Periyasamy S, Weisz K, Chen Z, Uhler MD, Rui L, Gonzalez FJ, Shah YM Cell Metabolism, 2016 (23), 505 - 16 | | Submitted Externally | 26853750 | Published | |
| Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury.Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ The Journal of nutritional biochemistry, 2016 (29), 12 - 20 | | Submitted Externally | 26895660 | Published | |
| | | Submitted Externally | 26903647 | Published | |
| The endothelial PHD2/HIF-2 axis regulates pulmonary artery pressure in mice.Kapitsinou PP, Rajendran G, Astleford L, Michael M, Schonfeld MP, Fields T, Shay S, French JL, West J, Haase VH Molecular and cellular biology, 2016 | | Submitted Externally | 26976644 | Published | |
| miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.Riquelme I, Tapia O, Leal P, Sandoval A, Varga MG, Letelier P, Buchegger K, Bizama C, Espinoza JA, Peek RM, Araya JC, Roa JC Cellular oncology (Dordrecht), 2016 (39), 23 - 33 | | Submitted Externally | 26458815 | Published | |
| p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment.Saxon JA, Cheng DS, Han W, Polosukhin VV, McLoed AG, Richmond BW, Gleaves LA, Tanjore H, Sherrill TP, Barham W, Yull FE, Blackwell TS Journal of immunology (Baltimore, Md. : 1950), 2016 (196), 1891 - 9 | | Submitted Externally | 26773153 | Published | |
| Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion.Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP Nature communications, 2016 (7), 10686 | | Submitted Externally | 26880110 | Published | |
| | | Submitted Externally | 26420862 | Published | |
| The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice.Ceddia RP, Lee D, Maulis MF, Carboneau BA, Threadgill DW, Poffenberger G, Milne G, Boyd KL, Powers AC, McGuinness OP, Gannon M, Breyer RM Endocrinology, 2016 (157), 220 - 32 | | Submitted Externally | 26485614 | Published | |
| Cytochrome P450 1B1 Contributes to the Development of Atherosclerosis and Hypertension in Apolipoprotein E-Deficient Mice.Song CY, Ghafoor K, Ghafoor HU, Khan NS, Thirunavukkarasu S, Jennings BL, Estes AM, Zaidi S, Bridges D, Tso P, Gonzalez FJ, Malik KU Hypertension, 2016 (67), 206 - 13 | | Submitted Externally | 26573711 | Published | |
| Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2).Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, Jung DY, Lee Y, Kitamura T, Ergun S, Kulkarni RN, Kim JK, Giovannucci DR, Najjar SM The Journal of biological chemistry, 2016 (291), 980 - 8 | | Submitted Externally | 26586918 | Published | |
| Immune activation caused by vascular oxidation promotes fibrosis and hypertension.Wu J, Saleh MA, Kirabo A, Itani HA, Montaniel KR, Xiao L, Chen W, Mernaugh RL, Cai H, Bernstein KE, Goronzy JJ, Weyand CM, Curci JA, Barbaro NR, Moreno H, Davies SS, Roberts LJ, Madhur MS, Harrison DG The Journal of clinical investigation, 2016 (126), 50 - 67 | | Submitted Externally | 26595812 | Published | |
| Nanoformulated copper/zinc superoxide dismutase reduces adipose inflammation in obesity.Perriotte-Olson C, Adi N, Manickam DS, Westwood RA, Desouza CV, Natarajan G, Crook A, Kabanov AV, Saraswathi V Obesity (Silver Spring, Md.), 2016 (24), 148 - 56 | | Submitted Externally | 26612356 | Published | |
| | | Submitted Externally | 26684088 | Published | |
| The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity.Dooley J, Garcia-Perez JE, Sreenivasan J, Schlenner SM, Vangoitsenhoven R, Papadopoulou AS, Tian L, Schonefeldt S, Serneels L, Deroose C, Staats KA, Van der Schueren B, De Strooper B, McGuinness OP, Mathieu C, Liston A Diabetes, 2016 (65), 53 - 61 | | Submitted Externally | 26696639 | Published | |
| EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer.Amato KR, Wang S, Tan L, Hastings AK, Song W, Lovly CM, Meador CB, Ye F, Lu P, Balko JM, Colvin DC, Cates JM, Pao W, Gray NS, Chen J Cancer research, 2016 (76), 305 - 18 | | Submitted Externally | 26744526 | Published | |
| Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates Pro-Opiomelanocortin Neurons in the Arcuate Nucleus.Yan C, He Y, Xu Y, Shu G, Wang C, Yang Y, Saito K, Xu P, Hinton AO, Yan X, Yu L, Wu Q, Tso P, Tong Q, Xu Y Neuroendocrinology, 2016 (103), 476 - 88 | | Submitted Externally | 26337236 | Published | |
| Highly differentiated human airway epithelial cells: a model to study host cell-parasite interactions in pertussis.Guevara C, Zhang C, Gaddy JA, Iqbal J, Guerra J, Greenberg DP, Decker MD, Carbonetti N, Starner TD, McCray PB, Mooi FR, Gómez-Duarte OG Infectious diseases (London, England), 2016 (48), 177 - 88 | | Submitted Externally | 26492208 | Published | |
| Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress.Vernia S, Morel C, Madara JC, Cavanagh-Kyros J, Barrett T, Chase K, Kennedy NJ, Jung DY, Kim JK, Aronin N, Flavell RA, Lowell BB, Davis RJ eLife, 2016 (5), e10031 | | Submitted Externally | 26910012 | Published | |
| Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways.Ryczko MC, Pawling J, Chen R, Abdel Rahman AM, Yau K, Copeland JK, Zhang C, Surendra A, Guttman DS, Figeys D, Dennis JW Scientific reports, 2016 (6), 23043 | | Submitted Externally | 26972830 | Published | |
| | | Submitted Externally | 27011175 | Published | |
| VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications.Robciuc MR, Kivelä R, Williams IM, de Boer JF, van Dijk TH, Elamaa H, Tigistu-Sahle F, Molotkov D, Leppänen VM, Käkelä R, Eklund L, Wasserman DH, Groen AK, Alitalo K Cell Metabolism, 2016 (23), 712 - 24 | | | 27076080 | Published | |
| Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens.Shaffer CL, Good JA, Kumar S, Krishnan KS, Gaddy JA, Loh JT, Chappell J, Almqvist F, Cover TL, Hadjifrangiskou M mBio, 2016 (7), e00221 - 16 | | Submitted Externally | 27118587 | Published | |
| Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice.Costa DK, Huckestein BR, Edmunds LR, Petersen MC, Nasiri A, Butrico GM, Abulizi A, Harmon DB, Lu C, Mantell BS, Hartman DJ, Camporez JP, O'Doherty RM, Cline GW, Shulman GI, Jurczak MJ American journal of physiology. Endocrinology and metabolism, 2016 (311), E105 - 16 | | Submitted Externally | 27166280 | Published | |
| Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.Vazirani RP, Verma A, Sadacca LA, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K, Camporez JP, Moreira G, Falcone DJ, Accili D, Elemento O, Shulman GI, Kahn BB, McGraw TE Diabetes, 2016 (65), 1577 - 89 | | Submitted Externally | 27207531 | Published | |
| | | Submitted Externally | 27239296 | Published | |
| Hepatic and Whole-Body Insulin Metabolism during Proestrus and Estrus in Mongrel Dogs.Yu EN, Winnick JJ, Edgerton DS, Scott MF, Smith MS, Farmer B, Williams PE, Cherrington AD, Moore MC Comparative medicine, 2016 (66), 235 - 40 | | Submitted Externally | 27298249 | Published | |
| | | Submitted Externally | 27354419 | Published | |
| IRF3 promotes adipose inflammation and insulin resistance and represses browning.Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED The Journal of clinical investigation, 2016 (126), 2839 - 54 | | Submitted Externally | 27400129 | Published | |
| Lymphoblastoid Cell Lines as a Tool to Study Inter-Individual Differences in the Response to Glucose.Grassi MA, Rao VR, Chen S, Cao D, Gao X, Cleary PA, Huang RS, Paterson AD, Natarajan R, Rehman J, Kern TS, PLoS ONE, 2016 (11), e0160504 | | Submitted Externally | 27509144 | Published | |
| | | | 27511834 | Published | |
| | | Submitted Externally | 27537846 | Published | |
| ChREBP regulates fructose-induced glucose production independently of insulin signaling.Kim MS, Krawczyk SA, Doridot L, Fowler AJ, Wang JX, Trauger SA, Noh HL, Kang HJ, Meissen JK, Blatnik M, Kim JK, Lai M, Herman MA The Journal of clinical investigation, 2016 | | Submitted Externally | 27669460 | Published | |
| | | Submitted Externally | 27676071 | Published | |
| | | Submitted Externally | 27689415 | Published | |
| Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L Neuron, 2016 (92), 392 - 406 | | Submitted Externally | 27693255 | Published | |
| Characterization of a caveolin-1 mutation associated with both pulmonary arterial hypertension and congenital generalized lipodystrophy.Han B, Copeland CA, Kawano Y, Rosenzweig EB, Austin ED, Shahmirzadi L, Tang S, Raghunathan K, Chung WK, Kenworthy AK Traffic (Copenhagen, Denmark), 2016 (17), 1297 - 1312 | | Submitted Externally | 27717241 | Published | |
| | | Submitted Externally | 26438821 | Published | |
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| First-episode bipolar disorder is associated with erythrocyte membrane docosahexaenoic acid deficits: Dissociation from clinical response to lithium or quetiapine.McNamara RK, Jandacek R, Tso P, Blom TJ, Welge JA, Strawn JR, Adler CM, DelBello MP, Strakowski SM Psychiatry research, 2015 (230), 447 - 53 | | Submitted Externally | 26477955 | Published | |
| | | Submitted Externally | 26505974 | Published | |
| Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.Singh V, Chassaing B, Zhang L, San Yeoh B, Xiao X, Kumar M, Baker MT, Cai J, Walker R, Borkowski K, Harvatine KJ, Singh N, Shearer GC, Ntambi JM, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M Cell Metabolism, 2015 (22), 983 - 96 | | Submitted Externally | 26525535 | Published | |
| Relative contributions of L-FABP, SCP-2/SCP-x, or both to hepatic biliary phenotype of female mice.Martin GG, Landrock D, Landrock KK, Howles PN, Atshaves BP, Kier AB, Schroeder F Archives of biochemistry and biophysics, 2015 (588), 25 - 32 | | Submitted Externally | 26541319 | Published | |
| | | Submitted Externally | 26580240 | Published | |
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| Enhanced Glucose Transport, but not Phosphorylation Capacity, Ameliorates Lipopolysaccharide-Induced Impairments in Insulin Stimulated-Muscle Glucose Uptake.Otero YF, Mulligan KX, Barnes TM, Ford EA, Malabanan CM, Zong H, Pessin JE, Wasserman DH, McGuinness OP Shock (Augusta, Ga.), 2015 | | Submitted Externally | 26682946 | Published | |
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| FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance.Nuotio-Antar AM, Poungvarin N, Li M, Schupp M, Mohammad M, Gerard S, Zou F, Chan L Endocrinology, 2015 (156), 4020 - 32 | | Submitted Externally | 26248218 | Published | |
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| NF-?B-dependent airway inflammation triggers systemic insulin resistance.Cyphert TJ, Morris RT, House LM, Barnes TM, Otero YF, Barham WJ, Hunt RP, Zaynagetdinov R, Yull FE, Blackwell TS, McGuinness OP American journal of physiology. Regulatory, integrative and comparative physiology, 2015 (309), R1144 - 52 | | Submitted Externally | 26377563 | Published | |
| | | Submitted Externally | 26446275 | Published | |
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| [(11)C]acetate PET Imaging is not Always Associated with Increased Lipogenesis in Hepatocellular Carcinoma in Mice.Li L, Che L, Wang C, Blecha JE, Li X, VanBrocklin HF, Calvisi DF, Puchowicz M, Chen X, Seo Y Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2015 | | Submitted Externally | 26567114 | Published | |
| | | Submitted Externally | 26629410 | Published | |
| Endothelial-to-mesenchymal transition drives atherosclerosis progression.Chen PY, Qin L, Baeyens N, Li G, Afolabi T, Budatha M, Tellides G, Schwartz MA, Simons M The Journal of clinical investigation, 2015 (125), 4514 - 28 | | Submitted Externally | 26517696 | Published | |
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| Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes.Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Allen EJ, Donahue EP, Rivera N, Winnick JJ, Edgerton DS, Nishimura E, Fledelius C, Brand CL, Cherrington AD Diabetes, 2015 (64), 3439 - 51 | | Submitted Externally | 26085570 | Published | |
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| | | | 26381349 | In press | |
| Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice.Cordoba-Chacon J, Majumdar N, List EO, Diaz-Ruiz A, Frank SJ, Manzano A, Bartrons R, Puchowicz M, Kopchick JJ, Kineman RD Diabetes, 2015 (64), 3093 - 103 | | Submitted Externally | 26015548 | Published | |
| | | Submitted Externally | 26072363 | Published | |
| | | Submitted Externally | 26149094 | Published | |
| Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.Yamamoto S, Zhong J, Yancey PG, Zuo Y, Linton MF, Fazio S, Yang H, Narita I, Kon V Atherosclerosis, 2015 (242), 56 - 64 | | Submitted Externally | 26184694 | Published | |
| | | Submitted Externally | 26374090 | Published | |
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| Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification.Yuasa M, Mignemi NA, Nyman JS, Duvall CL, Schwartz HS, Okawa A, Yoshii T, Bhattacharjee G, Zhao C, Bible JE, Obremskey WT, Flick MJ, Degen JL, Barnett JV, Cates JM, Schoenecker JG The Journal of clinical investigation, 2015 (125), 3117 - 31 | | | 26214526 | Published | |
| Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.Bettaieb A, Jiang JX, Sasaki Y, Chao TI, Kiss Z, Chen X, Tian J, Katsuyama M, Yabe-Nishimura C, Xi Y, Szyndralewiez C, Schroder K, Shah A, Brandes RP, Haj FG, Torok NJ Gastroenterology, 2015 (149), 468 - 80.e10 | | Submitted Externally | 25888330 | Published | |
| Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance.Lee E, Jung DY, Kim JH, Patel PR, Hu X, Lee Y, Azuma Y, Wang HF, Tsitsilianos N, Shafiq U, Kwon JY, Lee HJ, Lee KW, Kim JK FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015 (29), 3182 - 92 | | Submitted Externally | 25888600 | Published | |
| Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance.Al-Share QY, DeAngelis AM, Lester SG, Bowman TA, Ramakrishnan SK, Abdallah SL, Russo L, Patel PR, Kaw MK, Raphael CK, Kim AJ, Heinrich G, Lee AD, Kim JK, Kulkarni RN, Philbrick WM, Najjar SM Diabetes, 2015 (64), 2780 - 90 | | Submitted Externally | 25972571 | Published | |
| Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories.Hwang HS, Kryshtal DO, Feaster TK, Sánchez-Freire V, Zhang J, Kamp TJ, Hong CC, Wu JC, Knollmann BC Journal of molecular and cellular cardiology, 2015 (85), 79 - 88 | | Submitted Externally | 25982839 | Published | |
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| Increased high-density lipoprotein cholesterol levels in mice with XX versus XY sex chromosomes.Link JC, Chen X, Prien C, Borja MS, Hammerson B, Oda MN, Arnold AP, Reue K Arteriosclerosis, thrombosis, and vascular biology, 2015 (35), 1778 - 86 | | Submitted Externally | 26112012 | Published | |
| | | Submitted Externally | 26152729 | Published | |
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| The role of apolipoprotein A-IV (apoA-IV) in regulating glucagon-like peptide (GLP)-1 secretion.Wang F, Yang Q, Huesman S, Xu M, Li X, Lou D, Woods SC, Marziano C, Tso P American journal of physiology. Gastrointestinal and liver physiology, 2015, ajpgi.0007 | | Submitted Externally | 26294669 | Published | |
| | | Submitted Externally | 26323691 | Published | |
| | | Submitted Externally | 25827057 | Published | |
| Short-term food restriction followed by controlled refeeding promotes gorging behavior, enhances fat deposition, and diminishes insulin sensitivity in mice.Kliewer KL, Ke JY, Lee HY, Stout MB, Cole RM, Samuel VT, Shulman GI, Belury MA The Journal of nutritional biochemistry, 2015 (26), 721 - 728 | | | 25913018 | Published | |
| | | Submitted Externally | 25918248 | Published | |
| | | | 26004886 | Published | |
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| A major role of insulin in promoting obesity-associated adipose tissue inflammation.Pedersen DJ, Guilherme A, Danai LV, Heyda L, Matevossian A, Cohen J, Nicoloro SM, Straubhaar J, Noh HL, Jung D, Kim JK, Czech MP Molecular metabolism, 2015 (4), 507 - 18 | | Submitted Externally | 26137438 | Published | |
| Precision medicine: Look to the mice.Lloyd KC, Meehan T, Beaudet A, Murray S, Svenson K, McKerlie C, West D, Morse I, Parkinson H, Brown S, Mallon AM, Moore M Science (New York, N.Y.), 2015 (349), 390 | | Submitted Externally | 26206923 | Published | |
| Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/ßKlotho Complex.Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RA, Dunshee DR, Wu AL, Haley B, Anderson K, Warming S, Rairdan XY, Lewin-Koh N, Zhang Y, Gutierrez J, Baruch A, Gelzleichter TR, Stevens D, Rajan S, Bainbridge TW, Vernes JM, Meng YG, Ziai J, Soriano RH, Brauer MJ, Chen Y, Stawicki S, Kim HS, Comps-Agrar L, Luis E, Spiess C, Wu Y, Ernst JA, McGuinness OP, Peterson AS, Sonoda J EBioMedicine, 2015 (2), 730 - 43 | | Submitted Externally | 26288846 | Published | |
| Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5.Zhang Y, Nguyen T, Tang P, Kennedy NJ, Jiao H, Zhang M, Reynolds JM, Jaeschke A, Martin-Orozco N, Chung Y, He WM, Wang C, Jia W, Ge B, Davis RJ, Flavell RA, Dong C The Journal of biological chemistry, 2015 (290), 14875 - 83 | | Submitted Externally | 25922079 | Published | |
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| | | | 25552595 | Published | |
| Dipeptidyl peptidase-4 inhibition ameliorates Western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function.Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS Diabetes, 2015 (64), 1988 - 2001 | | Submitted Externally | 25605806 | Published | |
| UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity.Wanders D, Burk DH, Cortez CC, Van NT, Stone KP, Baker M, Mendoza T, Mynatt RL, Gettys TW FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015 (29), 2603 - 2615 | | | 25742717 | Published | |
| | | Submitted Externally | 25898954 | Published | |
| Coordinated Regulation of Vasopressin Inactivation and Glucose Uptake by Action of TUG Protein in Muscle.Habtemichael EN, Alcázar-Román A, Rubin BR, Grossi LR, Belman JP, Julca O, Loffler MG, Li H, Chi NW, Samuel VT, Bogan JS The Journal of biological chemistry, 2015 (290), 14454 - 61 | | Submitted Externally | 25944897 | Published | |
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| Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.Fu S, Yalcin A, Lee GY, Li P, Fan J, Arruda AP, Pers BM, Yilmaz M, Eguchi K, Hotamisligil GS Science translational medicine, 2015 (7), 292ra98 | | Submitted Externally | 26084805 | Published | |
| Glial Expression of the Caenorhabditis elegans Gene swip-10 Supports Glutamate Dependent Control of Extrasynaptic Dopamine Signaling.Hardaway JA, Sturgeon SM, Snarrenberg CL, Li Z, Xu XZ, Bermingham DP, Odiase P, Spencer WC, Miller DM, Carvelli L, Hardie SL, Blakely RD The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015 (35), 9409 - 23 | | Submitted Externally | 26109664 | Published | |
| Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells.Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M Cell stem cell, 2015 (16), 477 - 487 | | | 25957903 | Published | |
| | | | 25948682 | Published | |
| Central serotonergic neurons activate and recruit thermogenic brown and beige fat and regulate glucose and lipid homeostasis.McGlashon JM, Gorecki MC, Kozlowski AE, Thirnbeck CK, Markan KR, Leslie KL, Kotas ME, Potthoff MJ, Richerson GB, Gillum MP Cell Metabolism, 2015 (21), 692 - 705 | | | 25955206 | Published | |
| TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess.Idrissova L, Malhi H, Werneburg NW, LeBrasseur NK, Bronk SF, Fingas C, Tchkonia T, Pirtskhalava T, White TA, Stout MB, Hirsova P, Krishnan A, Liedtke C, Trautwein C, Finnberg N, El-Deiry WS, Kirkland JL, Gores GJ Journal of hepatology, 2015 (62), 1156 - 1163 | | Submitted Externally | 25445398 | Published | |
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| Endothelial uncoupling protein 2 regulates mitophagy and pulmonary hypertension during intermittent hypoxia.Haslip M, Dostanic I, Huang Y, Zhang Y, Russell KS, Jurczak MJ, Mannam P, Giordano F, Erzurum SC, Lee PJ Arteriosclerosis, thrombosis, and vascular biology, 2015 (35), 1166 - 78 | | Submitted Externally | 25814675 | Published | |
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| p53 enables metabolic fitness and self-renewal of nephron progenitor cells.Li Y, Liu J, Li W, Brown A, Baddoo M, Li M, Carroll T, Oxburgh L, Feng Y, Saifudeen Z Development (Cambridge, England), 2015 (142), 1228 - 1241 | | Submitted Externally | 25804735 | Published | |
| Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice.Krüger J, Brachs S, Trappiel M, Kintscher U, Meyborg H, Wellnhofer E, Thöne-Reineke C, Stawowy P, Östman A, Birkenfeld AL, Böhmer FD, Kappert K Molecular metabolism, 2015 (4), 325 - 336 | | Submitted Externally | 25830095 | Published | |
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| | | | 25801033 | Published | |
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| Activation of muscular TrkB by its small molecular agonist 7,8-dihydroxyflavone sex-dependently regulates energy metabolism in diet-induced obese mice.Chan CB, Tse MC, Liu X, Zhang S, Schmidt R, Otten R, Liu L, Ye K Chemistry & biology, 2015 (22), 355 - 368 | | | 25754472 | Published | |
| | | Submitted Externally | 25778920 | Published | |
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| A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease.Spinale JM, Mariani LH, Kapoor S, Zhang J, Weyant R, Song PX, Wong HN, Troost JP, Gadegbeku CA, Gipson DS, Kretzler M, Nihalani D, Holzman LB Kidney international, 2015 (87), 564 - 574 | | | 25354239 | Published | |
| Low levels of lipopolysaccharide modulate mitochondrial oxygen consumption in skeletal muscle.Frisard MI, Wu Y, McMillan RP, Voelker KA, Wahlberg KA, Anderson AS, Boutagy N, Resendes K, Ravussin E, Hulver MW Metabolism: clinical and experimental, 2015 (64), 416 - 427 | | Submitted Externally | 25528444 | Published | |
| ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content.Camporez JP, Kanda S, Petersen MC, Jornayvaz FR, Samuel VT, Bhanot S, Petersen KF, Jurczak MJ, Shulman GI Journal of lipid research, 2015 (56), 526 - 36 | | Submitted Externally | 25548259 | Published | |
| Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL.Tavori H, Su YR, Yancey PG, Giunzioni I, Wilhelm AJ, Blakemore JL, Zabalawi M, Linton MF, Sorci-Thomas MG, Fazio S Journal of lipid research, 2015 (56), 635 - 643 | | | 25593328 | Published | |
| | | Submitted Externally | 25721504 | Published | |
| Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated control of type 1 pili.Floyd KA, Moore JL, Eberly AR, Good JA, Shaffer CL, Zaver H, Almqvist F, Skaar EP, Caprioli RM, Hadjifrangiskou M PLoS pathogens, 2015 (11), e1004697 | | Submitted Externally | 25738819 | Published | |
| Arrestins regulate cell spreading and motility via focal adhesion dynamics.Cleghorn WM, Branch KM, Kook S, Arnette C, Bulus N, Zent R, Kaverina I, Gurevich EV, Weaver AM, Gurevich VV Molecular biology of the cell, 2015 (26), 622 - 635 | | Submitted Externally | 25540425 | Published | |
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| Adjuvant neurotrophic factors in peripheral nerve repair with chondroitin sulfate proteoglycan-reduced acellular nerve allografts.Boyer RB, Sexton KW, Rodriguez-Feo CL, Nookala R, Pollins AC, Cardwell NL, Tisdale KY, Nanney LB, Shack RB, Thayer WP The Journal of surgical research, 2015 (193), 969 - 977 | | Submitted Externally | 25438961 | Published | |
| | | | 25449986 | Published | |
| Reactive ?-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT Journal of molecular and cellular cardiology, 2015 (79), 295 - 302 | | Submitted Externally | 25463275 | Published | |
| Dysfunctional high-density lipoproteins in children with chronic kidney disease.Kaseda R, Jabs K, Hunley TE, Jones D, Bian A, Allen RM, Vickers KC, Yancey PG, Linton MF, Fazio S, Kon V Metabolism: clinical and experimental, 2015 (64), 263 - 273 | | Submitted Externally | 25467845 | Published | |
| | | Submitted Externally | 25473044 | Published | |
| ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease.Poole KM, Nelson CE, Joshi RV, Martin JR, Gupta MK, Haws SC, Kavanaugh TE, Skala MC, Duvall CL Biomaterials, 2015 (41), 166 - 175 | | Submitted Externally | 25522975 | Published | |
| Residues required for phosphorylation of translation initiation factor eIF2a under diverse stress conditions are divergent between yeast and human.Majumder M, Mitchell D, Merkulov S, Wu J, Guan BJ, Snider MD, Krokowski D, Yee VC, Hatzoglou M The international journal of biochemistry & cell biology, 2015 (59), 135 - 141 | | | 25541374 | Published | |
| Acetylation of TUG protein promotes the accumulation of GLUT4 glucose transporters in an insulin-responsive intracellular compartment.Belman JP, Bian RR, Habtemichael EN, Li DT, Jurczak MJ, Alcázar-Román A, McNally LJ, Shulman GI, Bogan JS The Journal of biological chemistry, 2015 (290), 4447 - 63 | | Submitted Externally | 25561724 | Published | |
| | | Submitted Externally | 25565226 | Published | |
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| An ERK/Cdk5 axis controls the diabetogenic actions of PPAR?.Banks AS, McAllister FE, Camporez JP, Zushin PJ, Jurczak MJ, Laznik-Bogoslavski D, Shulman GI, Gygi SP, Spiegelman BM Nature, 2015 (517), 391 - 395 | | | 25409143 | Published | |
| Dual MMP7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery.Li H, Miteva M, Kirkbride KC, Cheng MJ, Nelson CE, Simpson EM, Gupta MK, Duvall CL, Giorgio TD Biomacromolecules, 2015 (16), 192 - 201 | | Submitted Externally | 25414930 | Published | |
| | | Submitted Externally | 25298529 | Published | |
| Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice.Xi Y, Liu S, Bettaieb A, Matsuo K, Matsuo I, Hosein E, Chahed S, Wiede F, Zhang S, Zhang ZY, Kulkarni RN, Tiganis T, Haj FG Diabetologia, 2015 (58), 122 - 31 | | Submitted Externally | 25338551 | Published | |
| Deficiency of the tumor promoter gene wip1 induces insulin resistance.Armata HL, Chamberland S, Watts L, Ko HJ, Lee Y, Jung DY, Kim JK, Sluss HK Molecular endocrinology (Baltimore, Md.), 2015 (29), 28 - 39 | | Submitted Externally | 25379953 | Published | |
| Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers.Miteva M, Kirkbride KC, Kilchrist KV, Werfel TA, Li H, Nelson CE, Gupta MK, Giorgio TD, Duvall CL Biomaterials, 2015 (38), 97 - 107 | | Submitted Externally | 25453977 | Published | |
| Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids.Vatner DF, Majumdar SK, Kumashiro N, Petersen MC, Rahimi Y, Gattu AK, Bears M, Camporez JP, Cline GW, Jurczak MJ, Samuel VT, Shulman GI Proceedings of the National Academy of Sciences of the United States of America, 2015 (112), 1143 - 8 | | Submitted Externally | 25564660 | Published | |
| | | Submitted Externally | 25646557 | Published | |
| Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis.Lawan A, Zhang L, Gatzke F, Min K, Jurczak MJ, Al-Mutairi M, Richter P, Camporez JP, Couvillon A, Pesta D, Roth Flach RJ, Shulman GI, Bennett AM Molecular and cellular biology, 2015 (35), 26 - 40 | | Submitted Externally | 25312648 | Published | |
| Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice.Zhou L, Park SY, Xu L, Xia X, Ye J, Su L, Jeong KH, Hur JH, Oh H, Tamori Y, Zingaretti CM, Cinti S, Argente J, Yu M, Wu L, Ju S, Guan F, Yang H, Choi CS, Savage DB, Li P Nature communications, 2015 (6), 5949 | | Submitted Externally | 25565658 | Published | |
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| Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.Perry RJ, Camporez JP, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI Cell, 2015 (160), 745 - 58 | | Submitted Externally | 25662011 | Published | |
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| Metabolic plasticity in resting and thrombin activated platelets.Ravi S, Chacko B, Sawada H, Kramer PA, Johnson MS, Benavides GA, O'Donnell V, Marques MB, Darley-Usmar VM PLoS ONE, 2015 (10), e0123597 | | Submitted Externally | 25875958 | Published | |
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| FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.O-Sullivan I, Zhang W, Wasserman DH, Liew CW, Liu J, Paik J, DePinho RA, Stolz DB, Kahn CR, Schwartz MW, Unterman TG Nature communications, 2015 (6), 7079 | | | 25963540 | Published | |
| | | Submitted Externally | 25968605 | Published | |
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| Circadian control of bile acid synthesis by a KLF15-Fgf15 axis.Han S, Han SS, Zhang R, Jain R, Shi H, Zhang L, Zhou G, Sangwung P, Tugal D, Atkins GB, Prosdocimo DA, Lu Y, Han X, Tso P, Liao X, Epstein JA, Jain MK Nature communications, 2015 (6), 7231 - 7 | | | 26040986 | Published | |
| Sensitization of Chemo-Resistant Human Chronic Myeloid Leukemia Stem-Like Cells to Hsp90 Inhibitor by SIRT1 Inhibition.Kim HB, Lee SH, Um JH, Kim MJ, Hyun SK, Gong EJ, Oh WK, Kang CD, Kim SH International journal of biological sciences, 2015 (11), 923 - 934 | | Submitted Externally | 26157347 | Published | |
| Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic ß cell insufficiency.Lorenzo DN, Healy JA, Hostettler J, Davis J, Yang J, Wang C, Hohmeier HE, Zhang M, Bennett V The Journal of clinical investigation, 2015 (125), 3087 - 102 | | Submitted Externally | 26168218 | Published | |
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| Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery.Flynn CR, Albaugh VL, Cai S, Cheung-Flynn J, Williams PE, Brucker RM, Bordenstein SR, Guo Y, Wasserman DH, Abumrad NN Nature communications, 2015 (6), 7715 | | Submitted Externally | 26197299 | Published | |
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| Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals.Zhou H, Lei X, Benson T, Mintz J, Xu X, Harris RB, Weintraub NL, Wang X, Chen W Journal of lipid research, 2015 (56), 1912 - 25 | | Submitted Externally | 26269358 | Published | |
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| Safety of Striatal Infusion of siRNA in a Transgenic Huntington's Disease Mouse Model.Johnson E, Chase K, McGowan S, Mondo E, Pfister E, Mick E, Friedline RH, Kim JK, Sapp E, DiFiglia M, Aronin N Journal of Huntington's disease, 2015 (4), 219 - 29 | | | 26444021 | Published | |
| | | Submitted Externally | 26464581 | Published | |
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| Glucocorticoids enhance muscle endurance and ameliorate Duchenne muscular dystrophy through a defined metabolic program.Morrison-Nozik A, Anand P, Zhu H, Duan Q, Sabeh M, Prosdocimo DA, Lemieux ME, Nordsborg N, Russell AP, MacRae CA, Gerber AN, Jain MK, Haldar SM Proceedings of the National Academy of Sciences of the United States of America, 2015 (112), E6780 - 9 | | Submitted Externally | 26598680 | Published | |
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| The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes.Sisler JD, Morgan M, Raje V, Grande RC, Derecka M, Meier J, Cantwell M, Szczepanek K, Korzun WJ, Lesnefsky EJ, Harris TE, Croniger CM, Larner AC PLoS ONE, 2015 (10), e0144444 | | Submitted Externally | 26689548 | Published | |
| Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.Cossette SM, Gastonguay AJ, Bao X, Lerch-Gaggl A, Zhong L, Harmann LM, Koceja C, Miao RQ, Vakeel P, Chun C, Li K, Foeckler J, Bordas M, Weiler H, Strande J, Palecek SP, Ramchandran R Biology open, 2014 | | | 25505152 | Published | |
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| A parabrachial-hypothalamic cholecystokinin neurocircuit controls counterregulatory responses to hypoglycemia.Garfield AS, Shah BP, Madara JC, Burke LK, Patterson CM, Flak J, Neve RL, Evans ML, Lowell BB, Myers MG, Heisler LK Cell Metabolism, 2014 (20), 1030 - 1037 | | Submitted Externally | 25470549 | Published | |
| Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis.Fang P, Zhang D, Cheng Z, Yan C, Jiang X, Kruger WD, Meng S, Arning E, Bottiglieri T, Choi ET, Han Y, Yang XF, Wang H Diabetes, 2014 (63), 4275 - 90 | | Submitted Externally | 25008174 | Published | |
| Mitochondrial GTP insensitivity contributes to hypoglycemia in hyperinsulinemia hyperammonemia by inhibiting glucagon release.Kibbey RG, Choi CS, Lee HY, Cabrera O, Pongratz RL, Zhao X, Birkenfeld AL, Li C, Berggren PO, Stanley C, Shulman GI Diabetes, 2014 (63), 4218 - 29 | | Submitted Externally | 25024374 | Published | |
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| Shc depletion stimulates brown fat activity in vivo and in vitro.Tomilov A, Bettaieb A, Kim K, Sahdeo S, Tomilova N, Lam A, Hagopian K, Connell M, Fong J, Rowland D, Griffey S, Ramsey J, Haj F, Cortopassi G Aging cell, 2014 (13), 1049 - 58 | | Submitted Externally | 25257068 | Published | |
| Identification of small proline-rich repeat protein 3 as a novel atheroprotective factor that promotes adaptive Akt signaling in vascular smooth muscle cells.Segedy AK, Pyle AL, Li B, Zhang Y, Babaev VR, Jat P, Fazio S, Atkinson JB, Linton MF, Young PP Arteriosclerosis, thrombosis, and vascular biology, 2014 (34), 2527 - 2536 | | | 25278290 | Published | |
| The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells.Gao Y, Wu F, Zhou J, Yan L, Jurczak MJ, Lee HY, Yang L, Mueller M, Zhou XB, Dandolo L, Szendroedi J, Roden M, Flannery C, Taylor H, Carmichael GG, Shulman GI, Huang Y Nucleic acids research, 2014 (42), 13799 - 811 | | Submitted Externally | 25399420 | Published | |
| The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis.Wang GX, Zhao XY, Meng ZX, Kern M, Dietrich A, Chen Z, Cozacov Z, Zhou D, Okunade AL, Su X, Li S, Blüher M, Lin JD Nature medicine, 2014 (20), 1436 - 1443 | | Submitted Externally | 25401691 | Published | |
| Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling.Baeyens N, Mulligan-Kehoe MJ, Corti F, Simon DD, Ross TD, Rhodes JM, Wang TZ, Mejean CO, Simons M, Humphrey J, Schwartz MA Proceedings of the National Academy of Sciences of the United States of America, 2014 (111), 17308 - 13 | | Submitted Externally | 25404299 | Published | |
| Hypertension is associated with preamyloid oligomers in human atrium: a missing link in atrial pathophysiology?Sidorova TN, Mace LC, Wells KS, Yermalitskaya LV, Su PF, Shyr Y, Atkinson JB, Fogo AB, Prinsen JK, Byrne JG, Petracek MR, Greelish JP, Hoff SJ, Ball SK, Glabe CG, Brown NJ, Barnett JV, Murray KT Journal of the American Heart Association, 2014 (3), e001384 | | Submitted Externally | 25468655 | Published | |
| Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice.Fergusson G, Ethier M, Guévremont M, Chrétien C, Attané C, Joly E, Fioramonti X, Prentki M, Poitout V, Alquier T Molecular metabolism, 2014 (3), 848 - 854 | | Submitted Externally | 25506550 | Published | |
| Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance.Tsaousidou E, Paeger L, Belgardt BF, Pal M, Wunderlich CM, Brönneke H, Collienne U, Hampel B, Wunderlich FT, Schmidt-Supprian M, Kloppenburg P, Brüning JC Cell reports, 2014 (9), 1495 - 1506 | | Submitted Externally | 25456138 | Published | |
| Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas.Barnes TM, Otero YF, Elliott AD, Locke AD, Malabanan CM, Coldren AG, Brissova M, Piston DW, McGuinness OP American journal of physiology. Endocrinology and metabolism, 2014 (307), E896 - E905 | | | 25205821 | Published | |
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| Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection.Sandler NG, Zhang X, Bosch RJ, Funderburg NT, Choi AI, Robinson JK, Fine DM, Coombs RW, Jacobson JM, Landay AL, Douek DC, Tressler R, Read SW, Wilson CC, Deeks SG, Lederman MM, Gandhi RT, The Journal of infectious diseases, 2014 (210), 1549 - 54 | | Submitted Externally | 24864123 | Published | |
| Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog.Edgerton DS, Moore MC, Winnick JJ, Scott M, Farmer B, Naver H, Jeppesen CB, Madsen P, Kjeldsen TB, Nishimura E, Brand CL, Cherrington AD Diabetes, 2014 (63), 3946 - 3954 | | Submitted Externally | 24947349 | Published | |
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| Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice.Babaev VR, Hebron KE, Wiese CB, Toth CL, Ding L, Zhang Y, May JM, Fazio S, Vickers KC, Linton MF Journal of lipid research, 2014 (55), 2296 - 2308 | | Submitted Externally | 25240046 | Published | |
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| Synergistic simvastatin and metformin combination chemotherapy for osseous metastatic castration-resistant prostate cancer.Babcook MA, Shukla S, Fu P, Vazquez EJ, Puchowicz MA, Molter JP, Oak CZ, MacLennan GT, Flask CA, Lindner DJ, Parker Y, Daneshgari F, Gupta S Molecular cancer therapeutics, 2014 (13), 2288 - 2302 | | Submitted Externally | 25122066 | Published | |
| | | Submitted Externally | 25199945 | Published | |
| The PPARa-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway.Vernia S, Cavanagh-Kyros J, Garcia-Haro L, Sabio G, Barrett T, Jung DY, Kim JK, Xu J, Shulha HP, Garber M, Gao G, Davis RJ Cell Metabolism, 2014 (20), 512 - 525 | | | 25043817 | Published | |
| | | Submitted Externally | 24956127 | Published | |
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| Automated phenotyping and advanced data mining exemplified in rats transgenic for Huntington's disease.Urbach YK, Raber KA, Canneva F, Plank AC, Andreasson T, Ponten H, Kullingsjö J, Nguyen HP, Riess O, von Hörsten S Journal of neuroscience methods, 2014 (234), 38 - 53 | | Submitted Externally | 25020253 | Published | |
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| Inflammatory cytokines drive CD4+ T-cell cycling and impaired responsiveness to interleukin 7: implications for immune failure in HIV disease.Shive CL, Mudd JC, Funderburg NT, Sieg SF, Kyi B, Bazdar DA, Mangioni D, Gori A, Jacobson JM, Brooks AD, Hardacre J, Ammori J, Estes JD, Schacker TW, Rodriguez B, Lederman MM The Journal of infectious diseases, 2014 (210), 619 - 29 | | Submitted Externally | 24585897 | Published | |
| | | Submitted Externally | 24798517 | Published | |
| | | Submitted Externally | 24863362 | Published | |
| Renal blood flow and oxygenation drive nephron progenitor differentiation.Rymer C, Paredes J, Halt K, Schaefer C, Wiersch J, Zhang G, Potoka D, Vainio S, Gittes GK, Bates CM, Sims-Lucas S American journal of physiology. Renal physiology, 2014 (307), F337 - 45 | | Submitted Externally | 24920757 | Published | |
| I?B kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm.Stouch AN, Zaynagetdinov R, Barham WJ, Stinnett AM, Slaughter JC, Yull FE, Hoffman HM, Blackwell TS, Prince LS Journal of immunology (Baltimore, Md. : 1950), 2014 (193), 1184 - 93 | | Submitted Externally | 24981452 | Published | |
| Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.Mori MA, Thomou T, Boucher J, Lee KY, Lallukka S, Kim JK, Torriani M, Yki-Järvinen H, Grinspoon SK, Cypess AM, Kahn CR The Journal of clinical investigation, 2014 (124), 3339 - 3351 | | Submitted Externally | 24983316 | Published | |
| Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML International journal of radiation oncology, biology, physics, 2014 (89), 1106 - 1114 | | | 25035215 | Published | |
| | | Submitted Externally | 25158865 | Published | |
| Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, Lederman MM, Paiardini M, Kirchhoff F, Brenchley JM, Hunt PW, Silvestri G PLoS pathogens, 2014 (10), e1004345 | | Submitted Externally | 25167059 | Published | |
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| Hepatic glucose uptake and disposition during short-term high-fat vs. high-fructose feeding.Coate KC, Kraft G, Moore MC, Smith MS, Ramnanan C, Irimia JM, Roach PJ, Farmer B, Neal DW, Williams P, Cherrington AD American journal of physiology. Endocrinology and metabolism, 2014 (307), E151 - E160 | | Submitted Externally | 24865981 | Published | |
| | | Submitted Externally | 25001283 | Published | |
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| Quantitative Imaging of Preamyloid Oligomers, a Novel Structural Abnormality, in Human Atrial Samples.Sidorova TN, Mace LC, Wells KS, Yermalitskaya LV, Su PF, Shyr Y, Byrne JG, Petracek MR, Greelish JP, Hoff SJ, Ball SK, Glabe CG, Brown NJ, Barnett JV, Murray KT The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2014 (62), 479 - 87 | | Submitted Externally | 24789805 | Published | |
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| PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.Sajan MP, Ivey RA, Lee M, Mastorides S, Jurczak MJ, Samuels VT, Shulman GI, Braun U, Leitges M, Farese RV Molecular endocrinology (Baltimore, Md.), 2014 (28), 1097 - 107 | | Submitted Externally | 24877563 | Published | |
| Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia.Berglund ED, Liu T, Kong X, Sohn JW, Vong L, Deng Z, Lee CE, Lee S, Williams KW, Olson DP, Scherer PE, Lowell BB, Elmquist JK Nature neuroscience, 2014 (17), 911 - 913 | | Submitted Externally | 24908101 | Published | |
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| Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression.Sandler NG, Bosinger SE, Estes JD, Zhu RT, Tharp GK, Boritz E, Levin D, Wijeyesinghe S, Makamdop KN, del Prete GQ, Hill BJ, Timmer JK, Reiss E, Yarden G, Darko S, Contijoch E, Todd JP, Silvestri G, Nason M, Norgren RB, Keele BF, Rao S, Langer JA, Lifson JD, Schreiber G, Douek DC Nature, 2014 (511), 601 - 5 | | Submitted Externally | 25043006 | Published | |
| | | Submitted Externally | 25068089 | Published | |
| Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P Nature, 2014 (510), 547 - 551 | | Submitted Externally | 24870244 | Published | |
| Neu-Laxova syndrome, an inborn error of serine metabolism, is caused by mutations in PHGDH.Shaheen R, Rahbeeni Z, Alhashem A, Faqeih E, Zhao Q, Xiong Y, Almoisheer A, Al-Qattan SM, Almadani HA, Al-Onazi N, Al-Baqawi BS, Saleh MA, Alkuraya FS American journal of human genetics, 2014 (94), 898 - 904 | | Submitted Externally | 24836451 | Published | |
| RAGE regulates the metabolic and inflammatory response to high-fat feeding in mice.Song F, Hurtado del Pozo C, Rosario R, Zou YS, Ananthakrishnan R, Xu X, Patel PR, Benoit VM, Yan SF, Li H, Friedman RA, Kim JK, Ramasamy R, Ferrante AW, Schmidt AM Diabetes, 2014 (63), 1948 - 1965 | | | 24520121 | Published | |
| The MafA transcription factor becomes essential to islet ß-cells soon after birth.Hang Y, Yamamoto T, Benninger RK, Brissova M, Guo M, Bush W, Piston DW, Powers AC, Magnuson M, Thurmond DC, Stein R Diabetes, 2014 (63), 1994 - 2005 | | | 24520122 | Published | |
| | | Submitted Externally | 24571921 | Published | |
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| Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice.Lee EY, Kim YW, Oh H, Choi CS, Ahn JH, Lee BW, Kang ES, Cha BS, Lee HC Metabolism: clinical and experimental, 2014 (63), 793 - 799 | | Submitted Externally | 24684824 | Published | |
| Muscle-specific activation of Ca(2+)/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice.Lee HY, Gattu AK, Camporez JP, Kanda S, Guigni B, Kahn M, Zhang D, Galbo T, Birkenfeld AL, Jornayvaz FR, Jurczak MJ, Choi CS, Yan Z, Williams RS, Shulman GI, Samuel VT Diabetologia, 2014 (57), 1232 - 41 | | Submitted Externally | 24718953 | Published | |
| Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice.Fjære E, Aune UL, Røen K, Keenan AH, Ma T, Borkowski K, Kristensen DM, Novotny GW, Mandrup-Poulsen T, Hudson BD, Milligan G, Xi Y, Newman JW, Haj FG, Liaset B, Kristiansen K, Madsen L The Journal of biological chemistry, 2014 (289), 16032 - 45 | | Submitted Externally | 24742673 | Published | |
| Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI Nature, 2014 (510), 542 - 6 | | Submitted Externally | 24847880 | Published | |
| | | Submitted Externally | 24899308 | Published | |
| Effects of fish oil supplementation on prefrontal metabolite concentrations in adolescents with major depressive disorder: A preliminary (1)H MRS study.McNamara RK, Jandacek R, Rider T, Tso P, Chu WJ, Weber WA, Welge JA, Strawn JR, Adler CM, DelBello MP Nutritional neuroscience, 2014 | | Submitted Externally | 24915543 | Published | |
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| PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.Eren M, Boe AE, Murphy SB, Place AT, Nagpal V, Morales-Nebreda L, Urich D, Quaggin SE, Budinger GR, Mutlu GM, Miyata T, Vaughan DE Proceedings of the National Academy of Sciences of the United States of America, 2014 (111), 7090 - 5 | | Submitted Externally | 24778222 | Published | |
| IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice.Harley IT, Stankiewicz TE, Giles DA, Softic S, Flick LM, Cappelletti M, Sheridan R, Xanthakos SA, Steinbrecher KA, Sartor RB, Kohli R, Karp CL, Divanovic S Hepatology (Baltimore, Md.), 2014 (59), 1830 - 1839 | | | 24115079 | Published | |
| Associations of ghrelin with eating behaviors, stress, metabolic factors, and telomere length among overweight and obese women: preliminary evidence of attenuated ghrelin effects in obesity?Buss J, Havel PJ, Epel E, Lin J, Blackburn E, Daubenmier J Appetite, 2014 (76), 84 - 94 | | | 24462487 | Published | |
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| Early weight regain after gastric bypass does not affect insulin sensitivity but is associated with elevated ghrelin.Tamboli RA, Breitman I, Marks-Shulman PA, Jabbour K, Melvin W, Williams B, Clements RH, Feurer ID, Abumrad NN Obesity (Silver Spring, Md.), 2014 (22), 1617 - 1622 | | Submitted Externally | 24777992 | Published | |
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