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Experiment

Metabolic Clamp Study in MT2 KO Mice
Summary Data Summary
Investigator Baba, Kenkichi
Description MT2 KO mice: Although circadian functions were normal, the phase shifting effect
of melatonin on suprachiasma neuronal firing rhythms was abolished,
Photo-insensitivity in retina

This follow-up study is approved for the Metabolism Core of UMass MMPC and will
involve 8 MT2 KO mice for body composition and hyperinsulinemic-euglycemic clamp
study. This study will be led by Dr. Hye-Lim Noh and will be scheduled for
mid-July shipping for clamp studies to be scheduled at the end of August.

Applicable research area(s): Diabetes, Obesity, Metabolism, Neurobiology
Status PhenStat Analysis Verified
Public Release 12/11/2017
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals12
Experimental Conditions1
Catalog Items3
Curation Info (# flags)1
Phenotype Assays14
Phenotype Measurements168
Histology Images0
Publications0
Phenotypes7


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
5
0
129S7/SvEvBrd-Mt1tm1Bri Mt2tm1Bri
0
7
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor (Units)
Experimental Group
Experimental Factor Values


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