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Experiment

Metabolic Clamp Study in MT2 KO Mice
Summary Data Summary
Investigator Baba, Kenkichi
Description MT2 KO mice: Although circadian functions were normal, the phase shifting effect
of melatonin on suprachiasma neuronal firing rhythms was abolished,
Photo-insensitivity in retina

This follow-up study is approved for the Metabolism Core of UMass MMPC and will
involve 8 MT2 KO mice for body composition and hyperinsulinemic-euglycemic clamp
study. This study will be led by Dr. Hye-Lim Noh and will be scheduled for
mid-July shipping for clamp studies to be scheduled at the end of August.

Applicable research area(s): Diabetes, Obesity, Metabolism, Neurobiology
Status Completed
Public Release 12/11/2017
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals12
Experimental Conditions1
Catalog Items3
Curation Info (# flags)1
Phenotype Assays14
Phenotype Measurements168
Histology Images0
Publications0
Phenotypes7


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
5
0
129S7/SvEvBrd-Mt1tm1Bri Mt2tm1Bri
0
7
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.



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