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Experiment

Comprehensive Metabolic Study in HFD-fed MCK-Pike KO Mice
Summary Data Summary
Investigator Chan, Chi
Description The MPKO mice represent a new model for studying the obesity-induced metabolic
changes. The MPKO mice develop less diet-induced obesity and insulin resistance.

This study is approved for the Metabolism Core of UMass MMPC and will involve 16
HFD-fed mice (8 WT and 8 MCK-Pike KO mice) for body composition, metabolic cage
analysis, and hyperinsulinemic-euglycemic clamp experiments. This study will be
led by Dr. Taekyoon Kim and Dr. Hee Joon Kang.

Applicable research area(s): Diabetes, Obesity, Metabolism
Status Completed
Public Release 12/11/2017
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals16
Experimental Conditions1
Catalog Items5
Curation Info (# flags)1
Phenotype Assays19
Phenotype Measurements304
Histology Images0
Publications0
Phenotypes5


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
8
0
0
Muscle-specific Pike KO
8
0
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.



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