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Experiment

Imeglimin CLAMS
Summary Data Summary
Investigator Shulman, Gerald I.
Description Evaluating the impact of imeglimin on energetics, food intake, and body
composition.

Applicable research area(s): Diabetes, Obesity, Metabolism
Status Completed
Public Release 7/13/2018
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals32
Experimental Conditions4
Catalog Items1
Curation Info (# flags)2
Phenotype Assays11
Phenotype Measurements528
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
32
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Imeglimin
Imeglimin is an experimental drug being developed as an oral anti-diabetic. It is an oxidative phosphorylation blocker that acts to inhibit hepatic gluconeogenesis, increase muscle glucose uptake, and restore normal insulin secretion.
 No Drug/Treatment
No Drug or Treatment done on these samples

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Research Diets - D12492
Rodent Diet with 34% Fat, 60% kcal from Fat
 Teklad - 2018
2018 Teklad Global 18% Protein Rodent Diet is a fixed formula, non-autoclavable diet manufactured with high quality ingredients and designed to support gestation, lactation, and growth of rodents. 2018 does not contain alfalfa, thus lowering the...
Experimental Factor Values


No documents found.

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