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Experiment

Sable Energy Balance #22417 8/7/17

Summary

Data Summary

Investigator	Chen, Xin Jie
Description	Energy expenditure measured by indirect calorimetry in the Promethion by Sable Systems. Activity, food intake and water intake are also continuously measured. Measurements were taken for 5 consecutive days. Running wheels were not present in the cage. Mice were fed ad libitum. The Tg/+ mice are marked as ND(Procedure not done) because they had to be hand fed, in addition to using the Promethion food hoppers. The WT mice used only the Promethion food hoppers. Water: regular tap water, ad libitum. Groups: Male and Female WT(C57BL/6) and mice Tg/+ (C57BL/6-Tg(Slc25a4-Slc25a4)1Chen). Mice were fed a chow diet (LabDiet 5008). Applicable research area(s): Cardiovascular, Metabolism
Status	Completed
Public Release	11/8/2020
Animal Age	Measured In: day(s) post-natal (d)
Flags

Data Analysis

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Type	Count
Animals	16
Experimental Conditions	2
Catalog Items	7
Curation Info (# flags)	0
Phenotype Assays	14
Phenotype Measurements	224
Histology Images	0
Publications	0
Phenotypes	6

Animals

Strain Name	Common Name	Females	Males	Unknown
C57BL/6	C57BL/6	4	4	0
C57BL/6-Tg(Slc25a4-Slc25a4)1Chen	C57BL/6-Tg(Slc25a4-Slc25a4)1Chen	4	4	0

Animals/Strains

Experimental Factors

	Categorical Values
	Name / Abbreviation	Description
	Experimental Factor: Experimental Group
	Control	This animal belongs to the control group for the experiment.
	Experiment	This animal belongs to experimental group that is homozygous for gene manipulations.
	Experimental Factor: Mouse Diet
	LabDiet 5008	crude protein (23.0%), crude fat (6.5%), crude fiber (4.0%), Ash (< 8.0%), minerals (2.5%)

Experimental Factor (Units)
Experimental Group
Mouse Diet

Experimental Factor Values

Phenotype Assays Add / Edit

Name	Abbreviation
body mass	W rodent
oxygen consumption (Light Period)	VO2-L
fat body mass	fat body mass
lean body mass	lean body mass
respiratory exchange ratio (Light Period)	RER-L
body water, free	free water
heat (Light Period)	HEAT-Light
oxygen consumption (Dark Period)	VO2-D
carbon dioxide production Light Period	VCO2-L
carbon dioxide production Dark Period	VCO2-D
respiratory exchange ratio (Dark Period)	RER-D
heat (Dark Period)	HEAT-Dark
temperature, environmental	ENV TEMP
food intake	food intake

No documents found.

Mammalian Phenotype (MP) Terms

MPTermID	MPTermName	Definition	Other Results
MP:0000683	decreased percent water in carcass	less than the normal total amount of water retained in the body measured post mortem [MGI:il]	MMPC Search Results
MP:0001262	decreased body weight	lower than normal average weight [PMID:10709991]	MMPC Search Results
MP:0003961	decreased lean body mass	reduced amount of the fat-free physical bulk or volume of the body including all its components except adipose (fat) tissue [MGI:csmith]	MMPC Search Results
MP:0005290	decreased oxygen consumption	less than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body [MESH:G06.535.723]	MMPC Search Results
MP:0008964	decreased carbon dioxide production	reduction in the rate at which carbon dioxide leaves the blood and enters the alveolar gas [MGI:csmith]	MMPC Search Results
MP:0010378	increased respiratory quotient	increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls [MGI:csmith]	MMPC Search Results

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