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Hyperinsulinemic Euglycemic clamp order # 22422 Dec 2017
Summary Data Summary
Investigator Ha, Arnold
Description C57BL/6J mice can be a representative model for multiple human conditions and
are used throughout research as such a model. The antibody was administered
intraperitoneally 1 hour before insulin treatment. The ALULA antibody affects
insulin sensitivity.

Applicable research area(s): Diabetes, Metabolism
Status Completed
Public Release 6/21/2020
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
Experimental Conditions8
Catalog Items4
Curation Info (# flags)1
Phenotype Assays18
Phenotype Measurements5377
Histology Images0

Strain NameCommon NameFemalesMalesUnknown

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 2H6-2C IGg2B
control antibody (for comparison to ALULA); stock concentration 2.2 mg/ml
IgG2b isotype mouse monoclonal antibody against avß5; stock concentration 1.9 mg/ml

Experimental Factor: Drug Dose (AU)

 Drug Dose
A numerical value indicating the dose of a drug administered. The unit of measure is indicated in the Drug Dose Units categorical value that accompanies this experimental condition.

Experimental Factor: Drug Dose Units

milligrams per milliliter

Experimental Factor: Experimental Group

This animal belongs to the control group for the experiment.
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Glucose Infusion Rate (mg/kg/min)

 Glucose Infusion Rat
Rate of glucose infusion for clamp experiments

Experimental Factor: Insulin Infusion Rate - milliUnits (mU/kg/min)

 Insulin Infusion Rat
This is insulin infusion rate for hyperinsulinemic clamp data

Experimental Factor: Mouse Diet

 LabDiet PicoLab Rodent Diet 5LOD
Crude Protein 23%, crude fat 4.5%, crude fiber 6.0%. Ingredients: dehulled soybean meal, ground corn, dried beet pulp, fish meal, ground oats, dehydrated alfalfa meal, cane molasses, brewers dried yeast, wheat germ, whey, porcine animal fat...

Experimental Factor: Time Sample Taken (min)

 Time Sample Taken
Time in minutes since a sample was taken

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