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Experiment

Circulating corticosterone levels in liver specific Klf15 KO mice treated with
LPS Part 2
Summary Data Summary
Investigator Srivastava, Deepak
Description Administered dose of LPS is 15ug/g body weight. The hypothesis is that control
mice will respond to LPS in terms of higher CORT, while KO mice will have less
response to LPS, which means a smaller increase in CORT.
Status Completed
Public Release 3/22/2021
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals29
Experimental Conditions9
Catalog Items1
Curation Info (# flags)1
Phenotype Assays1
Phenotype Measurements29
Histology Images0
Publications0
Phenotypes2


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J +/+
0
16
0
Klf15 Liver KO
0
13
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 LPS
Lipopolysaccharide - induces bacterial infection
 Vehicle
Vehicle - Control

Experimental Factor: Drug Delivery Route

 IP
The drug was delivered intraperitoneal.

Experimental Factor: Drug Dose Units

 mg/kg once
milligrams per kilogram one dose

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Feeding Group

 Fed
Animals are allowed to have food.

Experimental Factor: Mouse Diet

 LabDiet 5001
crude protein (23.0%), crude fat (4.5%), crude fiber (6.0%), Ash (< 8.0%), minerals (2.5%)

Experimental Factor: Tissue Source

 plasma (EDTA)
plasma (EDTA)
Experimental Factor Values


Phenotype Assays Add / Edit


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