mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Experiment

2021-08-08 Olson - Ian 14 Mice 5 Day CLAMS with 2 Injections & fasting
Summary Data Summary
Investigator Olson, David
Description We injected a 4Di virus into the PVH of NOS1-Cre mice to inhibit their activity.
The mice were separated into 2 groups, one that receives CNO for the first
injection day and then Saline for the second injection day, and one group that
receives Saline on the first injection day and then CNO on the second. Both days
mice were fasted from 9am and refed at 5pm.
Status Completed
Public Release 1/5/2024
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagExperiment / ControlMetadataNo Experimental GroupNeed ConditionsNomenclature
Data Analysis
TypeCount
Animals14
Experimental Conditions5
Catalog Items1
Curation Info (# flags)5
Phenotype Assays9
Phenotype Measurements44856
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
B6.129-Nos1tm1(cre)Mgmj/J
0
14
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Clozapine N-oxide
Inactive from of clozapine drug, activates G-protein-coupled receptors (GPCRs). CNO serves as a synthetic ligand for engineered human muscarinic receptor. It elicits clozapine-like effects upon metabolic conversion. Clozapine conversion to CNO favors its
 Saline
Saline

Experimental Factor: Experimental Group

 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 LabDiet PicoLab Rodent Diet 5LOD
Crude Protein 23%, crude fat 4.5%, crude fiber 6.0%. Ingredients: dehulled soybean meal, ground corn, dried beet pulp, fish meal, ground oats, dehydrated alfalfa meal, cane molasses, brewers dried yeast, wheat germ, whey, porcine animal fat...

Experimental Factor: Second Drug Administered

 Clozapine N-oxide
The second drug that was administered during the study.
 Saline
The second drug that was administered during the study.
Experimental Factor Values


No documents found.

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.