mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Experiment

2021-08-01 Olson - Ian 14 Mice 5 Day CLAMS with 2 Injections and fasting
Summary Data Summary
Investigator Olson, David
Description We injected NOS1-Cre mice with 4Di to investigate acute and chronic inhibition
of NOS1 neurons in the PVH. Mice are organized into two groups, those who
received the CNO injection on day 1 during fasting and then the Saline injection
on day 2 during fasting and those who received Saline on day 1 and then CNO
injection on day 2.
Status Completed
Public Release 1/6/2024
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagExperiment / ControlMetadataNo Experimental GroupNeed ConditionsNomenclature
Data Analysis
TypeCount
Animals14
Experimental Conditions5
Catalog Items1
Curation Info (# flags)5
Phenotype Assays2
Phenotype Measurements9968
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
B6.129-Nos1tm1(cre)Mgmj/J
14
0
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Clozapine N-oxide
Inactive from of clozapine drug, activates G-protein-coupled receptors (GPCRs). CNO serves as a synthetic ligand for engineered human muscarinic receptor. It elicits clozapine-like effects upon metabolic conversion. Clozapine conversion to CNO favors its
 Saline
Saline

Experimental Factor: Experimental Group

 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 LabDiet PicoLab Rodent Diet 5LOD
Crude Protein 23%, crude fat 4.5%, crude fiber 6.0%. Ingredients: dehulled soybean meal, ground corn, dried beet pulp, fish meal, ground oats, dehydrated alfalfa meal, cane molasses, brewers dried yeast, wheat germ, whey, porcine animal fat...

Experimental Factor: Second Drug Administered

 Clozapine N-oxide
The second drug that was administered during the study.
 Saline
The second drug that was administered during the study.
Experimental Factor Values


Phenotype Assays Add / Edit


No documents found.

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.