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Experiment

2020-11-08 Olson - Ian CNO CLAMS 11 mice
Summary Data Summary
Investigator Olson, David
Description L10-GFP and WT mice were injected with a Retro-Cre virus into the NTS and
injected with a Cre dependent 3Dq virus in the PVH to assess manipulation of PVH
-> NTS projecting neurons.
Status Completed
Public Release 1/27/2024
Animal Age Measured In: month(s) post-natal (m)
Flags has-data-flagExperiment / Control
Data Analysis
TypeCount
Animals11
Experimental Conditions3
Catalog Items1
Curation Info (# flags)1
Phenotype Assays6
Phenotype Measurements23496
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
B6.129-Nos1tm1(cre)Mgmj/J
0
11
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 Clozapine N-oxide
Inactive from of clozapine drug, activates G-protein-coupled receptors (GPCRs). CNO serves as a synthetic ligand for engineered human muscarinic receptor. It elicits clozapine-like effects upon metabolic conversion. Clozapine conversion to CNO favors its

Experimental Factor: Experimental Group

 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor Values


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