mmpc-logo mmpc-logo
twitter-logo @NationalMMPC
| Create Account | login
Experiment

2020-09-21 Rui - Yuan 10 Mice 3 Day CLAMS Run
Summary Data Summary
Investigator Li, Yuan
Description Our studies will define a molecule called YTHDC1 as a critical regulator in body
weight and metabolism, and a potential target for the intervention of obesity
and its associated cardiovascular disease.
In the preliminary study, I found that hypothalamic Ythdc1 is markedly
downregulated in obesity, suggesting that hypothalamic Ythdc1 deficiency
contributes to obesity development. Strikingly, I further observed that POMC
neuron-specific deletion of Ythdc1 (PKO) results in severe obesity, liver
steatosis, and insulin resistance
Status Completed
Public Release 2/2/2024
Animal Age Measured In: week(s) post-natal (w)
Flags
Data Analysis
TypeCount
Animals10
Experimental Conditions3
Catalog Items2
Curation Info (# flags)4
Phenotype Assays2
Phenotype Measurements0
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
8
0
Unknown
0
2
0

Animals/Strains
Experimental Factors
Experimental Factor Values


Phenotype Assays Add / Edit


No documents found.

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.