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Experiment

LETMD ß- adrenergic agonist high-resolution CLAMS
Summary Data Summary
Investigator Yoon, John
Description This study will determine how b-agonist alters energy expenditure in LETMD1 KO
male mice. WT and LETMD mice will underwent baseline calorimetry assessment
prior to being exposed to Vehicle (saline and DMSO) and ß-adrenergic agonist
while undergoing high resolution indirect calorimetry.
Status Completed
Public Release 4/20/2024
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals13
Experimental Conditions7
Catalog Items4
Curation Info (# flags)1
Phenotype Assays1
Phenotype Measurements858
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6N +/+
0
6
0
C57BL/6J-Letmd1em1Jcy
0
7
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Drug Administered

 CL 316,243
A highly selective ß3 adrenoceptor agonist that has been shown to cause increases in brown adipose tissue thermogenesis and metabolic rate as well as decreases in blood insulin and glucose levels.
 Saline
Saline

Experimental Factor: Drug Delivery Route

 IP
The drug was delivered intraperitoneal.

Experimental Factor: Drug Dose Units

 mg/kg
milligrams per kilogram

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor Values


Phenotype Assays Add / Edit


No documents found.

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