mmpc-logo mmpc-logo
twitter-logo    bluesky-logo
| Create Account | login
Experiment

LetMD cold challenge CLAMS
Summary Data Summary
Investigator Yoon, John
Description This study will determine whether LETMD1 KO alters energy expenditure during a
3-week cold challenge. WT and LETMD mice will be exposed to either room temp
(~22°C) or cold challenge (10°C) for three weeks prior to undergoing indirect
calorimetry followed by body composition analysis by Echo-MRI. The first 2 weeks
they will be exposed to cold at investigators vivarium and the last ~ week at
MBP.
Status PhenStat Analysis Verified
Public Release 4/20/2024
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flag
Data Analysis
TypeCount
Animals10
Experimental Conditions3
Catalog Items3
Curation Info (# flags)0
Phenotype Assays27
Phenotype Measurements270
Histology Images0
Publications0
Phenotypes14


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6N +/+
0
4
0
C57BL/6J-Letmd1em1Jcy
0
6
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Teklad - 2918
Harlan-Teklad 2918 (Irradiated) 18.6% protein (Calories : 24% protein, 18% Fat, 58% Carbohydrate) Ingredients—Ground wheat, ground corn, wheat middlings, dehulled soybean meal, corn gluten meal, soybean oil, calcium carbonate, brewers dried yeast,...
Experimental Factor Values


No documents found.


Mammalian Phenotype (MP) Terms
MPTermIDMPTermNameDefinitionOther Results
MP:0001402decreased locomotor activity
general reduction in locomotor activity; reduced movement from one place to another [ISBN:0-683-40008-8| MGI:csmith]
MMPC Search Results
MP:0003961decreased lean body mass
reduced amount of the fat-free physical bulk or volume of the body including all its components except adipose (fat) tissue [MGI:csmith]
MMPC Search Results
MP:0005202lethargy
mild impairment of consciousness resulting in reduced alertness and awareness and/or sluggish behavior or inactivity; can be due to generalized brain dysfunction [ISBN:0-683-40008-8]
MMPC Search Results
MP:0005290decreased oxygen consumption
less than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body [MESH:G06.535.723]
MMPC Search Results
MP:0005458increased percent body fat/body weight
more fat| relative to controls| expressed as a percentage of total body weight [MGI:cwg]
MMPC Search Results
MP:0008964decreased carbon dioxide production
reduction in the rate at which carbon dioxide leaves the blood and enters the alveolar gas [MGI:csmith]
MMPC Search Results
MP:0010024increased total body fat amount
greater than the normal total amount of connective tissue composed of fat cells within the entire body [MGI:csmith]
MMPC Search Results
MP:0010378increased respiratory quotient
increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls [MGI:csmith]
MMPC Search Results
MP:0010379decreased respiratory quotient
reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls [MGI:csmith]
MMPC Search Results
MP:0011940decreased food intake
reduction in the total number of calories or food amount taken in over time when compared to the normal state [MGI:csmith]
MMPC Search Results
MP:0011946decreased eating frequency
reduction in the number of discrete instances of initiation of eating over time| regardless of amount eaten [MGI:csmith]
MMPC Search Results
MP:0012344decreased gnawing activity
decreased biting or chewing on something [https://orcid.org/0000-0001-5208-3432]
MMPC Search Results
MP:0014142increased body fat mass
increased physical bulk or volume of fat in the whole body [MGI:csmith]
MMPC Search Results
MP:0020211slow movement
decreased rate or speed of the coordinated movements executed with a purpose [https://orcid.org/0000-0001-5208-3432]
MMPC Search Results

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.