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Experiment

2018-09-07 Olson - Latrice 29 Mice NMR
Summary Data Summary
Investigator Olson, David
Description The PVH is a heterogeneous nucleus composed of multiple cell types expressing a
variety of neuropeptides. We recently showed that PVH neurons expressing nitric
oxide synthase-1 (NOS1) represent a subset of PVH neurons and that their
activation suppresses food intake and increases energy expenditure. Thus we
hypothesize that PVHNOS1 neurons represent a complimentary, non-melanocortin
target for anti-obesity therapies.
Status Completed
Public Release 5/12/2024
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainNeed Conditions
Data Analysis
TypeCount
Animals29
Experimental Conditions4
Catalog Items1
Curation Info (# flags)2
Phenotype Assays6
Phenotype Measurements348
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
B6.129-Nos1tm1(cre)Mgmj/J
19
10
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 LabDiet PicoLab Rodent Diet 5LOD
Crude Protein 23%, crude fat 4.5%, crude fiber 6.0%. Ingredients: dehulled soybean meal, ground corn, dried beet pulp, fish meal, ground oats, dehydrated alfalfa meal, cane molasses, brewers dried yeast, wheat germ, whey, porcine animal fat...

Experimental Factor: Strain Type

 Heterozygous
Having two different alleles of a particular gene or genes
 Homozygous
Having two identical alleles of a particular gene or genes.
Experimental Factor Values


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