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Experiment

Metabolic Study in ACAT1 Mice
Summary Data Summary
Investigator Chang, Ta-Yuan
Description This strain is valuable for obesity, type II diabetes, and atherosclerosis
research.

The macrophage specific Acat1-/- mice are resistant to diet induced weight gain.
With Western diet, they have lower insulin level as well as lower glucose level.
They are more sensitive to glucose tolerance test than the WT mice.

Applicable research area(s): Diabetes, Obesity, Metabolism, Cardiovascular
Status Completed
Public Release 9/30/2015
Animal Age Measured In: month(s) post-natal (m)
Flags has-data-flagSame StrainExperiment Description
Data Analysis
TypeCount
Animals20
Experimental Conditions1
Catalog Items4
Curation Info (# flags)2
Phenotype Assays15
Phenotype Measurements300
Histology Images0
Publications0
Phenotypes2


Animals

Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
10
0
Acat1 KO
0
10
0


Experimental Factors
 Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.



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