mmpc-logo mmpc-logo
twitter-logo @NationalMMPC
| Create Account | login
Experiment

Comprehensive Metabolic and Analytical Study in Lyz-Acat1-ApoE Double KO Mice
Summary Data Summary
Investigator Chang, Ta-Yuan
Description To test the effect of macrophage- specific Acat1 Ko on apoe KO mouse for
atherosclerosis. To test the hypothesis that Acat1 in macrophage as a
therapeutic target for treating atherosclerosis.

Acat1 in macrophage decreases atherosclerostic lesions, decreases steady state
glucose level, reduces leptin level in the blood, and increases insulin
sensitivity.

Applicable research area(s): Diabetes, Obesity, Metabolism, Cardiovascular
Status Completed
Public Release 9/24/2016
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame Strain
Data Analysis
TypeCount
Animals12
Experimental Conditions1
Catalog Items11
Curation Info (# flags)1
Phenotype Assays20
Phenotype Measurements276
Histology Images0
Publications0
Phenotypes2


Animals
Strain NameCommon NameFemalesMalesUnknown
Apoe-/- Acat1-M/-M
0
6
0
Acat1 KO
0
6
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.
Experimental Factor (Units)
Experimental Group


No documents found.

Menu

Home
Contact
About MMPC
Animal Husbandry
Tests Data
Search Data
Analysis
Clients
MMPC Centers

Newsletter

Interested in receiving MMPC News?
twitter-logo Mouse Phenotyping
@NationalMMPC



2017 National MMPC. All Rights Reserved.