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Strain
C57BL/6-Cenpftm1Dbdr Tg(Tnnt2-cre)5Blh

Summary Data Summary
Official Name C57BL/6-Cenpftm1Dbdr Tg(Tnnt2-cre)5Blh
Common Name C57BL/6-Cenpftm1Dbdr Tg(Tnnt2-cre)5Blh
Description CENPF-loxP/loxP mouse was crossed with cTNT-Cre mouse to
target CENPF deletion specifically in cardiomyocytes

Cenpf knockin: Two loxP sites were inserted flanking exons 1
to 5 of Cenpf. The floxed region contains functional binding
domains for synthaxin 4, Hook2, and Snap25.
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Experiments 1
Publications 1


Investigators
NameInstitution
David BaderVanderbilt University


Genomic Information
GeneAllele 1Allele 2Protocol
Cenpfknockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedTnnt2CRENot Specified






PublicationAltmetricsSubmitted ByPubMed IDStatus
Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy.
Dees E, Miller PM, Moynihan KL, Pooley RD, Hunt RP, Galindo CL, Rottman JN, Bader DM
Disease models & mechanisms, 2012 (5), 468 - 480
22563055
Published

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