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Strain
B6.129S6-Ptger4tm1.2Matb

Summary Data Summary
Official Name B6.129S6-Ptger4tm1.2Matb
Common Name C57BL/6J-Ptger4+/-
Description Deletion of exon 2 was accomplished by taking single cell
embryos carrrying an allele containing loxP sites that flank
exon 2 and injecting a cre-expression plasmid. Mice were
produced from the embryos that carried the deleted allele.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1
Publications 1


Investigators
NameInstitution
Matthew BreyerEli Lilly and Company


Genomic Information
GeneAllele 1Allele 2Protocol
Ptger4knockoutwildNot Specified






PublicationAltmetricsSubmitted ByPubMed IDStatus
Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis.
Babaev VR, Chew JD, Ding L, Davis S, Breyer MD, Breyer RM, Oates JA, Fazio S, Linton MF
Cell Metabolism, 2008 (8(6)), 492 - 501
Submitted Externally
19041765
Published

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