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Strain
C57BL/6J-Slc2a4tm1Mch Tg(Hk2)

Summary Data Summary
Official Name C57BL/6J-Slc2a4tm1Mch Tg(Hk2)
Common Name C57BL/6J-Slc2a4-/- Tg(Hk2)
Description A neomycin resistance cassette was inserted into exon 10 of
the Slc2a4 gene, disrupting expression. Loss of expression
was shown by Northern and Western blots of skeletal muscle.

Mice over-express Hk2
Development Status Phenotyping ongoing
Creation Method transgenic
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Publications 3


Investigators
NameInstitution
David WassermanVanderbilt University


Genomic Information
GeneAllele 1Allele 2Protocol
Slc2a4knockoutknockoutNot Specified
EnhancerPromoterGeneCopies
Not SpecifiedNot SpecifiedHk2Not Specified




PublicationAltmetricsSubmitted ByPubMed IDStatus
Regulation of insulin-stimulated muscle glucose uptake in the conscious mouse: role of glucose transport is dependent on glucose phosphorylation capacity.
Fueger PT, Hess HS, Bracy DP, Pencek RR, Posey KA, Charron MJ, Wasserman DH
Endocrinology, 2004 (145), 4912 - 4916
15284204
Published
Control of exercise-stimulated muscle glucose uptake by GLUT4 is dependent on glucose phosphorylation capacity in the conscious mouse.
Fueger PT, Hess HS, Posey KA, Bracy DP, Pencek RR, Charron MJ, Wasserman DH
The Journal of biological chemistry, 2004 (279), 50956 - 50961
15456776
Published
Glucose kinetics and exercise tolerance in mice lacking the GLUT4 glucose transporter.
Fueger PT, Li CY, Ayala JE, Shearer J, Bracy DP, Charron MJ, Rottman JN, Wasserman DH
The Journal of physiology, 2007 (582), 801 - 812
17495042
Published

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