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Strain
B6.129X1-Nfe2l2tm1Ywk/J

Summary Data Summary
Official Name B6.129X1-Nfe2l2tm1Ywk/J
Common Name Nrf2 KO
Description A 4.2 kb segment, includind part of exon 4 and all of exon
5, was replaced by an in-frame lacZ gene followed by a
neomycin selection cassette. Northern blot analysis on RNA
derived from various tissues confirmed that a fusion
transcript was detectable in intestine of homozygous mice,
but no wild-type transcript was detectable in any tissue.
However, no fusion protein was detected by histochemical
staining in any adult tissue.
Development Status Phenotyping ongoing
Creation Method knockout
Breeding Type backcross
Breeding Generations 9
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 2


Investigators
NameInstitution
Michael FreemanVanderbilt University


Genomic Information
GeneAllele 1Allele 2Protocol
Nfe2l2knockoutknockoutNot Specified


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