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Strain
C57BLKS-Relatm1Jpy Tg(Lyz2-Cre)

Summary Data Summary
Official Name C57BLKS-Relatm1Jpy Tg(Lyz2-Cre)
Common Name C57BLKS-Relalox/lox Tg(Lys-CRE)
Description A loxP site was inserted upstream of exon 2 and a floxed neo
cassette was inserted downstream of exon 4 via homologous
recombination.
Development Status Phenotyping ongoing
Creation Method transgenic
Background C57BLKS/J
Phenotype Description This model is made to understand chronic inflammation in the
pathogenesis of insulin resistance of obese subjects.
Inflammation with improved insulin sensitivity in obese
condition.
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Experiments 1
Publications 1


Investigators
NameInstitution
Jianping YeLouisiana Technical College-Baton Rouge Campus


Genomic Information
GeneAllele 1Allele 2Protocol
Relaknockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedLyz2CRENot Specified






PublicationAltmetricsSubmitted ByPubMed IDStatus
P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice.
Gao Z, Zhang J, Henagan TM, Lee JH, Ye X, Wang H, Ye J
American journal of physiology. Endocrinology and metabolism, 2015 (308), E496 - 505
Submitted Externally
25564477
Published

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