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Strain
C57BL/6-Mc4rtm1Dhu

Summary Data Summary
Official Name C57BL/6-Mc4rtm1Dhu
Common Name C57BL/6-Mc4r-/-
Description melanocortin 4 receptor (Mc4r) homozygous knockout on the
C57BL/6 background.
Development Status Phenotyping ongoing
Creation Method knockout
Background C57BL/6
Breeding Type backcross
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 5
Publications 2


Investigators
NameInstitution
Roger ConeOregon Health Sciences University


Genomic Information
GeneAllele 1Allele 2Protocol
Mc4rknockoutknockoutNot Specified






PublicationAltmetricsSubmitted ByPubMed IDStatus
Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods.
Panaro BL, Cone RD
Proceedings of the National Academy of Sciences of the United States of America, 2013 (110), 7050 - 5
Submitted Externally
23569235
Published
Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy.
Litt MJ, Okoye GD, Lark D, Cakir I, Moore C, Barber MC, Atkinson J, Fessel J, Moslehi J, Cone RD
eLife, 2017 (6)
Submitted Externally
28829041
Published

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