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Strain
B6;129S6-Rr35tm1.1Lap

Summary Data Summary
Official Name B6;129S6-Rr35tm1.1Lap
Common Name B6;129S6-mm771tm1.1Lap
Description The noncoding transcriptional enhancer sequence (Rr35 or
mm771) was replaced with a floxed neo selection cassette,
which was subsequently removed by cre excision.

The construct was electroporated into 129S6/SvEvTac-derived
W4 embryonic stem (ES) cells. Correctly targeted ES cells
were injected into recipient blastocysts. The resulting
chimeric animals were crossed to C57BL/6 mice for
approximately five generations.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Experiments 2
Publications 1


Investigators
NameInstitution
Diane DickelLawrence Berkeley National Laboratory






PublicationAltmetricsSubmitted ByPubMed IDStatus
Genome-wide compendium and functional assessment of in vivo heart enhancers.
Dickel DE, Barozzi I, Zhu Y, Fukuda-Yuzawa Y, Osterwalder M, Mannion BJ, May D, Spurrell CH, Plajzer-Frick I, Pickle CS, Lee E, Garvin TH, Kato M, Akiyama JA, Afzal V, Lee AY, Gorkin DU, Ren B, Rubin EM, Visel A, Pennacchio LA
Nature communications, 2016 (7), 12923
Submitted Externally
27703156
Published

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