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Strain
C57BL/6-Nrg4tm1Lin

Summary Data Summary
Official Name C57BL/6-Nrg4tm1Lin
Common Name neuregulin 4
Description The transgenic vector was constructed by placing mouse Nrg4
cDNA that contains part of 5' and 3' UTR between the aP2
enhancer/promoter sequence and human growth hormone
polyadenylation signal. Mouse Nrg4 cDNA (including 5'UTR and
partial 3'UTR) were TA-cloned into pCR2.1 TOPO vector. The
transgenic vector was linearized by using HindIII and ApaI
to release the transgenic cassette for microinjecting into
fertilized eggs from C57BL/6J mice. Transgenic mice were
generated at the Transgenic Animal Model Core at the
University of Michigan.
Development Status Phenotyping ongoing
Creation Method transgenic
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Jiandie LinUniversity of Michigan


Genomic Information
GeneAllele 1Allele 2Protocol
Nrg4transgenictransgenicNot Specified


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