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Strain
NMRI-Prox1tm1Gco/+

Summary Data Summary
Official Name NMRI-Prox1tm1Gco/+
Common Name NMRI-Prox1tm1Gco/+
Description The NMRI outbred model was developed by Lynch et al. Poiley
of the National Institutes of Health received stock from
Lynch in 1937. The mice were inbred as NIH/P1. The Naval
Medical Research Institute (NMRI) received stock from Lynch.
Zentralinstitut für Versuchstierzucht in Hannover Germany
(Han) received stock from NMRI. The mice were random bred.
M&B A/S (now Taconic Europe) received stock from Han in 1961
and again in 1985. The mice are maintained as an outbred
stock.

A cassette containing lacZ and neo was fused in frame at the
codon 224. Expression of beta-galactosidase was driven by
the endogenous promoter. These are heterozygous wildtype
mice.
Development Status Phenotyping ongoing
Creation Method knockout
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Guillermo OliverSt. Jude Childrens Research Hospital


Genomic Information
GeneAllele 1Allele 2Protocol
Prox1knockoutwildNot Specified


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