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Strain
B6.129-Prkaa1tm1.1Mfor Prkaa2tm1Vio

Summary Data Summary
Official Name B6.129-Prkaa1tm1.1Mfor Prkaa2tm1Vio
Common Name B6.129-Prkaa1tm1.1Mfor Prkaa2tm1Vio
Description Protein kinase, AMP-activated, alpha 1 catalytic subunit
(Prkaa1) and protein kinase, AMP-activated, alpha 2
catalytic subunit (Prkaa2) genes were floxed alleles.

Prkaa1: An FRT-flanked hygromycin cassette with a 3' loxP
site was inserted downstream of exon 5, and an additional
loxP site was inserted upstream of exon 4. Flp-mediated
recombination removed the hygromycin cassette.

Prkaa2: The exon encoding amino acids 189 through 260 was
flanked by an upstream single loxP site and a downstream
floxed neo cassette.
Development Status Phenotyping ongoing
Creation Method knockin
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Modifications 2
Experiments 1
Publications 1


Investigators
NameInstitution
Louise LantierVanderbilt University


Genomic Information
GeneAllele 1Allele 2Protocol
Prkaa1knockin (lox)knockin (lox)Not Specified
Prkaa2knockin (lox)knockin (lox)Not Specified


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