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Strain
C57BL/6-Tg(aP2-Zfp516)1Mss

Summary Data Summary
Official Name C57BL/6-Tg(aP2-Zfp516)1Mss
Common Name C57BL/6-Tg(aP2-Zfp516)1Mss
Description Generated transgenic mouse lines over express Zfp516 driven
by the -5.4kb aP2 promoter. Although endogenous Zfp516
expression is significantly higher in BAT than WAT, the fold
increase of Zfp516 in iWAT and pWAT of transgenic mice was
greater than in BAT (50-fold versus 10-fold). Zfp516
expression in other tissues was unaffected.
Development Status Phenotyping ongoing
Creation Method transgenic
TypeCount
Investigators 1
Genomics - Transgenes 1
Experiments 1


Investigators
NameInstitution
Gerald I. ShulmanYale University


Genomic Information
EnhancerPromoterGeneCopies
Not SpecifiedFabp4Zfp516Not Specified


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