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Strain
CD-Tg(RP11-466I19/Tcf7l2)1Nobr

Summary Data Summary
Official Name CD-Tg(RP11-466I19/Tcf7l2)1Nobr
Common Name C57BL/6-Tg(RP11-466I19/Tcf7l2)1Nobr
Description The corresponding mouse sequence was inserted at the
translation initiation codon in human TCF7L2 of BAC
RP11-466I19. Line 1 contains three copies of the transgene.
BAC overexpression of Tcf7l2 in mice followed by high fat
diet causes a glucose intolerant phenotype modeling T2D.
Development Status Phenotyping ongoing
Creation Method transgenic
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Transgenes 1
Experiments 5


Investigators
NameInstitution
Kathleen BaileyUniversity of Chicago


Genomic Information
EnhancerPromoterGeneCopies
Not SpecifiedNot SpecifiedTcf7l23


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