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Strain
B6J.Cg-Taf7ltm1.1Jw

Summary Data Summary
Official Name B6J.Cg-Taf7ltm1.1Jw
Common Name B6J.Cg-Taf7ltm1.1Jw
Description In the Taf7l targeting construct loxP sites were introduced
into the first and sixth introns. ES cells harboring the
Taf7l flox allele were injected into BALB/c blastocysts that
were subsequently transferred to uteri of pseudopregnant
Swiss Webster females. The resulting male chimeras were bred
with BALB/c females to obtain germ line transmission of
injected ES cells. Agouti females were genotyped by PCR.
Taf7l flox mice were crossed with Tg(ACTB-cre)2Mrt
transgenic mice to obtain the Taf7l- (mutant) allele. The
Tg(ACTB-cre)2Mrt transgene was subsequently removed from
Taf7l mutant mice by breeding. We backcrossed Taf7l+/- mice
to C57BL/6J (B6) and 129 strains for more than five
generations.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 2


Investigators
NameInstitution
Gerald I. ShulmanYale University


Genomic Information
GeneAllele 1Allele 2Protocol
Taf7lknockoutwildNot Specified


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