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Strain
C57BL/6-Acsl4tm1Asg Tg(Adipoq-Cre)1Evdr

Summary Data Summary
Official Name C57BL/6-Acsl4tm1Asg Tg(Adipoq-Cre)1Evdr
Common Name C57BL/6-Acsl4tm1Asg Tg(Adipoq-Cre)
Description loxP sites were inserted in the Acyl-CoA synthetase
long-chain family member (Acsl4) gene.

The mouse was subsequently bred to a mouse with the
Adipoq-Cre transgene to delete the Acsl4 gene from adipose
tissue.
Development Status Phenotyping ongoing
Creation Method knockout
Background C57BL/6
Breeding Type intercross
Phenotype Description This mouse exhibits reduced body fat accumulation, reduced
adipose tissue inflammation, reduced hepatic steatosis, and
improved insulin tolerance test and reduced serum insulin.
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Experiments 1


Investigators
NameInstitution
Andrew GreenbergTufts University


Genomic Information
GeneAllele 1Allele 2Protocol
Acsl4knockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedAdipoqCRENot Specified


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