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Strain
FVB-Tg(Myh6-SOD2,Tyr)3Pne

Summary Data Summary
Official Name FVB-Tg(Myh6-SOD2,Tyr)3Pne
Common Name FVB-Tg(Myh6-SOD2,Tyr)3Pne
Description A transgenic construct containing the human, superoxide
dismutase 2, mitochondrial gene under the control of the
mouse myosin, heavy polypeptide 6, cardiac muscle, alpha,
promoter and a polyadenylation sequence (550-bp fragment of
the rat insulin II gene) was co-injected with a tyrosinase
minigene where tyrosinase is under the control of the
tyrosinase promoter, commonly referred to as TyBs into
fertilized FVB mouse eggs. Founder line 3 was subsequently
established.
Development Status Phenotyping ongoing
Creation Method transgenic
Breeding Type backcross
TypeCount
Investigators 1
Genomics - Transgenes 1
Experiments 1


Investigators
NameInstitution
Machelle PardueEmory University


Genomic Information
EnhancerPromoterGeneCopies
Not SpecifiedMyh6SOD2Not Specified


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