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Strain
B6.BKS-Dock7m +/+ Leprdb Dusp1tm1Brv

Summary Data Summary
Official Name B6.BKS-Dock7m +/+ Leprdb Dusp1tm1Brv
Common Name db/db;mkp-1 ko
Description Female C57BL6/J mkp-1+/ mice as described previously (16)
were crossed to BKS.Cg-m+/+ Leprdb/J breeder pairs (Jackson
Laboratories) until both gray and obese pups were obtained
in the same litter, indicating the presence of both db and m
alleles. db/m;mkp-1+/ mice were intercrossed to obtain
db/db;mkp-1+/+ mice and db/db;mkp-1/ mice.
Development Status Phenotyping ongoing
Creation Method knockout
Breeding Type intercross
TypeCount
Investigators 1
Genomics - Modifications 3
Experiments 1


Investigators
NameInstitution
Rachel RothYale University


Genomic Information
GeneAllele 1Allele 2Protocol
Dusp1knockoutknockoutNot Specified
Dock7nucleotide insertionnucleotide insertionNot Specified
Leprpoint mutation - transversionpoint mutation - transversionNot Specified


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