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Strain
B6.129S-Itga5tm1Hyn

Summary Data Summary
Official Name B6.129S-Itga5tm1Hyn
Common Name B6.129S-Itga5tm1Hyn
Description A neomycin resistance cassette replaced 330 bp of the gene,
deleting most of the first exon.
Development Status Phenotyping ongoing
Creation Method knockout
Phenotype Description Mice homozygous for the Itga5tm1Hyn targeted mutation die
during embryonic development. Homozygous mutant embryos
exhibit defects in the vasculature of the yolk sac and the
embyro as well as severe defects in posterior and
extraembryonic mesoderm. Implantation and initiation of
gastrulation and neurulation is normal. There is normal
development of notochord, somite and considerable
development of brain, optic and otic anlagen and branchial
arches.
TypeCount
Investigators 1
Genomics - Modifications 1
Experiments 1


Investigators
NameInstitution
Neha BhatYale University


Genomic Information
GeneAllele 1Allele 2Protocol
Itga5knockoutknockoutNot Specified


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