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Strain
C57BL/6-Nos1tm3Plh Tg(ACTA1-cre)79Jme

Summary Data Summary
Official Name C57BL/6-Nos1tm3Plh Tg(ACTA1-cre)79Jme
Common Name C57BL/6-Nos1tm3Plh Tg(ACTA1-cre)79Jme
Description Nos1 flox: A conditional allele of Nos1 was generated in
which exon 6 is flanked by lox sites.

ACTA1 transgene: This transgene expresses Cre recombinase
under the control of a human alpha-skeletal actin promoter,
active in striated muscle, heart, and skeletal muscle.
Development Status Phenotyping ongoing
Creation Method transgenic
Phenotype Description Model useful for understanding the consequences of loss of
skeletal muscle NOS1 function as seen in type 2 diabetes and
Duchenne muscular dystrophy
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1
Experiments 1


Investigators
NameInstitution
Justin PercivalUniversity of Washington


Genomic Information
GeneAllele 1Allele 2Protocol
Nos1knockin (lox)knockin (lox)Not Specified
EnhancerPromoterGeneCopies
Not SpecifiedACTA1CRENot Specified


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