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Strain
STOCK Smarca4tm1.1Grc Tg(Adipoq-cre)1Evdr/J

Summary Data Summary
Official Name STOCK Smarca4tm1.1Grc Tg(Adipoq-cre)1Evdr/J
Common Name STOCK Smarca4tm1.1GrcTg(Adipoq-cre)1Evdr/J
Description The Dendra2 sequence, along with a floxed neomycin cassette,
was inserted into the C-terminus of the Smarca4 gene via
homologous recombination in 129-derived embryonic stem
cells. The targeting construct was derived from BAC
bMQ-242m22. The neomycin cassette was later excised. This
strain was maintained on a mixed C57BL/6-129 genetic
background by the donating laboratory.
Mice harboring the Adipoq-Cre BAC transgene express Cre
recombinase under control of the mouse adiponectin (Adipoq)
promoter/enhancer regions within the BAC transgene.
Adipoq-Cre BAC transgenic mice are a Cre-lox tool for
deletion of floxed sequences in white adipose tissue and
brown adipose tissue, but not in activated or resident
macrophages.
Development Status Phenotyping ongoing
Creation Method knockout
TypeCount
Investigators 1
Genomics - Modifications 1
Genomics - Transgenes 1


Investigators
NameInstitution
Ai-jun SunFudan University


Genomic Information
GeneAllele 1Allele 2Protocol
Smarca4knockoutknockoutNot Specified
EnhancerPromoterGeneCopies
Not SpecifiedAdipoqCRENot Specified

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