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Center Core
M&MH Core

Center University of California Davis
Description The Metabolism & Metabolic Health (M&MH) Core provides phenotyping services for
the assessment of metabolic physiology in mouse models relevant to obesity,
diabetes, and cardiometabolic health. The Core offers users the expertise,
technical resources, and instrumentation necessary to characterize perturbations
in endocrine systems, bioenergetics, and metabolism. The Core performs assays
and data interpretation for in vivo phenotyping including metabolic rate and
whole-body substrate utilization, glucose tolerance and insulin sensitivity,
systemic metabolomics, hepatic triglyceride production, microbiota metabolism
(xenometabolomics) and microbiome characterization, in vivo imaging and body
composition, food intake behaviors including food preference, quantitative
energy balance measures, and endocrinology. The Core will also give prioritized
and subsidized support, training, and consultation to VIBRANT-eligible
researchers. The Core is led by Sean H. Adams, PhD, and Co-led by Peter J.
Havel, DVM, PhD, with coordination and expertise from Michael Goodson, PhD and
Douglas Rowland, PhD. The Core also includes scientific consultants in
bioenergetics (Jon Ramsey), metabolomics and xenometabolomics (Oliver Fiehn,
Trina Knotts, Brian Piccolo), and continuous glucose monitoring (Mark Huising).
James Graham and Todd Tolentino are the Core’s expert technical staff.
Center Core RRID SCR_015359 (Link)
Is Subcore? No
Is Inactive? No

Peter HavelUniversity of California - Davispjhavel@ucdavis.eduCo-Director
Sean AdamsUniversity of California Davisshadams@ucdavis.eduDirector
Michael GoodsonUniversity of California - Davismlgoodson@ucdavis.eduPersonnel
Doug RowlandUniversity of California Davisdjrowland@ucdavis.eduPersonnel


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