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Center Core
P&B Core

Center University of California Davis
Description The goal of the Physiology and Behavior (P&B) Core is to advance the
understanding of behavioral manifestations and pathophysiological mechanisms and
systemic consequences of diabetes, obesity, and related metabolic disorders. The
Core provides investigators with a range of phenotyping tests and services for
the in vivo characterization of ocular, kidney, cardiovascular, and
gastrointestinal functions in mice. The Core also offers tests that allow
investigators to study manifestations of peripheral neuropathy (nociception,
gait & ambulation, and wound healing), a common complication of diabetes.
Another important component of this Core is to understand how obesity and
metabolic disorders influence executive and neurophysiological functions. For
this, the Core offers a battery of behavioral (learning, memory, sociability,
and anxiety) and neuromotor (gait, ambulation, force) tests to comprehensively
interrogate the multifaceted behavioral domains. This Core also has expertise in
evaluating exercise and sleep activities. The Core can assist investigators in
all steps of the research process, from designing experiments to analyzing and
interpreting data. The Core is led by Louise Lanoue PhD and Jill L Silverman
PhD. The Core also includes scientific consultants in ophthalmology (Morshiri
Ala MD, PhD), cardiology (Nipivan Chiamvimovat MD), renal function (Maryam
Afkarian MD, PhD) and wound healing (Scott Simon PhD). Todd Tolentino is the
Core’s expert technical staff.
Center Core RRID SCR_015364 (Link)
Is Subcore? No
Is Inactive? No


 Members
NameInstitutionEmailTitle
Louise LanoueUniversity of California Davisllanoue@ucdavis.edu
Jill SilvermannUniversity of California Davisjsilverman@ucdavis.eduDirector

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