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Experiment

BBB permeability in LDLr and COntrol mice on Western diet
Summary Data Summary
Investigator Lee, Linda
Description Both C57BL6/J and LdlR knock out mic we feed either a control or western diet
(Harlan TD..08485 and 88137) form age 8 weeks to 20. At which time animals will
have their baseline BBB permeability determined by MRI.

Applicable research area(s): Diabetes, Metabolism, Cardiovascular, Neurobiology
Status Completed
Public Release 10/23/2017
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flag
Data Analysis
TypeCount
Animals32
Experimental Conditions2
Catalog Items2
Curation Info (# flags)0
Phenotype Assays1
Phenotype Measurements32
Histology Images0
Publications0


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6
0
16
0
C57BL/6J-Ldlr-/-
0
16
0

Animals/Strains
Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Mouse Diet

 Teklad - 08485
Harlan Teklad TD.08485 Low Fat Control Diet Purified Diet, Modification of TD.88137, Low Fat & No Added Cholesterol, Reduced Sucrose.
 Teklad - 88137
Harlan Teklad TD.88137 (Western Diet)
Experimental Factor (Units)
Experimental Group
Mouse Diet
Experimental Factor Values


Phenotype Assays Add / Edit


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