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Experiment

HYPERINSULINEMIC CLAMP - HYPERINSULINEMIC CLAMP - V3005 PXN1218, V3005A PXN1218
Summary Data Summary
Investigator Wasserman, David
Description HYPERINSULINEMIC CLAMP

These mice have GLUT4 and/or HK II overexpressed. HK II is on the CrK promotor

Applicable research area(s): Diabetes, Metabolism
Status Completed
Public Release 9/18/2010
Animal Age Measured In: week(s) post-natal (w)
Flags has-data-flagSame StrainAnimal CountExperiment Description
Data Analysis
TypeCount
Animals105
Experimental Conditions4
Catalog Items1
Curation Info (# flags)3
Phenotype Assays19
Phenotype Measurements1591
Histology Images0
Publications0
Phenotypes2


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6J
2
4
0
C57BL/6-Tg(Slc2a4)
17
20
1
C57BL/6J-Tg(Slc2a4) Tg(Hk2)
16
19
0
C57BL/6J-Tg(OE-Hk2)
17
9
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Glucose Infusion Rate (mg/kg/min)

 Glucose Infusion Rat
Rate of glucose infusion for clamp experiments

Experimental Factor: Insulin Dose (mU/kg)

 Insulin Dose

Experimental Factor: Mouse Diet

 BioServ F3282
Rodent Hig Fat Diet. Protein 20.%, Fat 35.5%, Fiber 0.0%, Ash 3.2%, Moisture <5.0%, Carbohydrate 36.3%. Ingredients: Lard, Casein, Dextrose, Sucrose, DL-Methionine, Choline Chloride, Vitamin Mix and Mineral Mix
 LabDiet 5001
crude protein (23.0%), crude fat (4.5%), crude fiber (6.0%), Ash (< 8.0%), minerals (2.5%)


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