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Experiment

Hyperinsulinemic clamp order #18464 ,December 2015
Summary Data Summary
Investigator Gross, Richard
Description Our KO mouse line is an enabling model to dissect the tissue-specific mechanisms
linking inflammation, dysfunctional lipid metabolism and maladaptive signaling
that promote insulin resistance, obesity and hepatic steatosis during HF
feeding.

Applicable research area(s): Diabetes, Obesity, Cardiovascular
Status Completed
Public Release 4/20/2018
Animal Age Measured In: week(s) post-natal (w)
Data Analysis
TypeCount
Animals22
Experimental Conditions4
Catalog Items1
Curation Info (# flags)0
Phenotype Assays16
Phenotype Measurements4989
Histology Images0
Publications0
Phenotypes5


Animals
Strain NameCommon NameFemalesMalesUnknown
C57BL/6-Pnpla8tm1Rigr
0
11
0
C57BL/6-Pnpla8tm2Rigr Tg(Alb-Cre)
0
11
0

Experimental Factors
 Categorical Values
Name / AbbreviationDescription

Experimental Factor: Experimental Group

 Control
This animal belongs to the control group for the experiment.
 Experiment
This animal belongs to experimental group that is homozygous for gene manipulations.

Experimental Factor: Glucose Infusion Rate (mg/kg/min)

 Glucose Infusion Rat
Rate of glucose infusion for clamp experiments

Experimental Factor: Mouse Diet

 Teklad - 7012
Crude Protein (Min) 19.0%, Crude Fat (Min) 5.0%, Crude Fiber (Max) 5.0%, Protein %19.92, Fat %5.67, Fiber %4.37, Ash %6.48, Ingredients - Ground corn, dehulled soybean meal, ground oats, wheat middlings, dehydrated alfalfa meal, soybean oil, corn...

Experimental Factor: Time Sample Taken (min)

 Time Sample Taken
Time in minutes since a sample was taken


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